Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Domenica Spadaro"'
Autor:
Martina Rossi, Gabriele Bucci, Dario Rizzotto, Domenico Bordo, Matteo J. Marzi, Margherita Puppo, Arielle Flinois, Domenica Spadaro, Sandra Citi, Laura Emionite, Michele Cilli, Francesco Nicassio, Alberto Inga, Paola Briata, Roberto Gherzi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Several lncRNAs are regulated by TGF-β. Here the authors report that an intergenic lncRNA —EPR— is a component of the TGF-β signaling pathway and controls epithelial cell proliferation by altering transcription and mRNA decay of Cdkn1a. EPR ove
Externí odkaz:
https://doaj.org/article/d6f7e15deb314cbf950c9b2234270de8
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55873 (2013)
The cytoplamic junctional proteins cingulin and paracingulin have been implicated in the regulation of gene expression in different cultured cell models. In renal epithelial MDCK cells, depletion of either protein results in a Rho-dependent increase
Externí odkaz:
https://doaj.org/article/8e4ab20d256442878aed21d1a8b161af
Autor:
Ekaterina, Vasileva, Domenica, Spadaro, Florian, Rouaud, Jonathan M, King, Arielle, Flinois, Jimit, Shah, Sophie, Sluysmans, Isabelle, Méan, Lionel, Jond, Jerrold R, Turner, Sandra, Citi
Publikováno v:
The Journal of biological chemistry. 298(4)
Zonula occludens-1 (ZO-1), the major scaffolding protein of tight junctions (TJs), recruits the cytoskeleton-associated proteins cingulin (CGN) and paracingulin (CGNL1) to TJs by binding to their N-terminal ZO-1 interaction motif. The conformation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7e0c0e2405cd1fc9c17f9a305cdc256
https://pubmed.ncbi.nlm.nih.gov/35259394
https://pubmed.ncbi.nlm.nih.gov/35259394
Autor:
Sophie Sluysmans, Wenmao Huang, Vera Dugina, Jimit Shah, Christine Chaponnier, Adai Colom, Domenica Spadaro, Jie Yan, Arielle Flinois, Florian Rouaud, Isabelle Méan, Ekaterina Vasileva, Sandra Citi, Lionel Jond, Aurélien Roux
SUMMARYHow junctional proteins regulate the mechanics of the plasma membrane and how actin and myosin isoforms are selectively localized at epithelial cell-cell junctions is poorly understood. Here we show by atomic force indentation microscopy, immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda37d954daf1304130ea9dae6cc95f2
https://doi.org/10.1101/2020.05.14.095364
https://doi.org/10.1101/2020.05.14.095364
Autor:
Sophie Sluysmans, Sandra Citi, Florian Rouaud, Jimit Shah, Ekaterina Vasileva, Domenica Spadaro
Publikováno v:
Biology of the Cell. 109:139-161
Tissues of multicellular organisms are characterised by several types of specialised cell-cell junctions. In vertebrate epithelia and endothelia, tight and adherens junctions (AJ) play critical roles in barrier and adhesion functions, and are connect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2d69884bf3bdf26ea73e4bdcc39b6c
https://doi.org/10.1111/boc.201600075
https://doi.org/10.1111/boc.201600075
Autor:
Francesco Nicassio, Margherita Puppo, Gabriele Bucci, Martina Rossi, Dario Rizzotto, Alberto Inga, Sandra Citi, Domenico Bordo, Paola Briata, Arielle Flinois, Laura Emionite, Domenica Spadaro, Michele Cilli, Matteo Jacopo Marzi, Roberto Gherzi
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Long noncoding RNAs (lncRNAs) are emerging as regulators of fundamental biological processes. Here we report on the characterization of an intergenic lncRNA expressed in epithelial tissues which we termed EPR (Epithelial cell Program Regulator). EPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb17df9a2c8a0cf1f49192c2fe1aaf2d
http://europepmc.org/articles/PMC6488594
http://europepmc.org/articles/PMC6488594
Autor:
Jie Yan, Domenica Spadaro, Thierry Laroche, Isabelle Méan, Sandra Citi, Lionel Jond, Shimin Le
Publikováno v:
Current biology : CB. 27(24)
Summary Tensile forces regulate epithelial homeostasis, but the molecular mechanisms behind this regulation are poorly understood. Using structured illumination microscopy and proximity ligation assays, we show that the tight junction protein ZO-1 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf28437ce0cc89ba22fd363f4720db8
https://pubmed.ncbi.nlm.nih.gov/29199076
https://pubmed.ncbi.nlm.nih.gov/29199076
Publikováno v:
Molecular Biology of the Cell
The Rac1 inhibitor MgcRacGAP regulates Rac1 activation and TJ barrier development during junction assembly in epithelial cells. CGN and CGNL1 recruit MgcRacGAP to the TJ and interact with MgcRacGAP.
The regulation of Rho-family GTPases is crucia
The regulation of Rho-family GTPases is crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42284703098300336be71e0ca88528b3
https://doi.org/10.1091/mbc.e13-11-0680
https://doi.org/10.1091/mbc.e13-11-0680
Publikováno v:
Tissue Barriers
The barrier function of epithelia and endothelia depends on tight junctions, which are formed by the polymerization of claudins on a scaffold of ZO proteins. Two differentially spliced isoforms of ZO-1 have been described, depending on the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc9ba16442d4f68f3d5fe6c0c31c28d
https://doi.org/10.1080/21688370.2019.1653748
https://doi.org/10.1080/21688370.2019.1653748
Autor:
Sophie, Sluysmans, Ekaterina, Vasileva, Domenica, Spadaro, Jimit, Shah, Florian, Rouaud, Sandra, Citi
Publikováno v:
Biology of the cell. 109(4)
Tissues of multicellular organisms are characterised by several types of specialised cell-cell junctions. In vertebrate epithelia and endothelia, tight and adherens junctions (AJ) play critical roles in barrier and adhesion functions, and are connect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbe3917e2970edc870621d9cb087b9a6
https://pubmed.ncbi.nlm.nih.gov/28220498
https://pubmed.ncbi.nlm.nih.gov/28220498