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pro vyhledávání: '"Dodecameric protein"'
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Autor:
Zonghai Chen, Pengjiao Ma, Tao Luo, Lang Bao, Wei Liao, Liang Ge, Rongchuan Zhao, Xinyan Wang
Publikováno v:
Microbial Pathogenesis. 155:104890
Tuberculosis (TB) is a chronic infectious disease that creates a heavy medical burden worldwide. The only approved vaccine, Bacillus Calmette-Guerin (BCG), cannot fully protect adolescents and adults from TB. Therefore, there is an urgent need to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a134948b1394c41a884508f4d429ae7
https://doi.org/10.1016/j.micpath.2021.104890
https://doi.org/10.1016/j.micpath.2021.104890
Autor:
Jakub Šebera, Marie Zgarbová, Ondřej Páv, Vladimír Sychrovský, Jiří Fukal, Miloš Buděšínský, Petr Jurečka
Publikováno v:
Journal of Computational Chemistry. 43:132-143
A method for averaging of NMR parameters by molecular dynamics (MD) has been derived from the method of statistical averaging in MD snapshots, benchmarked and applied to structurally dynamic interpretation of the 31 P NMR shift (δ31P ) in DNA phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da180054fb432e67c7855487091c407f
https://doi.org/10.1002/jcc.26778
https://doi.org/10.1002/jcc.26778
Publikováno v:
Acta Crystallogr D Struct Biol
Multicopper oxidases (MCOs) represent a diverse family of enzymes that catalyze the oxidation of either an organic or a metal substrate with concomitant reduction of dioxygen to water. These enzymes contain variable numbers of cupredoxin domains, two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1a30648a9098672b60fa6a77e2698c
https://doi.org/10.1107/s205979832100944x
https://doi.org/10.1107/s205979832100944x
Autor:
Tsukasa Kusakizako, Go Kasuya, Koichi Nakajo, Osamu Nureki, Kan Kobayashi, Tomohiro Nishizawa, Hiroyuki Okamoto, Yoshiaki Kise, Daichi Yamanouchi
Publikováno v:
Nature
Modulation of voltage-gated potassium (Kv) channels by auxiliary subunits is central to the physiological function of channels in the brain and heart1,2. Native Kv4 tetrameric channels form macromolecular ternary complexes with two auxiliary β-subun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153ecc25c73e7be8dde6a9e13c2da6de
https://doi.org/10.1038/s41586-021-03935-z
https://doi.org/10.1038/s41586-021-03935-z
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Dodecamer duplex DNA containing anomeric (α/β‐d) and enantiomeric (β‐l/β‐d) 2’‐deoxycytidine mismatches was studied with respect to base pair stability in the absence and presence of silver ions. Stable duplexes with silver‐mediated c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b11fb87bd3675baf101b9dabbdc42d3
http://europepmc.org/articles/PMC8362019
http://europepmc.org/articles/PMC8362019
Publikováno v:
IUCrJ, Vol 8, Iss 3, Pp 362-371 (2021)
Bacterial toxin–antitoxin (TA) systems correlate strongly with physiological processes in bacteria, such as growth arrest, survival and apoptosis. Here, the first crystal structure of a type II TA complex structure of Klebsiella pneumoniae at 2.3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0004e4fcacab3025357d1e4f5ca58639
http://scripts.iucr.org/cgi-bin/paper?S2052252521000452
http://scripts.iucr.org/cgi-bin/paper?S2052252521000452
Publikováno v:
Nucleic Acids Research
Visualization of double stranded DNA in gels with the binding of the fluorescent dye ethidium bromide has been a basic experimental technique in any molecular biology laboratory for >40 years. The interaction between ethidium and double stranded DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d935645904c4a34bc92afaa519bae44
https://doi.org/10.1093/nar/gkab143
https://doi.org/10.1093/nar/gkab143
Publikováno v:
The Journal of Physical Chemistry B. 125:771-779
Studying the DNA hybridization equilibrium via brute force molecular dynamics (MD) or commonly used advanced sampling approches is notoriously difficult at atomistic lengthscale. However, besides providing a more realistic modeling of this microscopi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe5fc97b91e06cfe3bed3e9362e9d63
https://doi.org/10.1021/acs.jpcb.0c09237
https://doi.org/10.1021/acs.jpcb.0c09237
Autor:
Adam G. Kreutzer, Tuan D. Samdin, Sepehr Haerianardakani, James S. Nowick, Patrick J. Salveson, Gretchen Guaglianone
Publikováno v:
J Am Chem Soc
Oligomers of the β-amyloid peptide, Aβ, play a central role in the pathogenesis and progression of Alzheimer’s disease. Trimers and higher-order oligomers composed of trimers are thought to be the most neurotoxic Aβ oligomers. To gain insights i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b27863ebe8c599c164692b9824c474
https://doi.org/10.1021/jacs.0c09281
https://doi.org/10.1021/jacs.0c09281