Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Domantas Motiejunas"'
Autor:
Bernd Segnitz, Domantas Motiejunas, Rebecca C. Wade, Klemens Wild, Astrid Hendricks, Irmgard Sinning, Judith F. Kribelbauer, Gert Bange
Publikováno v:
Journal of molecular biology. 428(14)
The signal recognition particle (SRP) is a ribonucleoprotein complex with a key role in targeting and insertion of membrane proteins. The two SRP GTPases, SRP54 (Ffh in bacteria) and FtsY (SRα in eukaryotes), form the core of the targeting complex (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b023850614393ddd533b62912eef3
https://pubmed.ncbi.nlm.nih.gov/27241309
https://pubmed.ncbi.nlm.nih.gov/27241309
Autor:
Paul A.M. Michels, Domantas Motiejunas, Véronique Hannaert, M. Paola Costi, Samuele Calò, Erika Nerini, Shreedhara Gupta, Alberto Venturelli, Stefan Henrich, Sandra Lazzari, Rosaria Luciani, Stefania Ferrari, Rebecca C. Wade, Federica Morandi
Publikováno v:
ResearcherID
Folate analogue inhibitors of Leishmania major pteridine reductase (PTR1) are potential antiparasitic drug candidates for combined therapy with dihydrofolate reductase (DHFR) inhibitors. To identify new molecules with specificity for PTR1, we carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30939b1c3bce24ea0e6f8146e0af3aa4
https://doi.org/10.1021/jm1010572
https://doi.org/10.1021/jm1010572
Autor:
Rebecca C. Wade, Peter J. Winn, Anna Feldman-Salit, Tim Johann, Ting Wang, Domantas Motiejunas, Razif R. Gabdoulline
Publikováno v:
Proteins. 71(4)
We present a computational procedure for modeling protein-protein association and predicting the structures of protein-protein complexes. The initial sampling stage is based on an efficient Brownian dynamics algorithm that mimics the physical process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29378daa2db90094940fe7da4ae34fe
https://pubmed.ncbi.nlm.nih.gov/18186463
https://pubmed.ncbi.nlm.nih.gov/18186463
Autor:
Domantas Motiejunas, Rebecca C. Wade
This chapter describes the physical factors contributing to ligand–receptor complexation and discusses the computational models of the energetics of ligand–receptor binding. Examples of the role of different interactions, as well as molecular fle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba695b6b8fe3e6cf0e082e5ca987b648
https://doi.org/10.1016/b0-08-045044-x/00250-9
https://doi.org/10.1016/b0-08-045044-x/00250-9
Publikováno v:
Biochimica et biophysica acta. 1770(3)
Recently we have developed a new approach to study protein-protein interactions using Fourier transform infrared spectroscopy in combination with titration experiments and principal component analysis (FTIR-TPCA). In the present paper we review the F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a416f2deb907daf09c27e28f5e4a051e
https://pubmed.ncbi.nlm.nih.gov/17014964
https://pubmed.ncbi.nlm.nih.gov/17014964
Autor:
Peter J. Winn, Karin Schleinkofer, Sudarko, Domantas Motiejunas, Amit Banerjee, Rebecca C. Wade, Christiane Jung, Andrei Kariakin
Publikováno v:
Biochimica et biophysica acta. 1754(1-2)
Biomolecular recognition is complex. The balance between the different molecular properties that contribute to molecular recognition, such as shape, electrostatics, dynamics and entropy, varies from case to case. This, along with the extent of experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2019d1f4c52b87e852fa43fa6694976a
https://pubmed.ncbi.nlm.nih.gov/16226496
https://pubmed.ncbi.nlm.nih.gov/16226496
Autor:
Stefania Ferrari, Federica Morandi, Domantas Motiejunas, Erika Nerini, Stefan Henrich, Rosaria Luciani, Alberto Venturelli, Sandra Lazzari, Samuele CaloÌ, Shreedhara Gupta, Veronique Hannaert, Paul A. M. Michels, Rebecca C. Wade, M. Paola Costi
Publikováno v:
Journal of Medicinal Chemistry; Jan2011, Vol. 54 Issue 1, p211-221, 11p