Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dohan Weeraratne"'
Autor:
Raju Subramanian, Hongjie Deng, Michael Serenko, M. Benjamin Hock, Dohan Weeraratne, Benjamin M. Wu, Bethlyn Sloey, Mark A. Kroenke
Publikováno v:
Journal of Immunological Methods. 445:37-44
The immunogenicity risk assessment and bioanalytical strategy for novel therapeutics should account for both unique biophysical properties and potential consequences of immunogenicity. When assessing the immunogenicity risk of etelcalcetide, a peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718313f79cd3460738bf11f15ada8c3a
https://doi.org/10.1016/j.jim.2017.03.005
https://doi.org/10.1016/j.jim.2017.03.005
Publikováno v:
Journal of Immunological Methods. 396:44-55
As with other protein therapeutics, trebananib (AMG 386), an investigational peptide Fc-fusion protein ("peptibody") that inhibits angiogenesis by neutralizing the interaction of angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2) with the Tie2 receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a62e8b172611a7c567e3134ea6bf400
https://doi.org/10.1016/j.jim.2013.07.010
https://doi.org/10.1016/j.jim.2013.07.010
Patients treated with erythropoietin-based erythropoiesis-stimulating agents (ESAs) can develop a rare but life-threatening condition called antibody-mediated pure red cell aplasia (amPRCA). The antibody characteristics in a nephrology patient with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3b919170cccdf7f793a541d9ad18f4
https://europepmc.org/articles/PMC3535764/
https://europepmc.org/articles/PMC3535764/
Autor:
Jacqueline Wright, Arunan Kaliyaperumal, Alin Chen, Marta Starcevic, Chi-Yuan Wu, Dohan Weeraratne, Kathy Zhang, Shalini Gupta, Juan Jose Perez-Ruixo, Jason J. Pennucci, Bing-Bing Yang, Steven J. Swanson, Narendra Chirmule
Publikováno v:
BMC Clinical Pharmacology
Background Panitumumab is a fully human antibody against the epidermal growth factor receptor that is indicated for the treatment of metastatic colorectal cancer (mCRC) after disease progression on standard chemotherapy. The purpose of this analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931991a469c6b2fb16399e1ba27787f5
https://doi.org/10.1186/1472-6904-11-17
https://doi.org/10.1186/1472-6904-11-17
Autor:
Dan Mytych, Danika Wullner, Dohan Weeraratne, Suzanna M. Tatarewicz, Steven J. Swanson, Michael Moxness, Nancy Murakami, Eugen Koren, Vibha Jawa
Publikováno v:
Clinical chemistry. 51(10)
Monitoring the immune response against human therapeutic monoclonal antibodies is an important component of preclinical and clinical trials to assess drug exposure, efficacy, and safety (1)(2). Detection of antibodies (analyte) directed against thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f543b22c8794c32fb9d2185e7b7f45
https://pubmed.ncbi.nlm.nih.gov/16299896
https://pubmed.ncbi.nlm.nih.gov/16299896
Autor:
Kinnari Pandya, Vibha Jawa, Steven J. Swanson, Narendra Chirmule, Danika Wullner, Steven Yu, Kevin Salyers, Dohan Weeraratne
Publikováno v:
Clinical Immunology. 135:S107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884251d2c9f942cb3ac546dd63e7ccc7
https://doi.org/10.1016/j.clim.2010.03.322
https://doi.org/10.1016/j.clim.2010.03.322