Zobrazeno 1 - 10
of 30 831
pro vyhledávání: '"Docking (molecular)"'
Autor:
Truc Ly Nguyen, Heebal Kim
Publikováno v:
Infectious Disease Modelling, Vol 9, Iss 3, Pp 763-774 (2024)
Respiratory syncytial virus (RSV) poses a significant global health threat, especially affecting infants and the elderly. Addressing this, the present study proposes an innovative approach to vaccine design, utilizing immunoinformatics and computatio
Externí odkaz:
https://doaj.org/article/2a273453400148c69752ce2d3174db1a
Autor:
Truc Ly Nguyen, Heebal Kim
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 3, Pp 391-405 (2024)
Mycobacterium tuberculosis (MTB) is the causative agent of tuberculosis (TB), a prevalent airborne infectious disease. Despite the availability of the Bacille Calmette-Guerin vaccine, its global efficacy remains modest, and tuberculosis persists as a
Externí odkaz:
https://doaj.org/article/7ccde9e93ffc4fe58d0ebc125c50b8e4
Autor:
Areeba Akram, Azra Sakhawat, Muhammad Usman Ghani, Muhammad Umer Khan, Raima Rehman, Qurban Ali, Peng Jin-liang, Daoud Ali
Publikováno v:
AMB Express, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Cystic Fibrosis Transmembrane Regulator (CFTR) is a significant protein that is responsible for the movement of ions across cell membranes. The cystic fibrosis (CF) occur due to the mutations in the CFTR gene as it produces the dysfunctional
Externí odkaz:
https://doaj.org/article/3e115058162e4d33b1715c471ef6b5f6
Autor:
Françueuda Alves da Silva, Eliane Alves Lustosa, Gislaine da Silva Rodrigues, Abrahão Alves de Oliveira Filho, Cássio Ilan Soares Medeiros
Publikováno v:
Revista Principia, Vol 61, Iss 3, Pp 811-825 (2024)
As infecções bacterianas e a resistência antimicrobiana, particularmente de Klebsiella pneumoniae, continuam sendo algumas das questões mais desafiadoras que ameaçam a saúde das pessoas em todo o mundo. Compostos naturais derivados de plantas t
Externí odkaz:
https://doaj.org/article/cfba2edbe7ca411aa2b5e1abef819fa9
Autor:
Shila Kumari Singh, Minakshi Bhattacharjee, Balagopalan Unni, Rajpal Singh Kashyap, Abdul Malik, Suhail Akhtar, Sabiha Fatima
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionStaphylococcus aureus is a highly resistant pathogen. It has multiple virulence factors, which makes it one of the most pathogenic bacteria for humankind. The vast increase in antibiotic resistance in these bacteria is a warning of existi
Externí odkaz:
https://doaj.org/article/a57bcba6b5ac45b8ab70c5758ffaa50c
Autor:
Mona A.M. Hussein, Mayasar I. Al-zaban, Yahia A.G. Mahmoud, Amin A. Al-Doaiss, Safia M.A. Bahshwan, Khalid A. El-Dougdoug, Mohamed R. EL-Shanshory
Publikováno v:
Saudi Journal of Biological Sciences, Vol 31, Iss 8, Pp 104031- (2024)
Human Rotavirus (HRV) is the causative pathogen of severe acute enteric infections that cause mortality among children worldwide. This study focuses on developing a new and effective treatment for rotavirus infection using an extract from Saccharomyc
Externí odkaz:
https://doaj.org/article/6e95e809193a4987a51b181e55f9ae18
Publikováno v:
Communicative & Integrative Biology, Vol 17, Iss 1 (2024)
ABSTRACTAlzheimer’s disease (AD) is a common brain disease associated with cognitive impairment and dementia. donepezil, an acetylcholinesterase (AChE) inhibitor drug as a commercial AD drug represents a non-cost-effective treatment with the toxic
Externí odkaz:
https://doaj.org/article/816d6af4b58e4b1d8dd720678dcdf54d
Autor:
Zakariae Abbaoui, Mohammed Merzouki, Imane Oualdi, Abdelhamid Bitari, Abdelouhed Oussaid, Allal Challioui, Rachid Touzani, Belkheir Hammouti, Wilson Agerico Diño
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100159- (2024)
The global surge in Alzheimer's disease poses a significant public health concern. In response, we study the efficacy of carnosic acid and related abietane-type diterpenes extracted from rosemary as acetylcholinesterase (AChE) inhibitors. Our analyse
Externí odkaz:
https://doaj.org/article/b407782a9cd444dbae678087a26fb51d
Autor:
Johan Alexander Villada Ramos, Johanny Aguillón Osma, Beatriz Restrepo Cortes, Nelsy Loango Chamarro, María Elena Maldonado Celis
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101453- (2023)
Plant bioactive compounds such as flavonoids and triterpenes can affect lipid metabolism. Here, we report the cytotoxic and lipid-lowering activities of the ethanolic extract of P. edulis leaves on human colon adenocarcinoma SW480 cells, also the mol
Externí odkaz:
https://doaj.org/article/1ab445f7f64946f9b3bf79de3437cded
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