Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dolph D. Ellefson"'
Autor:
H. Maulhardt, Gere S. diZerega, Norma Roda, Sonia Maldonado, Theresa Espinoza, Kathleen E. Rodgers, Dolph D. Ellefson
Publikováno v:
The Journal of Peptide Research. 66:41-47
The renin angiotensin system (RAS) has been shown to be present in dermal tissue and exogenous peptides from the RAS accelerates healing and reduces scarring. An analogue of Angiotensin(1–7) [A(1–7)], Norleucine3-A(1–7) [Nle3-A(1–7)], is the
Publikováno v:
Wound Repair and Regeneration. 13:A28-A48
Neuropathic ulcers represent a significant cause of morbitity for diabetics in the United States. Diabetic wounds are notoriously difficult to resolve. Treatment options are limited due in part to the lack of knowledge about the molecular events that
Autor:
Dolph D. Ellefson, Ya-Hsuan Hsu, Ruty Mehrian-Shai, Gere S. diZerega, Theresa Espinoza, Kathleen E. Rodgers
Publikováno v:
Wound Repair and Regeneration. 14:298-305
Reports have shown differences in gene expression in the skin of diabetic and normal mice both at baseline and after injury. Cluster analysis identified distinct expression patterns within intermediate filaments and extracellular proteins. This repor
Effect of NorLeu3-A(1-7) on scar formation over time after full-thickness incision injury in the rat
Autor:
Sonia Maldonado, Dolph D. Ellefson, Norma Roda, Kathleen E. Rodgers, Theresa Espinoza, Gere S. diZerega
Publikováno v:
Wound Repair and Regeneration. 13:309-317
Previous studies have shown that the angiotensin peptide NorLeu3-A(1-7) accelerates dermal healing and reduces scar formation. In this report, the effect of this peptide on scar formation is more fully delineated. The effect of surgical day, time aft
Publikováno v:
Biochemistry. 37:12269-12279
The interaction of CheA with ATP has important consequences in the chemotaxis signal transduction pathway of Escherichia coli. This interaction results in autophosphorylation of CheA, a histidine protein kinase. Autophosphorylation of CheA sets in mo
Publikováno v:
Journal of Surgical Research. 56:314-325
Previous studies showed that tolmetin administered as a single instillate intraperitoneally at the end of surgery can reduce adhesion formation. In this report, studies on the mechanism by which this occurs were conducted. The effects of tolmetin adm
Autor:
Kathleen E. Rodgers, Dolph D. Ellefson
Publikováno v:
Agents and Actions. 35:57-63
Malathion is a widely used organophosphate pesticide that modulates immune function at noncholinergic doses. Previous studies showed that this alteration in immune function was the result of enhanced macrophage function. In the present study, the eff
Publikováno v:
Journal of Investigative Surgery. 4:141-151
Macrophages play a crucial role in wound healing after surgical injury, both as scavenger cells responsible for wound debridement and as cells that secrete soluble factors such as interleukin-1 (IL-1) and tumor necrosis factor (TNF). IL-1 and TNF alt
Autor:
Kathleen E. Rodgers, Dolph D. Ellefson, Wefki Girgis, Gere S. diZerega, Joseph D. Campeau, Hiromasa Abe
Publikováno v:
Journal of Surgical Research. 49:322-327
Intraperitoneal administration of sodium tolmetin-hyaluronic acid reduced the formation of adhesions at early postsurgical time points. In addition, at 6, 48, 72, and 96 hr following surgery, there was a significant reduction in the number of red blo
Autor:
Kathleen E. Rodgers, Dolph D. Ellefson
Publikováno v:
Fundamental and Applied Toxicology. 14:309-317
Previous studies showed that acute administration of noncholinergic doses of malathion in vivo elevated the humoral immune and mitogenic responses but did not alter the generation of the cytotoxic T lymphocyte (CTL) response to alloantigen of splenoc