Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Dolores Ortiz"'
Autor:
Dulce C. Macias-Ceja, M. Teresa Mendoza-Ballesteros, María Ortega-Albiach, M. Dolores Barrachina, Dolores Ortiz-Masià
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
In inflammatory bowel disease (IBD), chronic inflammation in the gastrointestinal tract can lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged injury and inflammation can trigger the activation of fibroblasts an
Externí odkaz:
https://doaj.org/article/84f1fe7bc75f4e7fbd81ce2727527f54
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Chronic inflammation is often associated with fibrotic disorders in which an excessive deposition of extracellular matrix is a hallmark. Long-term fibrosis starts with tissue hypofunction and finally ends in organ failure. Intestinal fibrosis is not
Externí odkaz:
https://doaj.org/article/7d5d4085e1884421bfd0045db0817cf4
Autor:
Lluis Lis-López, Cristina Bauset, Marta Seco-Cervera, Dulce Macias-Ceja, Francisco Navarro, Ángeles Álvarez, Juan Vicente Esplugues, Sara Calatayud, Maria Dolores Barrachina, Dolores Ortiz-Masià, Jesús Cosín-Roger
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12936 (2023)
Intestinal fibrosis is a common complication that affects more than 50% of Crohn´s Disease (CD) patients. There is no pharmacological treatment against this complication, with surgery being the only option. Due to the unknown role of P2X7 in intesti
Externí odkaz:
https://doaj.org/article/e9054f54e6c24668bbf7926cd849c5ec
Autor:
Gonzalo Santos, Francisco González, Dolores Ortiz, José María Saiz, Maria Losurdo, Yael Gutiérrez, Fernando Moreno
Publikováno v:
Physics, Vol 3, Iss 3, Pp 655-663 (2021)
Structural color emerges from the interaction of light with structured matter when its dimension is comparable to the incident wavelength. The reflected color can be switched by controlling such interaction with materials whose properties can be chan
Externí odkaz:
https://doaj.org/article/e916aaca3f5d4eb19e93d85efb4a8144
Autor:
Dulce C. Macias-Ceja, Sandra Coll, Cristina Bauset, Marta Seco-Cervera, Laura Gisbert-Ferrándiz, Francisco Navarro, Jesus Cosin-Roger, Sara Calatayud, María D. Barrachina, Dolores Ortiz-Masia
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1093 (2022)
Background: Fibrosis is a common complication of Crohn’s disease (CD) in which macrophages play a central role. Epithelial-mesenchymal transition (EMT) and the WNT pathway have been associated with fibrosis. We aim to analyse the relevance of the t
Externí odkaz:
https://doaj.org/article/e012280dc62d4b5899a82b3b91e4f070
Autor:
Cristina Bauset, Lluis Lis-Lopez, Sandra Coll, Laura Gisbert-Ferrándiz, Dulce C. Macias-Ceja, Marta Seco-Cervera, Francisco Navarro, Juan V. Esplugues, Sara Calatayud, Dolores Ortiz-Masia, Maria D. Barrachina, Jesús Cosín-Roger
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 532 (2022)
Intestinal epithelial cells (IECs) constitute a defensive physical barrier in mucosal tissues and their disruption is involved in the etiopathogenesis of several inflammatory pathologies, such as Ulcerative Colitis (UC). Recently, the succinate recep
Externí odkaz:
https://doaj.org/article/03c4bdcc8e124ca5bb633d4ac1d4324f
Autor:
Fernando Alegre, Alberto Martí-Rodrigo, Miriam Polo, Dolores Ortiz-Masiá, Celia Bañuls, Marcello Pinti, Ángeles Álvarez, Nadezda Apostolova, Juan V. Esplugues, Ana Blas-García
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 109 (2022)
Drug-induced liver injury (DILI) constitutes a clinical challenge due to the incomplete characterization of the mechanisms involved and potential risk factors. Efavirenz, an anti-HIV drug, induces deleterious actions in hepatocytes that could underli
Externí odkaz:
https://doaj.org/article/b5679db1ed784a1b89c30fc34497cd05
Publikováno v:
Cells, Vol 9, Iss 11, p 2345 (2020)
G-protein-coupled receptors constitute the most diverse and largest receptor family in the human genome, with approximately 800 different members identified. Given the well-known metabolic alterations in cancer development, we will focus specifically
Externí odkaz:
https://doaj.org/article/3f139c90de324a97bce88a93fd8c5925
Autor:
Dolores Ortiz-Masiá, Laura Gisbert-Ferrándiz, Cristina Bauset, Sandra Coll, Céline Mamie, Michael Scharl, Juan V. Esplugues, Rafael Alós, Francisco Navarro, Jesús Cosín-Roger, María D. Barrachina, Sara Calatayud
Publikováno v:
Cells, Vol 9, Iss 5, p 1104 (2020)
The pathogenesis of Crohn’s disease-associated fibrostenosis and fistulas imply the epithelial-to-mesenchymal transition (EMT) process. As succinate and its receptor (SUCNR1) are involved in intestinal inflammation and fibrosis, we investigated the
Externí odkaz:
https://doaj.org/article/593bc16324b04ccfb711f32abf6ef593
Autor:
Laura Gisbert-Ferrándiz, Jesús Cosín-Roger, Carlos Hernández, Dulce C. Macias-Ceja, Dolores Ortiz-Masiá, Pedro Salvador, Juan V. Esplugues, Joaquín Hinojosa, Francisco Navarro, Sara Calatayud, María D. Barrachina
Publikováno v:
Nutrients, Vol 12, Iss 4, p 973 (2020)
Vitamin D (VD) deficiency has been associated to Crohn’s disease (CD) pathogenesis, and the exogenous administration of VD improves the course of the disease, but the mechanistic basis of these observations remains unknown. Vitamin D receptor (VDR)
Externí odkaz:
https://doaj.org/article/587698ab50bf424b96ede3ddef7cb9ec