Zobrazeno 1 - 10
of 839
pro vyhledávání: '"Domain family"'
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disease that causes cognitive dysfunction in older adults. One of the AD pathological factors, β-Amyloid (Aβ), triggers inflammatory responses and phagocytosis of microglia. C-ty
Externí odkaz:
https://doaj.org/article/8fec39495d024e938bed4c6fc44d369b
Autor:
Safia Iqbal, Md. Rezaul Karim, Shahnawaz Mohammad, Ramya Mathiyalagan, Md. Niaj Morshed, Deok-Chun Yang, Hyocheol Bae, Esrat Jahan Rupa, Dong Uk Yang
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5488-5510 (2024)
The PHLDA (pleckstrin homology-like domain family) gene family is popularly known as a potential biomarker for cancer identification, and members of the PHLDA family have become considered potentially viable targets for cancer treatments. The PHLDA g
Externí odkaz:
https://doaj.org/article/1b079143695f4a43b9ccd97ff439b63a
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200823- (2024)
In the field of innovative cancer treatment strategies, oncolytic vaccinia virus (VV)es have gained traction as promising vectors. In the current study, we inserted the human C-type lectin domain family 2 member A (CLEC2A) gene into VV, creating a re
Externí odkaz:
https://doaj.org/article/4046597af92747dbafb8310fc3d7cae0
Publikováno v:
Guoji laonian yixue zazhi, Vol 45, Iss 1, Pp 46-52 (2024)
Objective To investigate the effect of YTH domain family protein 1(YTHDF1) on apoptosis and oxidative damage in H9c2 cells under hypoxic reoxygenation(H/R) conditions. Methods The H/R model was constructed with H9c2 cells.Cells were transfected with
Externí odkaz:
https://doaj.org/article/0fa95c3749c6492caefd72395639c9aa
Autor:
Liyun Song, Daoshun Zhang, Tianbo Liu, Changqing Jiang, Bin Li, Changquan Li, Lili Shen, Ying Li, Fenglong Wang, Yubing Jiao, Jinguang Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Viral diseases continue to pose a major threat to the world’s commercial crops. The in-depth exploration and efficient utilization of resistance proteins have become crucial strategies for their control. However, current deliver
Externí odkaz:
https://doaj.org/article/af46034ace534cfa97f2b450cc5035ab
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Long non-coding RNA (lncRNA) HOXA cluster antisense RNA 3 (HOXA-AS3) regulates the progression of several types of human malignancy. However, the role and potential mechanism of HOXA-AS3 in osteosarcoma (OS) remain unknown. In this study, up
Externí odkaz:
https://doaj.org/article/8b8f0fd568464fd1be2c92a6a204992b
Publikováno v:
Genes and Diseases, Vol 10, Iss 5, Pp 2179-2193 (2023)
Uveitis, a vision-threatening inflammatory disease worldwide, is closely related to resident microglia. Retinal microglia are the main immune effector cells with strong plasticity, but their role in uveitis remains unclear. N6-methyladenosine (m6A) m
Externí odkaz:
https://doaj.org/article/f197ebef6039419e8dbf63330df0bb2c
Autor:
Kalyan Mahapatra
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 1, Pp 100333- (2024)
SOG1 is a crucial plant-specific NAC domain family transcription factor and functions as the central regulator of DNA damage response, acting downstream of ATM and ATR kinases. In this study, various in-silico approaches have been employed for the ch
Externí odkaz:
https://doaj.org/article/a460afbcf1b34243b951028ff4332560
Publikováno v:
Biomolecules & Biomedicine, Vol 24, Iss 1 (2024)
Gastric cancer (GC) is a prevalent malignant cancer characterized by a poor survival rate. The C-type lectin domain family 11 member A (CLEC11A) is part of the C-type lectin superfamily, and its dysregulation has been implicated in the progression of
Externí odkaz:
https://doaj.org/article/c26fe1863c2e4a1c8d0c89aa80ae46ce
Autor:
Chunya Zhou, Shiya Cai, Yuhong Xie, Zhen Zeng, Jun Zhang, Guannan Su, Qiuying Wu, Xingsheng Ye, Qingfeng Cao, Peizeng Yang, Jianmin Hu
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-8 (2023)
Abstract Background Protein kinase C delta (PRKCD) and caspase recruitment domain family member 9 (CARD9) are genes involved in B and T cell activation, and cytokine production, which are vital mechanisms underlying autoimmune disease development. Th
Externí odkaz:
https://doaj.org/article/0f28354e44be40cb97843619ac227687