Zobrazeno 1 - 10
of 480
pro vyhledávání: '"Docetaxel-resistance"'
Autor:
Bisheng Cheng, Lingfeng Li, Tianlong Luo, Qiong Wang, Yong Luo, Shoumin Bai, Kaiwen Li, Yiming Lai, Hai Huang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Docetaxel resistance represents a significant obstacle in the treatment of prostate cancer. The intricate interplay between cytokine signalling pathways and transcriptional control mechanisms in cancer cells contributes to chemoth
Externí odkaz:
https://doaj.org/article/6c2da2d5747e43dc8b5dce5dfbf4a757
Autor:
Yuhao Zhou, Fei Li, Bangyu Zou, Xiaofeng Zhou, Lianmin Luo, Sicheng Dong, Zhiqing He, Zhixiong Zhang, Liqiong Liao, Hongxing Liu, Chao Cai, Di Gu, Xiaolu Duan
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Purpose To investigate the influence of β-arrestin2 on the docetaxel resistance in castration-resistant prostate cancer (CRPC) and elucidate the underlying molecular mechanisms. Methods PC3 and DU145 cells with stable β-arrestin2 overexpre
Externí odkaz:
https://doaj.org/article/01069a0d2c2b407ba4c607822e9381c5
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 9, Pp 873-882 (2023)
Abstract This study was to explore the regulatory effect of long non‐coding RNA LINC01559 on Docetaxel resistance in breast carcinoma (BCa) and its underlying mechanism. In the present study, we found that LINC01559 expression was elevated and LINC
Externí odkaz:
https://doaj.org/article/7761cf3144664691a255686171a1ace3
Autor:
Qing Liu, Hangsheng Zhou, Yanjuan Wang, Jiandong Gui, Dongjie Yang, Jian Sun, Dongsheng Ge, Sheng Wu, Qin Liu, Lijie Zhu, Yuanyuan Mi
Publikováno v:
Translational Oncology, Vol 40, Iss , Pp 101830- (2024)
Castration-resistant prostate cancer (CRPC) is a fatal disease that evolves from prostate cancer due to drug resistance after long-term androgen deprivation therapy. In this study, we aimed to find novel molecular targets for treating CRPC. Through p
Externí odkaz:
https://doaj.org/article/8219769e6af64367a723ce2c0f62796a
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background To investigate underlying mechanism of JMJD2A in regulating cytoskeleton remodeling in castration-resistant prostate cancer (CRPC) resistant to docetaxel. Methods Tissue samples from CRPC patients were collected, and the expressio
Externí odkaz:
https://doaj.org/article/710b7b2d863041e6996a9cabbe6713cd
Autor:
Yang Yang, Haixiang Qin, Meng Ding, Changwei Ji, Wei Chen, Wenli Diao, Haoli Yin, Mengxia Chen, Weidong Gan, Hongqian Guo
Publikováno v:
FEBS Open Bio, Vol 13, Iss 2, Pp 257-269 (2023)
Docetaxel (DTX) plays an important role in treating advanced prostate cancer (PCa). However, nearly all patients receiving DTX therapy ultimately progress to DTX resistance. How to address DTX resistance in PCa remains a key challenge for all urologi
Externí odkaz:
https://doaj.org/article/2bf743effc7d4531a4036adbd1e706b9
Akademický článek
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Autor:
Min Jiang, Feng Qi, Kai Zhang, Xiaofei Zhang, Jingjing Ma, Suhua Xia, Longbang Chen, Zhengyuan Yu, Jing Chen, Dongqin Chen
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background Long non-coding RNAs (lncRNAs) are implicated in the development of multiple cancers. In our previous study, we demonstrated that HDAC1/4-mediated silencing of microRNA-200b (miR-200b) enhances docetaxel (DTX)-resistance of human
Externí odkaz:
https://doaj.org/article/f4c0f938d069486081dc1af8147ed008
Autor:
Haoli Yin, Haixiang Qin, Lei Yang, Mengxia Chen, Yang Yang, Wenlong Zhang, Jiange Hao, Qun Lu, Jingyan Shi, Junlong Zhuang, Xuefeng Qiu, Hongqian Guo
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background Docetaxel (DTX) is the most widely prescribed first-line chemotherapy for advanced prostate cancer (PCa). Unfortunately, DTX resistance invariably emerges, leading to worse prognosis of PCa. Growing evidence has shown that circRNA
Externí odkaz:
https://doaj.org/article/fe1163d863574fb69ab8ffa5eca94787
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Acquisition of the chemoresistance to docetaxel (DTX), a microtubule-targeting agent, has been a huge obstacle in treatment for metastatic castration-resistant prostate cancer (mCRPC). Recently, strategies targeting the mitosis er
Externí odkaz:
https://doaj.org/article/b1aac69f139047fb874c4591fe1ca100