Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Dokyun Na"'
Autor:
Daeahn Cho, Myeong-Sang Yu, Jeongyoon Shin, Jingyu Lee, Yubin Kim, Hoon-Chul Kang, Se Hee Kim, Dokyun Na
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss S2, Pp 1-9 (2024)
Abstract Background Epilepsy, a chronic brain disorder characterized by abnormal brain activity that causes seizures and other symptoms, is typically treated using anti-epileptic drugs (AEDs) as the first-line therapy. However, due to the variations
Externí odkaz:
https://doaj.org/article/46bc8951cf4c4a839acfdfc13e3e88e4
Autor:
Dokyun Na, Do‐Hwan Lim, Jae‐Sang Hong, Hyang‐Mi Lee, Daeahn Cho, Myeong‐Sang Yu, Bilal Shaker, Jun Ren, Bomi Lee, Jae Gwang Song, Yuna Oh, Kyungeun Lee, Kwang‐Seok Oh, Mi Young Lee, Min‐Seok Choi, Han Saem Choi, Yang‐Hee Kim, Jennifer M Bui, Kangseok Lee, Hyung Wook Kim, Young Sik Lee, Jörg Gsponer
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)
Abstract The accumulation of misfolded and aggregated proteins is a hallmark of neurodegenerative proteinopathies. Although multiple genetic loci have been associated with specific neurodegenerative diseases (NDs), molecular mechanisms that may have
Externí odkaz:
https://doaj.org/article/189ad69333ab48fca215c7cdd4f22dce
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S9, Pp 1-10 (2022)
Abstract Background G-protein coupled receptors (GPCRs) sense and transmit extracellular signals into the intracellular machinery by regulating G proteins. GPCR malfunctions are associated with a variety of signaling-related diseases, including cance
Externí odkaz:
https://doaj.org/article/49fa84c01cc04d0e89e900368aece850
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Toxic heavy metal accumulation is one of anthropogenic environmental pollutions, which poses risks to human health and ecological systems. Conventional heavy metal remediation approaches rely on expensive chemical and physical processes leading to th
Externí odkaz:
https://doaj.org/article/905492eea6ec4f50959b411face910df
Autor:
Jae Gwang Song, Myeong-Sang Yu, Bomi Lee, Jingyu Lee, Su-Hee Hwang, Dokyun Na, Hyung Wook Kim
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1097-1110 (2022)
For a long time, the central nervous system was believed to be the only regulator of cognitive functions. However, accumulating evidence suggests that the composition of the microbiome is strongly associated with brain functions and diseases. Indeed,
Externí odkaz:
https://doaj.org/article/e7b69bb8f1cf40c3a80ca49fbdc547fd
Autor:
Hyang-Mi Lee, Jun Ren, Myeong-Sang Yu, Hyunjoo Kim, Woo Young Kim, Junhao Shen, Seung Min Yoo, Seong-il Eyun, Dokyun Na
Publikováno v:
Biotechnology for Biofuels, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Background As methane is 84 times more potent than carbon dioxide in exacerbating the greenhouse effect, there is an increasing interest in the utilization of methanotrophic bacteria that can convert harmful methane into various value-added
Externí odkaz:
https://doaj.org/article/483c0706133f4ef6885765b9040a9b44
Autor:
Sanghyun Park, Jeong-Eun Yoo, Gyu-Bum Yeon, Jin Hee Kim, Jae Souk Lee, Sung Kyoung Choi, Young-Gi Hwang, Chan Wook Park, Myung Soo Cho, Jongwan Kim, Dokyun Na, Hyung Wook Kim, Dae-Sung Kim, Dong-Wook Kim
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Parkinson’s disease (PD) is a movement disorder caused by progressive degeneration of the midbrain dopaminergic (mDA) neurons in the substantia nigra pars compacta (SNc). Despite intense research efforts over the past decades, the etiology
Externí odkaz:
https://doaj.org/article/414ea96a254c4bf3ab483124287001e0
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S11, Pp 1-9 (2021)
Abstract Background Lately, high-throughput RNA sequencing has been extensively used to elucidate the transcriptome landscape and dynamics of cell types of different species. In particular, for most non-model organisms lacking complete reference geno
Externí odkaz:
https://doaj.org/article/8acc77d005424864abf5aa66433442d2
Publikováno v:
Journal of Biological Engineering, Vol 15, Iss 1, Pp 1-9 (2021)
Abstract Escherichia coli is a widely used platform for metabolic engineering due to its fast growth and well-established engineering techniques. However, there has been a demand for faster-growing E. coli for higher production of desired substances.
Externí odkaz:
https://doaj.org/article/40f31cb566a14c6e9a3bacce3e4052f8
Autor:
Hyang-Mi Lee, Jun Ren, Kha Mong Tran, Byeong-Min Jeon, Won-Ung Park, Hyunjoo Kim, Kyung Eun Lee, Yuna Oh, Myungback Choi, Dae-Sung Kim, Dokyun Na
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Lee et al. construct a cell-penetrating peptides (CPP) library and identify CPPs that can penetrate bacterial cells with minimum or no impact on cell viability. For the identified top CPP candidates, their abilities to deliver macromolecules such as
Externí odkaz:
https://doaj.org/article/1314e57b090f4bf9a37650f6a651bd3e