Single-nucleotide polymorphism array-based karyotyping of acute promyelocytic leukemia.

Autor: Inés Gómez-Seguí, Dolors Sánchez-Izquierdo, Eva Barragán, Esperanza Such, Irene Luna, María López-Pavía, Mariam Ibáñez, Eva Villamón, Carmen Alonso, Iván Martín, Marta Llop, Sandra Dolz, Oscar Fuster, Pau Montesinos, Carolina Cañigral, Blanca Boluda, Claudia Salazar, Jose Cervera, Miguel A Sanz

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e100245 (2014)

Acute promyelocytic leukemia (APL) is characterized by the t(15;17)(q22;q21), but additional chromosomal abnormalities (ACA) and other rearrangements can contribute in the development of the whole leukemic phenotype. We hypothesized that some ACA not

Externí odkaz: https://doaj.org/article/38079d609c6f4593990562fca5b858ba

miR‐200c and phospho‐AKT as prognostic factors and mediators of osteosarcoma progression and lung metastasis

Autor: Pablo Berlanga, Lisandra Muñoz, Marta Piqueras, J. Antoni Sirerol, María Dolors Sánchez-Izquierdo, David Hervás, Miguel Hernández, Margarita Llavador, Isidro Machado, Antonio Llombart-Bosch, Adela Cañete, Victoria Castel, Jaime Font de Mora

Publikováno v: Molecular Oncology, Vol 10, Iss 7, Pp 1043-1053 (2016)

Lung metastasis is the major cause of death in osteosarcoma patients. However, molecular mechanisms underlying this metastasis remain poorly understood. To identify key molecules related with pulmonary metastasis of pediatric osteosarcomas, we analyz

Externí odkaz: https://doaj.org/article/35c63685a92047168d785cf5d9ac552b

Circulating MicroRNAs as Novel Biomarkers of Stenosis Progression in Asymptomatic Carotid Stenosis

Autor: Jose Ignacio Tembl, Vera Parkhutik, Sandra Dolz, Dolors Sánchez, Aida Lago, Gerardo Fortea, David Gorriz

Publikováno v: Stroke
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Background and Purpose— Progression of asymptomatic carotid artery stenosis (ACAS) in patients with >50% luminal narrowing is considered a potential risk factor for ischemic stroke; however, subclinical molecular biomarkers of ACAS progression are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302b0a3ebbf86102d075ed1112124a44
https://doi.org/10.1161/strokeaha.116.013650

MicroRNA signatures in hereditary breast cancer

Autor: Sarai Palanca Suela, María José Juan Fita, Rosa Murria Estal, Dolors Sánchez-Izquierdo, Pascual Bolufer Gilabert, Ángel Segura Huerta, Zaida García-Casado, Eva Barragán González, Marta Llop García, Inmaculada de Juan Jiménez, Isabel Chirivella González, Ana Beatriz Sánchez Heras, Cecilia Egoavil Rojas

Publikováno v: BREAST CANCER RESEARCH AND TREATMENT
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

This study aims to identify signatures of miR associated with hereditary, BRCA1 or BRCA2 mutation positive breast cancer (BC), and non-hereditary BC, either sporadic (SBC) or non-informative (BRCAX). Moreover, we search for signatures associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e349cabcd1e0d311600cbf999d9cae
https://doi.org/10.1007/s10549-013-2723-7

[The new challenge in oncology: Next-generation sequencing and its application in precision medicine]

Autor: Adela Cañete, Pablo Berlanga, Dolors Sánchez-Izquierdo, José Cervera, María José Aparisi, Inés Calabria, José M. Millán, Victoria Castel, Laia Pedrola

Publikováno v: Anales de Pediatría (English Edition), Vol 85, Iss 5, Pp 273.e1-273.e7 (2016)

Precision medicine is an emerging approach for the diagnosis, treatment and prognosis of genetic diseases that enables clinicians to more accurately predict which treatment strategy will be optimal in a patient. The aim of Precision Medicine in Oncol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62af61c9a942574a20e2b8e150365f7b
https://pubmed.ncbi.nlm.nih.gov/27349697