Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Doh-Yeel Lee"'
Autor:
Yuli Wang, Derek James Sheehan, Cornel Catana, Doh-Yeel Lee, Amy M. Delaney, Lisa A. Perrin, Fang Sun, Jeff Ohren, Frank Schwende, Kevin J. Filipski, Patrick I. McConnell, Jeffrey T. Kohrt, Noel A. Powell, Michael Kaufman, Francis Bourbonais, Huifen Chen, Jeremy E. Edmunds
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:190-193
We report the discovery of a novel series of spiroindoline-based inhibitors of Sky kinase that bind in the ATP-binding site and exhibit high levels of kinome selectivity through filling the Ala571-subpocket. These inhibitors exhibit moderate oral bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0525eacb86f519d2a615c9d6eaf5f300
https://doi.org/10.1016/j.bmcl.2011.11.036
https://doi.org/10.1016/j.bmcl.2011.11.036
Autor:
Don Emerson, Doh-Yeel Lee, Venkataraman Thanabal, Michael Melnick, J. Richard Miller, Ronald W. Sarver, Jeff Ohren, Manjinder S. Lall, Charles Francis Donovan
Publikováno v:
Chemical Biology & Drug Design. 75:444-454
High-throughput screening is utilized by pharmaceutical researchers and, increasingly, academic investigators to identify agents that act upon enzymes, receptors, and cellular processes. Screening hits include molecules that specifically bind the tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b214fe8e405df9a95986c60e3e95b5b2
https://doi.org/10.1111/j.1747-0285.2010.00957.x
https://doi.org/10.1111/j.1747-0285.2010.00957.x
Publikováno v:
Toxicology and Applied Pharmacology. 176:118-126
Fumonisins are a family of mycotoxins produced by Fusarium moniliforme, which is the most common mold found on corn throughout the world. These compounds are both toxic and carcinogenic for animals, and perhaps humans, with the kidney being the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb333e119f69a8defb8f42d1d449eac
https://doi.org/10.1006/taap.2001.9188
https://doi.org/10.1006/taap.2001.9188
Isolation and characterization of mammary cDNA differentially expressed in lethal milk mutation mice
Publikováno v:
The Journal of Trace Elements in Experimental Medicine. 14:371-382
Lethal milk (lm) mutation in C57BL/6J inbred mice results in the reduction of zinc content in the milk and causes fatal neonatal zinc deficiency. Zinc injection to lm pups after birth helps them to overcome severe neonatal zinc deficiency and to main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7646fc4dd8b12b6175b19783f329e6ea
https://doi.org/10.1002/jtra.1048
https://doi.org/10.1002/jtra.1048
Autor:
J Richard, Miller, Venkataraman, Thanabal, Michael M, Melnick, Manjinder, Lall, Charles, Donovan, Ronald W, Sarver, Doh-Yeel, Lee, Jeff, Ohren, Don, Emerson
Publikováno v:
Chemical biologydrug design. 75(5)
High-throughput screening is utilized by pharmaceutical researchers and, increasingly, academic investigators to identify agents that act upon enzymes, receptors, and cellular processes. Screening hits include molecules that specifically bind the tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8628c4ffe85dfcaae977426763a0830
https://pubmed.ncbi.nlm.nih.gov/20486930
https://pubmed.ncbi.nlm.nih.gov/20486930
Publikováno v:
Nutrition Research. 10:1005-1014
The objective of this study was to examine the effects of growth or differences in sex on Mn metabolism of rats fed diets deficient or adequate in Mn. Weanling male and female rats were fed diets containing less than 1 mg Mn/kg (MnD) or 47 mg Mn/kg d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab0743e2477bc11580b5de744d8f8482
https://doi.org/10.1016/s0271-5317(05)80042-9
https://doi.org/10.1016/s0271-5317(05)80042-9
Publikováno v:
The Journal of nutrition. 122(12)
The response of erythrocyte metallothionein to dietary zinc in human subjects was evaluated in a controlled metabolic protocol including standard indices of zinc status. Fifteen male subjects, age 27 +/- 3.6 y, participated in a 90-d, four-phase stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422ab28b49ac3999fa2238c3d41c8f1d
https://pubmed.ncbi.nlm.nih.gov/1453226
https://pubmed.ncbi.nlm.nih.gov/1453226
Publikováno v:
Trace Elements in Clinical Medicine ISBN: 9784431681229
In this paper we briefly summarize the evidence supporting the view that zinc acetate is an excellent, fully efficaceous, non-toxic therapy for the maintenance treatment of Wilson’s disease. The recommended dose is 50 mg three times per day with ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0068c42f4eed4e18dbc7be1934e68bc8
https://doi.org/10.1007/978-4-431-68120-5_38
https://doi.org/10.1007/978-4-431-68120-5_38
Autor:
Doh-Yeel Lee, Phyllis E. Johnson
Publikováno v:
Experimental Biology and Medicine. 190:211-216
Rats were fed diets containing either soy protein or casein and different levels of manganese, methionine, phytic acid, or arginine for 7 days and then fed test meals labeled with 2 microCi of 54Mn after an overnight fast. Retention of 54Mn in each r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5d7161f86a3df0ef1afb7b907396fd
https://doi.org/10.3181/00379727-190-42852
https://doi.org/10.3181/00379727-190-42852
Publikováno v:
The Journal of nutrition. 118(6)
The objective of this study was to evaluate the effect of phytic acid on copper (Cu) bioavailability. Male weanling rats were fed a Cu-deficient diet (less than 1.0 micrograms/g) for 4 wk and then were divided into 12 groups (n = 8) in a factorial de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d75abfaee81ec64ed6ea09a181a8f43
https://pubmed.ncbi.nlm.nih.gov/3373335
https://pubmed.ncbi.nlm.nih.gov/3373335