The role of the eosinophil-selective chemokine, eotaxin, in allergic and non-allergic airways inflammation

Autor: Dolores M Conroy, Alison A Humbles, Sara M Rankin, Roger T Palframan, Paul D Collins, David A Griffiths-Johnson, Peter J Jose, Timothy J Williams

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 92, Pp 183-191 (1997)

Blood eosinophilia and tissue infiltration by eosinophils are frequently observed in allergic inflammation and parasitic infections. This selective accumulation of eosinophils suggested the existence of endogenous eosinophil-selective chemoattractant

Externí odkaz: https://doaj.org/article/d426755c424140f5829a1315f0dc482c

CCR4 blockade does not inhibit allergic airways inflammation

Autor: Ian Sabroe, Martin R. Hodge, Timothy J. Williams, Louise A. Jopling, Dolores M. Conroy, Clare M. Lloyd, David P. Andrew, James E. Pease

Publikováno v: Journal of Leukocyte Biology. 74:558-563

The CC chemokine receptor 4 (CCR4) shows selectivity for the recruitment of memory T cell subsets, including those of the T helper cell type 2 (Th2) phenotype. In humans, CCR4+ T cells are recruited to the asthmatic lung in response to allergen chall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85486c462220bd5ad2c49fa1a0cdfdd5
https://doi.org/10.1189/jlb.0103030

[Untitled]

Autor: Pierre Sirois, Dolores M. Conroy

Publikováno v: Inflammation. 23:437-448

The effects of an intravenous injection (i.v.) of Sephadex beads (20 mg kg−1) were examined on bronchial responsiveness to ACh (1–200 μg kg−1 i.v.) as well as on cell accumulation in guinea-pig lung. Bronchial hyperreactivity to ACh, measured

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca1e98ca8f82bf964c1b98f149d33db4
https://doi.org/10.1023/a:1021913009742

The role of the eosinophil-selective chemokine, eotaxin, in allergic and non-allergic airways inflammation

Autor: Sara M. Rankin, David A. Griffiths-Johnson, Alison A. Humbles, Paul D. Collins, Roger T. Palframan, Timothy J. Williams, Dolores M. Conroy, Peter J. Jose

Publikováno v: Memórias do Instituto Oswaldo Cruz, Volume: 92 Supplement 2, Pages: 183-191, Published: DEC 1997
Memórias do Instituto Oswaldo Cruz., Vol 92, Pp 183-191 (1997)
Memórias do Instituto Oswaldo Cruz., Vol 92, Iss suppl.2, Pp 183-191 (1997)

Blood eosinophilia and tissue infiltration by eosinophils are frequently observed in allergic inflammation and parasitic infections. This selective accumulation of eosinophils suggested the existence of endogenous eosinophil-selective chemoattractant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ac98b4252d5c054d0b23246d3f1d9d
https://doi.org/10.1590/s0074-02761997000800024

Inhibition by rapamycin of leukocyte migration and bronchial hyperreactivity induced by injection of Sephadex beads to guinea-pigs

Autor: Pierre Sirois, Dolores M. Conroy, Janetti Nogueira de Francischi, K. Maghni

Publikováno v: British Journal of Pharmacology. 110:1381-1386

1. The effect of rapamycin (0.001 to 5 mg kg-1) on the increased leukocyte counts in bronchoalveolar lavage (BAL) fluid and hyperreactivity of isolated bronchial strips to histamine and acetylcholine (ACh) was studied following the intravenous inject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671cd18317887c70096519a4504831ef
https://doi.org/10.1111/j.1476-5381.1993.tb13973.x