Transgenic Mice Expressing Mutant Notch3 Develop Vascular Alterations Characteristic of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

Autor: Ruchoux, Marie Magdeleine, Domenga, Valérie, Brulin, Peggy, Maciazek, Jacqueline, Limol, Sylvie, Tournier-Lasserve, Elisabeth, Joutel, Anne

Publikováno v: In The American Journal of Pathology 2003 162(1):329-342

Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries

Autor: Belin De Chantemèle, Eric, Retailleau, Kevin, Pinaud, Frédéric, Vessières, Emilie, Bocquet, Arnaud, Guihot, Anne-Laure, Lemaire, Barbara, Domenga, Valérie, Baufreton, Christophe, Loufrani, Laurent, Joutel, Anne, Henrion, Daniel

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2008, 28 (12), pp.2216-24. ⟨10.1161/ATVBAHA.108.171751⟩

International audience; OBJECTIVE: Notch3, a member of the evolutionary conserved Notch receptor family, is primarily expressed in vascular smooth muscle cells. Genetic studies in human and mice revealed a critical role for Notch3 in the structural i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::cae4a8884edf8b6456cc9be5da3b831b
https://www.hal.inserm.fr/inserm-00326627

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Impaired cerebral vasoreactivity in a transgenic mouse model of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy arteriopathy.

Autor: Lacombe, Pierre, Oligo, Charleen, Domenga, Valérie, Tournier-Lasserve, Elisabeth, Joutel, Anne

Publikováno v: Stroke (00392499); 2005 May, Vol. 36 Issue 5, p1053-1058, 6p