Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity

Autor: Sutherland, J.S., Loxton, A.G., Haks, M.C., Kassa, D., Ambrose, L., Lee, J.-S., Ran, L., van Baarle, D., Maertzdorf, J., Howe, R., Mayanja-Kizza, H., Boom, W.H., Thiel, B.A., Crampin, A.C., Hanekom, W., Ota, M.O.C., Dockrell, H., Walzl, G., Kaufmann, S.H.E., Ottenhoff, T.H.M.

Publikováno v: In Clinical Microbiology and Infection April 2014 20(4):O230-O238

Field evaluation of a point-of-care triage test for active tuberculosis (TriageTB).

Autor: Richardson TR; Stellenbosch University, Cape Town, South Africa. cummins@sun.ac.za., Smith B; Stellenbosch University, Cape Town, South Africa., Malherbe ST; Stellenbosch University, Cape Town, South Africa., Shaw JA; Stellenbosch University, Cape Town, South Africa., Noor F; Stellenbosch University, Cape Town, South Africa., MacDonald C; Stellenbosch University, Cape Town, South Africa., van der Spuy GD; Stellenbosch University, Cape Town, South Africa., Stanley K; Stellenbosch University, Cape Town, South Africa., Carstens A; Stellenbosch University, Cape Town, South Africa., Fisher TL; Stellenbosch University, Cape Town, South Africa., van Rensburg I; Stellenbosch University, Cape Town, South Africa., Flinn M; Stellenbosch University, Cape Town, South Africa., Snyders C; Stellenbosch University, Cape Town, South Africa., Johnson I; Stellenbosch University, Cape Town, South Africa., Fransman B; Stellenbosch University, Cape Town, South Africa., Dockrell H; London School of Hygiene and Tropical Medicine, London, UK., Thwaites G; University of Oxford, Oxford, UK., Thuong NTT; University of Oxford, Oxford, UK., Schacht C; LINQ Management, Berlin, Germany., Mayanja-Kizza H; Makerere University, Kampala, Uganda., Nsereko M; Makerere University, Kampala, Uganda., Tjon Kon Fat EM; Leiden University Medical Centre, Leiden, The Netherlands., Corstjens PLAM; Leiden University Medical Centre, Leiden, The Netherlands., Geluk A; Leiden University Medical Centre, Leiden, The Netherlands., Ruhwald M; Foundation for Innovative New Diagnostics, Geneva, Switzerland., Penn-Nicholson A; Foundation for Innovative New Diagnostics, Geneva, Switzerland., Chegou NN; Stellenbosch University, Cape Town, South Africa., Sutherland J; London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Walzl G; Stellenbosch University, Cape Town, South Africa.

Publikováno v: BMC infectious diseases [BMC Infect Dis] 2023 Jul 03; Vol. 23 (1), pp. 447. Date of Electronic Publication: 2023 Jul 03.

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

Autor: Penn-Nicholson, A, Mbandi, SK, Thompson, E, Mendelsohn, SC, Suliman, S, Chegou, NN, Malherbe, ST, Darboe, F, Erasmus, M, Hanekom, WA, Bilek, N, Fisher, M, Kaufmann, SHE, Winter, J, Murphy, M, Wood, R, Morrow, C, Van Rhijn, I, Moody, B, Murray, M, Andrade, BB, Sterling, TR, Sutherland, J, Naidoo, K, Padayatchi, N, Walzl, G, Hatherill, M, Zak, D, Scriba, TJ, Kafaar, F, Workman, L, Mulenga, H, Hughes, EJ, Xasa, O, Veldsman, A, Cloete, Y, Abrahams, D, Moyo, S, Gelderbloem, S, Tameris, M, Geldenhuys, H, Ehrlich, R, Verver, S, Geiter, L, Black, GF, van der Spuy, G, Stanley, K, Kriel, M, Du Plessis, N, Nene, N, Roberts, T, Kleynhans, L, Gutschmidt, A, Smith, B, Loxton, AG, Tromp, G, Tabb, D, Ottenhoff, THM, Klein, MR, Haks, MC, Franken, KLMC, Geluk, A, van Meijgaarden, KE, Joosten, SA, Boom, WH, Thiel, B, Mayanja-Kizza, H, Joloba, M, Zalwango, S, Nsereko, M, Okwera, B, Kisingo, H, Parida, SK, Golinski, R, Maertzdorf, J, Weiner, J, Jacobson, M, Dockrell, H, Smith, S, Gorak-Stolinska, P, Hur, YG, Lalor, M, Lee, JS, Crampin, AC, French, N, Ngwira, B, Ben-Smith, A, Watkins, K, Ambrose, L, Simukonda, F, Mvula, H, Chilongo, F, Saul, J, Branson, K, Mahomed, H, Downing, K

Publikováno v: Scientific reports
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, 10(1):8629. Nature Publishing Group
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Scientific Reports, 10(1). NATURE PUBLISHING GROUP
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports, 10(1):8629. Nature Publishing Group

Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature, RISK6, for multiple applications: identifying individuals at risk of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72b4b335a138b78e75f4f968504b069
https://researchonline.lshtm.ac.uk/id/eprint/4656993/1/s41598-020-65043-8.pdf

BCG Specific and Nonspecific Effects: Different Questions, Similar Challenges.

Autor: Prentice, Sarah, Dockrell, Hazel M, Prentice, S, Dockrell, H M

Publikováno v: Journal of Infectious Diseases; Oct2021, Vol. 224 Issue 7, p1105-1108, 4p

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