Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Dolores B Njoku"'
Autor:
Chloe Thomas, Dolores B. Njoku
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Males are at higher risk for developing metabolic dysfunction-associated steatohepatitis (MASH) than females; however, mechanisms mediating sexual dimorphism in MASH development are not completely understood. Nutrition-based mouse models suggest that
Externí odkaz:
https://doaj.org/article/73f05f117a7f4a7f8cf51824bc51d591
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61186 (2013)
Immune-mediated, drug-induced liver injury (DILI) triggered by drug haptens is more prevalent in women than in men. However, mechanisms responsible for this sex bias are not clear. Immune regulation by CD4+CD25+FoxP3+ regulatory T-cells (Tregs) and 1
Externí odkaz:
https://doaj.org/article/0ba8af0d093f4326ba1eb7466916aa3a
Autor:
Elisa K. McCarthy, Amanda Vakos, Merylin Cottagiri, Joel J. Mantilla, Lakshmi Santhanam, David L. Thomas, L. Mario Amzel, Noel R. Rose, Dolores B. Njoku
Publikováno v:
mSphere, Vol 3, Iss 6 (2018)
Externí odkaz:
https://doaj.org/article/cf3b6b1b7b2b464785a173f357f94dc1
Autor:
Elisa K. McCarthy, Amanda Vakos, Merylin Cottagiri, Joel J. Mantilla, Lakshmi Santhanam, David L. Thomas, L. Mario Amzel, Noel R. Rose, Dolores B. Njoku
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Cytochrome p4502E1 (CYP2E1) autoantibodies are biomarkers for drug-induced hepatitis and chronic hepatitis C. However, major histocompatibility-restricted CYP2E1 epitopes associated with these diseases have not been identified. We hypothesiz
Externí odkaz:
https://doaj.org/article/ceead6170a3a4ddbbf05034204357f43
Publikováno v:
Current opinion in lipidology. 33(5)
Nonalcoholic steatohepatitis (NASH) is a multisystem disease that affects not only the liver but also heart, pancreas, and kidney. We currently lack a comprehensive understanding of mechanisms responsible for the development of NASH-associated cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2928ced2b4eafdc2ed9d9766902c2613
https://pubmed.ncbi.nlm.nih.gov/35942818
https://pubmed.ncbi.nlm.nih.gov/35942818
Autor:
Andrew B. Harris, Caleb Gottlich, Dolores B. Njoku, Majd Marrache, Amit Jain, Paul D. Sponseller, Micheal Raad, Richard L. Skolasky, Varun Puvanesarajah
Publikováno v:
Spine Deformity. 8:965-973
Retrospective review.To identify national trends in postoperative opioid prescribing practices after posterior spinal fusion (PSF) in patients with adolescent idiopathic scoliosis (AIS). Opioids are an important component of pain management after PSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57cdab73aad91b2c20131fd5d0acc04
https://doi.org/10.1007/s43390-020-00127-z
https://doi.org/10.1007/s43390-020-00127-z
Autor:
Wei Dong Gao, Shun Ishiyama, Xin Guo, Lakshmi Santhanam, Kathleen L. Gabrielson, Dolores B. Njoku, Haoran Wang, Sananda Pai
Publikováno v:
Cell Mol Immunol
Immune-mediated, drug-induced hepatitis is a rare complication of halogenated volatile anesthetic administration. IL-4-regulated Th2-polarized reactions initiate this type and other types of hepatitis, while the mechanisms that regulate the severity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b72eef55c5ff9fa4e6bdec9c5ea523f
https://europepmc.org/articles/PMC8322313/
https://europepmc.org/articles/PMC8322313/
Autor:
Paul D. Sponseller, Richard L. Skolasky, Andrew B. Harris, Varun Puvanesarajah, Majd Marrache, Micheal Raad, Dolores B. Njoku, Amit Jain
Publikováno v:
Journal of Pediatric Orthopaedics. 40:e629-e633
BACKGROUND The incidence of emergency department (ED) visits after posterior spinal fusion (PSF) in adolescent idiopathic scoliosis (AIS) patients is not well known. We hypothesize that the majority of ED visits are related to constipation and pain i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74343ce38ce5d4dcbc79e7267082c97
https://doi.org/10.1097/bpo.0000000000001444
https://doi.org/10.1097/bpo.0000000000001444
Autor:
Amanda Nicoll, David Moore, Francesco Amico, Adam Doyle, Brad Hockey, Siddharth Sood, Bridget Bishop, Dolores B. Njoku, Alexandra Gorelik, Nicholas Hannah, Danny Liew
Publikováno v:
Alimentary Pharmacology & Therapeutics. 49:940-951
Background Volatile anaesthetics are known to cause drug-induced liver injury, a hepatotoxic reaction characterised by antibodies to trifluoroacetylated lipid and protein adducts and cytochrome p450 2E1. The incidence of volatile anaesthetic drug-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7845552daf94a6516a661a63a11fa2
https://doi.org/10.1111/apt.15168
https://doi.org/10.1111/apt.15168
Autor:
Sananda Pai, Dolores B. Njoku
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2717, p 2717 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2717, p 2717 (2021)
Hypoxia-induced mitogenic factor (HIMF), which is also known as resistin-like molecule α (RELM-α), found in inflammatory zone 1 (FIZZ1), or resistin-like alpha (retlna), is a cysteine-rich secretory protein and cytokine. HIMF has been investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f92493784e23b3bb07dc64fa8bc30f
http://europepmc.org/articles/PMC7962531
http://europepmc.org/articles/PMC7962531