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Autor:
Dolev Katz, Rajendar Kandhikonda, Orna Ernst, Roy Weinstain, Olga Bernadsky, Anna Lilja, Iain D. C. Fraser, Hussein Aeed, Joram Wardi, Iris Ben-Dror, Idan Ben-Nachum, Sebastian Katz, Tsaffrir Zor, Alexander Biro, Yona Avni
Publikováno v:
Digestive diseases and sciences. 63(12)
Concanavalin A is known to activate T cells and to cause liver injury and hepatitis, mediated in part by secretion of TNFα from macrophages. Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors have been shown to prevent tissue damage in various animal