Zobrazeno 1 - 10 of 613 pro vyhledávání: '"Dolle RE"'
1
Akademický článek
An orally available compound suppresses glucagon hypersecretion and normalizes hyperglycemia in type 1 diabetes.
Autor: Asadi F; Department of Cell Biology and Physiology and., Gunawardana SC; Department of Cell Biology and Physiology and., Dolle RE; Center for Drug Discovery, Washington University School of Medicine, St. Louis, Missouri, USA., Piston DW; Department of Cell Biology and Physiology and.
Publikováno v: JCI insight [JCI Insight] 2024 Jan 23; Vol. 9 (2). Date of Electronic Publication: 2024 Jan 23.
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2
Akademický článek
Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington's disease neurodegeneration.
Autor: Lee SW; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Biomedical Sciences, Mercer University School of Medicine, Columbus, GA, USA., Oh YM; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Biomedical Sciences, Mercer University School of Medicine, Columbus, GA, USA., Victor MB; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Yang Y; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Chen S; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Strunilin I; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Dahiya S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Dolle RE; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA., Pak SC; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Silverman GA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Perlmutter DH; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Yoo AS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA. yooa@wustl.edu.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA. yooa@wustl.edu.
Publikováno v: Nature aging [Nat Aging] 2024 Jan; Vol. 4 (1), pp. 95-109. Date of Electronic Publication: 2023 Dec 08.
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3
Akademický článek
Development of ADS051, an oral, gut-restricted, small molecule neutrophil modulator for the treatment of neutrophil-mediated inflammatory diseases.
Autor: Murphy CK; Adiso Therapeutics, Inc. (formerly Bacainn Therapeutics, Inc.), Concord, MA, USA., Dixit B; Adiso Therapeutics, Inc. (formerly Bacainn Therapeutics, Inc.), Concord, MA, USA., Oleson FB; Independent Consultant, Carlisle, MA, USA., Dolle RE; Medicine Inventions LLC, Eureka, MO, USA., Farquhar R; Adiso Therapeutics, Inc. (formerly Bacainn Therapeutics, Inc.), Concord, MA, USA., McCormick BA; Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Program in Microbiome Dynamics, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Publikováno v: FEBS open bio [FEBS Open Bio] 2023 Aug; Vol. 13 (8), pp. 1434-1446. Date of Electronic Publication: 2023 Jul 10.
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4
Akademický článek
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases.
Autor: Docherty CA; Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research Clayton VIC Australia.; Department of Molecular and Translational Sciences Monash University Clayton VIC Australia., Fernando AJ; University of Edinburgh Centre for Inflammation Research Queen's Medical Research Institute, Edinburgh BioQuarter Edinburgh UK., Rosli S; Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research Clayton VIC Australia.; Department of Molecular and Translational Sciences Monash University Clayton VIC Australia., Lam M; Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research Clayton VIC Australia.; Department of Molecular and Translational Sciences Monash University Clayton VIC Australia., Dolle RE; Department of Biochemistry and Molecular Biophysics Washington University School of Medicine St. Louis MO USA., Navia MA; Hub-Bio Strategic Advising Lexington MA USA., Farquhar R; Adiso Therapeutics Concord MA USA., La France D; Adiso Therapeutics Concord MA USA., Tate MD; Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research Clayton VIC Australia.; Department of Molecular and Translational Sciences Monash University Clayton VIC Australia., Murphy CK; Adiso Therapeutics Concord MA USA., Rossi AG; University of Edinburgh Centre for Inflammation Research Queen's Medical Research Institute, Edinburgh BioQuarter Edinburgh UK., Mansell A; Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research Clayton VIC Australia.; Department of Molecular and Translational Sciences Monash University Clayton VIC Australia.; Adiso Therapeutics Concord MA USA.
Publikováno v: Clinical & translational immunology [Clin Transl Immunology] 2023 Jun 22; Vol. 12 (6), pp. e1455. Date of Electronic Publication: 2023 Jun 22 (Print Publication: 2023).
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5
Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease.
Autor: Lee SW; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Oh YM; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Victor MB; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Strunilin I; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Chen S; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Dahiya S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110., Dolle RE; Department of Biochemistry, Washington University School of Medicine, St. Louis, MO 63110, USA., Pak SC; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Silverman GA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Perlmutter DH; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Yoo AS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Publikováno v: Research square [Res Sq] 2023 May 09. Date of Electronic Publication: 2023 May 09.
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6
Akademický článek
Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy.
Autor: Oh YM; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Lee SW; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Kim WK; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Chen S; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Church VA; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Cates K; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA., Li T; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA., Zhang B; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA., Dolle RE; Department of Biochemistry, Washington University School of Medicine, St. Louis, MO, USA., Dahiya S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Pak SC; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Silverman GA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Perlmutter DH; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Yoo AS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA. yooa@wustl.edu.; Center of Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA. yooa@wustl.edu.
Publikováno v: Nature neuroscience [Nat Neurosci] 2022 Nov; Vol. 25 (11), pp. 1420-1433. Date of Electronic Publication: 2022 Oct 27.
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7
Correction to "Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondrial Diseases".
Autor: Dang X, Zhang L, Franco A, Li J, Rocha AG, Devanathan S, Dolle RE, Bernstein PR, Dorn GW 2nd
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 10086. Date of Electronic Publication: 2020 Aug 21.
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8
Akademický článek
Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondrial Diseases.
Autor: Dang X; Department of Cardiology, The First Affiliated Hospital of Xi'an Jiao Tong University, Xi'an 710061, Shaanxi, China.; Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Missouri 63110, United States., Zhang L; Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Missouri 63110, United States., Franco A; Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Missouri 63110, United States.; Mitochondria in Motion, Inc. 4340 Duncan Avenue, Suite 216, St. Louis, Missouri 63110, United States., Li J; Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Missouri 63110, United States., Rocha AG; Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Missouri 63110, United States., Devanathan S; Mitochondria in Motion, Inc. 4340 Duncan Avenue, Suite 216, St. Louis, Missouri 63110, United States., Dolle RE; Mitochondria in Motion, Inc. 4340 Duncan Avenue, Suite 216, St. Louis, Missouri 63110, United States.; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S. Euclid Ave. St. Louis, Missouri 63110, United States., Bernstein PR; Harrington Discovery Institute at University Hospitals, 11407 Euclid Ave, Cleveland, Ohio 44106, United States., Dorn GW 2nd; Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Missouri 63110, United States.; Mitochondria in Motion, Inc. 4340 Duncan Avenue, Suite 216, St. Louis, Missouri 63110, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Jul 09; Vol. 63 (13), pp. 7033-7051. Date of Electronic Publication: 2020 Jun 18.
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9
Akademický článek
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10
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