Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dolores R. Brine"'
Autor:
Rochelle W. Tyl, John H. Butala, Robert A. Barter, Patricia A. Fail, John C. Seely, Melissa C. Marr, Christina B. Myers, Dolores R. Brine
Publikováno v:
Reproductive Toxicology. 18:241-264
Butyl benzyl phthalate (BBP) was administered in the diet at 0, 750, 3750, and 11,250 ppm ad libitum to 30 rats per sex per dose for two offspring generations, one litter/breeding pair/generation, through weaning of F2 litters. Adult F0 systemic toxi
Autor:
Patricia A. Fail, J. P. Van Miller, Dolores R. Brine, Rochelle W. Tyl, John C. Seely, Christina B. Myers, Melissa C. Marr
Publikováno v:
Regulatory Toxicology and Pharmacology. 30:81-95
Octylphenol (OP) is a commercial intermediate used primarily for the production of octylphenol polyethoxylate surfactants. To determine potential reproductive toxicity of OP, a two-generation reproduction study was conducted according to U.S. EPA OPP
Autor:
Dolores R. Brine, Richard T. Henrich, Rochelle W. Tyl, Christina B. Myers, John C. Seely, Melissa C. Marr, James M. Gerhart
Publikováno v:
Toxicological Sciences. 40:90-100
Tributyl phosphate (TBP) was tested for reproductive toxicity in rats. Thirty weanlings/sex (F0) were exposed to TBP in the diet ad libitum at 0, 200, 700, or 3000 ppm for 10 weeks and then randomly mated within groups for 3 weeks with continued expo
Autor:
Anne F. Gilliam, Rochelle W. Tyl, William E. Rinehart, Melissa C. Marr, Michael J. Derelanko, James M. Gerhart, John C. Seely, Dolores R. Brine, Christina B. Myers
Publikováno v:
Fundamental and Applied Toxicology. 31:149-161
Methylethyl ketoxime (CAS No. 96-29-7; MEKO; 2-butanone oxime), an antioxidant agent used in paints, resins, and adhesives, was tested for reproductive toxicity in a two-generation study with CD (Sprague–Dawley) rats. Thirty-eight-week-old rats/sex
Autor:
Nicholas H. Oberlies, Monroe E. Wall, Robert W. Handy, Dolores R. Brine, Mansukh C. Wani, Nam-Cheol Kim
Publikováno v:
Journal of Natural Products. 64:251-253
Three pyrrolizidine alkaloids, symlandine, symphytine, and echimidine (1-3), were isolated from the roots of Symphytum officinale using a one-step countercurrent chromatography procedure. The structures of 1-3 were confirmed by several spectroscopic
Autor:
Charles Sparacino, Robert W. Handy, Nicholas H. Oberlies, Monroe E. Wall, Mansukh C. Wani, Dolores R. Brine, Bradley J. Collins, Nam-Cheol Kim
Publikováno v:
Public health nutrition. 7(7)
Objectives:To determine the relative quantities of two hepatotoxic pyrrolizidine alkaloids, symphytine and echimidine, in teas prepared from comfrey leaves (Symphytum officinale), and to determine the potential contribution of the N-oxide forms of th
Autor:
Stuart Cagen, Patricia A. Fail, R. L. Joiner, Melissa C. Marr, Milan Veselica, Stephen Dimond, Tsai-Ying Chang, John H. Butala, Rochelle W. Tyl, John M. Waechter, Gisela D. Stropp, R. N. Shiotsuka, Christina B. Myers, Dolores R. Brine, John C. Seely, Alison R. Keimowitz, Brian F. Thomas
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 68(1)
Bisphenol A (BPA) was evaluated at concentrations of 0, 0.015, 0.3, 4.5, 75, 750, and 7500 ppm ( approximately 0.001, 0.02, 0.3, 5, 50, and 500 mg/kg/day of BPA) administered in the diet ad libitum to 30 CD((R)) Sprague-Dawley rats/sex/dose for 3 off
Autor:
Nicholas H Oberlies, Nam-Cheol Kim, Dolores R Brine, Bradley J Collins, Robert W Handy, Charles M Sparacino, Mansukh C Wani, Monroe E Wall
Publikováno v:
Public Health Nutrition; Oct2004, Vol. 7 Issue 7, p919-924, 6p
Publikováno v:
Clinical Pharmacology and Therapeutics. 32:635-641
Subeffective doses (0.5 mg) of 3H-phencyclidine (PCP) were given intravenously to three healthy men under two regimens designed to alkalinize or acidify their urine (oral sodium bicarbonate or ammonium chloride). The concentrations of PCP and its met
Publikováno v:
Clinical Pharmacology and Therapeutics. 31:635-641
Five men who smoked parsley cigarettes containing 100 micrograms of [3H]-phencyclidine hydrochloride (PCP.HCl) inhaled 69 +/- 5(SEM) % of the total radioactivity in the cigarette. Both PCP and its pyrolysis product, 1-phenylcyclohexene (PC), were fou