Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Dolors Fernández-Forner"'
Autor:
Pilar Forns, Dolors Fernández-Forner, Natalia de la Figuera, Fernando Albericio, Joan C. Fernandez, Sandra Fiol
Publikováno v:
Letters in Organic Chemistry. 5:374-378
Autor:
Fernando Albericio, Joan-Carles Fernàndez, Aina Colombo, Natalia de la Figuera, Pilar Forns, Dolors Fernández-Forner
Publikováno v:
Tetrahedron Letters. 49:1569-1572
Diastereoselectivity in the oxidation of different 4-thiazolidinones was discussed. Alkylation of these compounds with benzyl bromide was also studied. The stereoselectivity obtained was interpreted by the presence of the sulfoxide.
Autor:
Fernando Albericio, Joan-Carles Fernàndez, Natalia de la Figuera, Pilar Forns, Dolors Fernández-Forner, Aina Colombo
Publikováno v:
Organic Letters. 9:4319-4322
Synthesis and applications of two new nonacid degradable linkers as an alternative to the Wang linker for solid-phase synthesis are described. Resin from linker 2 looks superior to linker 1 in terms of yields for both anchoring of the first building
Autor:
Joan-Carles Fernàndez, Laia Solé-Feu, Natalia de la Figuera, Fernando Albericio, Pilar Forns, Dolors Fernández-Forner
Publikováno v:
QSAR & Combinatorial Science. 25:961-965
Solid-phase N-amination of 2-aminopyridin-3/5-yl derivatives supported via an acid labile linker by hydroxylamine-based electrophilic NH 2 + equivalents is described. A comparison of aminating efficiency and stability between O-Mesitylenesulfonyl Hyd
Autor:
Pilar Forns, Dolors Fernández-Forner, Sandra Fiol, Joan-Carles Fernàndez, Fernando Albericio, Natalia de la Figuera
Publikováno v:
Synlett. 2006:1903-1907
Pictet-Spengler reactions of different α-amino acids in very mild conditions have been studied. Excellent yields were obtained by simply heating the free acids in alcoholic solvents, both in the presence and absence of one equivalent of Et 3 N. Howe
Perfluorous Solid-Phase Organic Synthesis (PF-SPOS) and IRORI Technology for Combinatorial Chemistry
Autor:
Alberto Ortega, Richard S. Roberts, Dolors Fernández-Forner, Montserrat Erra, Eloı́sa Navarro
Publikováno v:
QSAR & Combinatorial Science. 25:598-604
The use of perfluorous solvents in combination with IRORI technology and its application for the synthesis of combinatorial libraries is described. This methodology shows a clear advantage over standard solid-phase synthesis in IRORI MiniKans, becaus
Autor:
Natalia de la Figuera, Fernando Albericio, Joan-Carles Fernàndez, Aina Colombo, Pilar Forns, Dolors Fernández-Forner
Publikováno v:
QSAR & Combinatorial Science. 24:913-922
A convenient strategy (preliminary study, preproduction and production) for the solid-phase preparation of a library using 4-iodophenylalanine as a scaffold is described. The aromatic ring was first modified via the Suzuki reaction and the amino posi
Suzuki coupling reaction for the solid-phase preparation of 5-substituted nicotinic acid derivatives
Autor:
Pilar Forns, Dolors Fernández-Forner, Laia Solé-Feu, Joan-Carles Fernàndez, Natalia de la Figuera, Fernando Albericio
Publikováno v:
Tetrahedron Letters. 46:581-585
The application of the Suzuki coupling reaction to the preparation of small combinatorial libraries using 5-bromonicotinic acid as a scaffold onto three different types of solid support (Wang, Rink, and BAL resin) is described.
Autor:
Ruben Ventura, Joan-Carles Fernàndez, Marc Vendrell, Fernando Albericio, Francesc Yraola, Miriam Royo, Aina Colombo, A. Pilar Forns, Natalia de la Figuera, Dolors Fernández-Forner
Publikováno v:
QSAR & Combinatorial Science. 23:145-152
The preparation of amine and guanidine derivatives of phenylalaninamide and tryptophanamide as well as benzylamines from BAL, Rink-MBHA, and Rink resins has been performed. Cleavage of the target compound gave significant amounts of byproducts compou
Autor:
Natalia de la Figuera, Alberto Ortega, Sara Sevilla, Fernando Albericio, Pilar Forns, Montserrat Erra, Joan-Carles Fernàndez, Dolors Fernández-Forner
Publikováno v:
Tetrahedron Letters. 44:6907-6910
Although amino acids anchored through the amino function to BAL resins can not easily be released from the resin by treatment with neat trifluoroacetic acid, we have shown that secondary amines can be obtained from BAL resins using trifluoroacetic ac