Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Dohoon Lee"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1715-1724 (2024)
Multi-gene assays have been widely used to predict the recurrence risk for hormone receptor (HR)-positive breast cancer patients. However, these assays lack explanatory power regarding the underlying mechanisms of the recurrence risk. To address this
Externí odkaz:
https://doaj.org/article/1710448ba511484597734131807696a2
Autor:
Sung-Yeon Hwang, Hyewon Kim, Danielle Denisko, Boxun Zhao, Dohoon Lee, Jiseok Jeong, Jinuk Kim, Kiwon Park, Junhyun Park, Dongjoon Jeong, Sehong Park, Hee-Jung Choi, Sun Kim, Eunjung Alice Lee, Kwangseog Ahn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Genetic parasites, including viruses and transposons, exploit components from the host for their own replication. However, little is known about virus-transposon interactions within host cells. Here, we discover a strategy where human cytome
Externí odkaz:
https://doaj.org/article/4cb8ca1588cc4128a8050be8b240bfed
Publikováno v:
Archives of Metallurgy and Materials, Vol vol. 69, Iss No 1, Pp 135-139 (2024)
A powder-bed-based additive manufacturing process called electron beam melting (EBM) is defined by high temperature gradients during solidification, which produces an extremely fine microstructure compared to the traditional cast material. However, p
Externí odkaz:
https://doaj.org/article/5fdee4235d6548c4b9178ebb6a4b5585
Autor:
Hyundong Yoon, Dohoon Lee, Seulki Song, Bonil Koo, Jihyun Park, Tae Kon Kim, Sun Kim, Sheehyun Kim, Junshik Hong, Ja Min Byun, Dong‐Yeop Shin, Inho Kim, Youngil Koh, Sung‐Soo Yoon
Publikováno v:
Cancer Medicine, Vol 13, Iss 18, Pp n/a-n/a (2024)
Abstract Background Lysosomal dysfunction (LD) impacts cytokine regulation, inflammation, and immune responses, influencing the development and progression of cancer. Inflammation is implicated in the pathogenesis of myeloproliferative neoplasm (MPN)
Externí odkaz:
https://doaj.org/article/ef743f566c3847958966a4db604dfb3b
Autor:
Dohoon Lee, Sangwoo Park, Chan-Hee Lee, Hyun-Uk Hong, Jongyeong Oh, Tae-Yeong So, Woo-Sung Kim, Dongyi Seo, Jeongho Han, Se-Hyun Ko, Byoungsoo Lee
Publikováno v:
Journal of Materials Research and Technology, Vol 28, Iss , Pp 2410-2419 (2024)
This study explored the correlation between microstructure and mechanical properties in additively manufactured Inconel 718 superalloys with low and high electron beam (EB) currents. The relative densities of the as-built Inconel 718 superalloys with
Externí odkaz:
https://doaj.org/article/def8efe644fd4764b155d6b9f46a83b3
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract To respond to the external environmental changes for survival, bacteria regulates expression of a number of genes including transcription factors (TFs). To characterize complex biological phenomena, a biological system-level approach is nece
Externí odkaz:
https://doaj.org/article/4095fc0083b147e482e59f1e5f63bc18
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Existing deep learning-based approaches for the prediction of gene expression by histone modifications (HMs) can only focus on narrow and linear genomic regions around promoters. Here, the authors address these problems by developing a transformer-ba
Externí odkaz:
https://doaj.org/article/19fb42ca3e0e421ebe331d98c2361756
Autor:
Dohoon Lee, Sun Kim
Publikováno v:
Clinical and Experimental Pediatrics, Vol 65, Iss 5, Pp 239-249 (2022)
Cells survive and proliferate through complex interactions among diverse molecules across multiomics layers. Conventional experimental approaches for identifying these interactions have built a firm foundation for molecular biology, but their scalabi
Externí odkaz:
https://doaj.org/article/a895ab1103704cbfa8eb118a9adad1ee
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 3, p e1010946 (2023)
Phased DNA methylation states within bisulfite sequencing reads are valuable source of information that can be used to estimate epigenetic diversity across cells as well as epigenomic instability in individual cells. Various measures capturing the he
Externí odkaz:
https://doaj.org/article/c1cdbe64334e4b6eb79ba89e54d15edf
Autor:
Chang-Seop Shin, Truong Do, Dohoon Lee, Tae-Yeong So, Se-Hyun Ko, Haseung Chung, Patrick Kwon
Publikováno v:
Materials & Design, Vol 224, Iss , Pp 111343- (2022)
The mechanical properties of the parts produced by binder jet printing (BJP) are often considerably inferior to those of the parts produced by traditional manufacturing processes because BJP parts retain at best about 95% of theoretical density after
Externí odkaz:
https://doaj.org/article/e17b48de5bf145e5a939224eed50daa4