Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Autor: Evans, RA, Leavy, OC, Richardson, M, Elneima, O, McCauley, HJC, Shikotra, A, Singapuri, A, Sereno, M, Saunders, RM, Harris, VC, Houchen-Wolloff, L, Aul, R, Beirne, P, Bolton, CE, Brown, JS, Choudhury, G, Diar-Bakerly, N, Easom, N, Echevarria, C, Fuld, J, Hart, N, Hurst, J, Jones, MG, Parekh, D, Pfeffer, P, Rahman, NM, Rowland-Jones, SL, Shah, AM, Wootton, DG, Chalder, T, Davies, MJ, De Soyza, A, Geddes, JR, Greenhalf, W, Greening, NJ, Heaney, LG, Heller, S, Howard, LS, Jacob, J, Jenkins, RG, Lord, JM, Man, WD-C, McCann, GP, Neubauer, S, Openshaw, PJM, Porter, JC, Rowland, MJ, Scott, JT, Semple, MG, Singh, SJ, Thomas, DC, Toshner, M, Lewis, KE, Thwaites, RS, Briggs, A, Docherty, AB, Kerr, S, Lone, NI, Quint, J, Sheikh, A, Thorpe, M, Zheng, B, Chalmers, JD, Ho, LP, Horsley, A, Marks, M, Poinasamy, K, Raman, B, Harrison, EM, Wain, LV, Brightling, CE, Abel, K, Adamali, H, Adeloye, D, Adeyemi, O, Adrego, R, Jimenez, LAA, Ahmad, S, Haider, NA, Ahmed, R, Ahwireng, N, Ainsworth, M, Al-Sheklly, B, Alamoudi, A, Ali, M, Aljaroof, M, All, AM, Allan, L, Allen, RJ, Allerton, L, Allsop, L, Almeida, P, Altmann, D, Corral, MA, Amoils, S, Anderson, D, Antoniades, C, Arbane, G, Arias, A, Armour, C, Armstrong, L, Armstrong, N, Arnold, D, Arnold, H, Ashish, A, Ashworth, A, Ashworth, M, Aslani, S, Assefa-Kebede, H, Atkin, C, Atkin, P, Aung, H, Austin, L, Avram, C, Ayoub, A, Babores, M, Baggott, R, Bagshaw, J, Baguley, D, Bailey, L, Baillie, JK, Bain, S, Bakali, M, Bakau, M, Baldry, E, Baldwin, D, Ballard, C, Banerjee, A, Bang, B, Barker, RE, Barman, L, Barratt, S, Barrett, F, Basire, D, Basu, N, Bates, M, Bates, A, Batterham, R, Baxendale, H, Bayes, H, Beadsworth, M, Beckett, P, Beggs, M, Begum, M, Bell, D, Bell, R, Bennett, K, Beranova, E, Bermperi, A, Berridge, A, Berry, C, Betts, S, Bevan, E, Bhui, K, Bingham, M, Birchall, K, Bishop, L, Bisnauthsing, K, Blaikely, J, Bloss, A, Bolger, A, Bonnington, J, Botkai, A, Bourne, C, Bourne, M, Bramham, K, Brear, L, Breen, G, Breeze, J, Bright, E, Brill, S, Brindle, K, Broad, L, Broadley, A, Brookes, C, Broome, M, Brown, A, Brown, J, Brown, M, Brown, V, Brown, CW, Brugha, T, Brunskill, N, Buch, M, Buckley, P, Bularga, A, Bullmore, E, Burden, L, Burdett, T, Burn, D, Burns, G, Burns, A, Busby, J, Butcher, R, Butt, A, Byrne, S, Cairns, P, Calder, PC, Calvelo, E, Carborn, H, Card, B, Carr, C, Carr, L, Carson, G, Carter, P, Casey, A, Cassar, M, Cavanagh, J, Chablani, M, Chambers, RC, Chan, F, Channon, KM, Chapman, K, Charalambou, A, Chaudhuri, N, Checkley, A, Chen, J, Cheng, Y, Chetham, L, Childs, C, Chilvers, ER, Chinoy, H, Chiribiri, A, Chong-James, K, Choudhury, N, Chowienczyk, P, Christie, C, Chrystal, M, Clark, D, Clark, C, Clarke, J, Clohisey, S, Coakley, G, Coburn, Z, Coetzee, S, Cole, J, Coleman, C, Conneh, F, Connell, D, Connolly, B, Connor, L, Cook, A, Cooper, B, Cooper, J, Cooper, S, Copeland, D, Cosier, T, Coulding, M, Coupland, C, Cox, E, Craig, T, Crisp, P, Cristiano, D, Crooks, MG, Cross, A, Cruz, I, Cullinan, P, Cuthbertson, D, Daines, L, Dalton, M, Daly, P, Daniels, A, Dark, P, Dasgin, J, David, A, David, C, Davies, E, Davies, F, Davies, G, Davies, GA, Davies, K, Dawson, J, Daynes, E, Deakin, B, Deans, A, Deas, C, Deery, J, Defres, S, Dell, A, Dempsey, K, Denneny, E, Dennis, J, Dewar, A, Dharmagunawardena, R, Dickens, C, Dipper, A, Diver, S, Diwanji, SN, Dixon, M, Djukanovic, R, Dobson, H, Dobson, SL, Donaldson, A, Dong, T, Dormand, N, Dougherty, A, Dowling, R, Drain, S, Draxlbauer, K, Drury, K, Dulawan, P, Dunleavy, A, Dunn, S, Earley, J, Edwards, S, Edwardson, C, El-Taweel, H, Elliott, A, Elliott, K, Ellis, Y, Elmer, A, Evans, D, Evans, H, Evans, J, Evans, R, Evans, RI, Evans, T, Evenden, C, Evison, L, Fabbri, L, Fairbairn, S, Fairman, A, Fallon, K, Faluyi, D, Favager, C, Fayzan, T, Featherstone, J, Felton, T, Finch, J, Finney, S, Finnigan, J, Finnigan, L, Fisher, H, Fletcher, S, Flockton, R, Flynn, M, Foot, H, Foote, D, Ford, A, Forton, D, Fraile, E, Francis, C, Francis, R, Francis, S, Frankel, A, Fraser, E, Free, R, French, N, Fu, X, Furniss, J, Garner, L, Gautam, N, George, J, George, P, Gibbons, M, Gill, M, Gilmour, L, Gleeson, F, Glossop, J, Glover, S, Goodman, N, Goodwin, C, Gooptu, B, Gordon, H, Gorsuch, T, Greatorex, M, Greenhaff, PL, Greenhalgh, A, Greenwood, J, Gregory, H, Gregory, R, Grieve, D, Griffin, D, Griffiths, L, Guerdette, A-M, Guio, BG, Gummadi, M, Gupta, A, Gurram, S, Guthrie, E, Guy, Z, Henson, HH, Hadley, K, Haggar, A, Hainey, K, Hairsine, B, Haldar, P, Hall, I, Hall, L, Halling-Brown, M, Hamil, R, Hancock, A, Hancock, K, Hanley, NA, Haq, S, Hardwick, HE, Hardy, E, Hardy, T, Hargadon, B, Harrington, K, Harris, E, Harrison, P, Harvey, A, Harvey, M, Harvie, M, Haslam, L, Havinden-Williams, M, Hawkes, J, Hawkings, N, Haworth, J, Hayday, A, Haynes, M, Hazeldine, J, Hazelton, T, Heeley, C, Heeney, JL, Heightman, M, Henderson, M, Hesselden, L, Hewitt, M, Highett, V, Hillman, T, Hiwot, T, Hoare, A, Hoare, M, Hockridge, J, Hogarth, P, Holbourn, A, Holden, S, Holdsworth, L, Holgate, D, Holland, M, Holloway, L, Holmes, K, Holmes, M, Holroyd-Hind, B, Holt, L, Hormis, A, Hosseini, A, Hotopf, M, Howard, K, Howell, A, Hufton, E, Hughes, AD, Hughes, J, Hughes, R, Humphries, A, Huneke, N, Hurditch, E, Husain, M, Hussell, T, Hutchinson, J, Ibrahim, W, Ilyas, F, Ingham, J, Ingram, L, Ionita, D, Isaacs, K, Ismail, K, Jackson, T, James, WY, Jarman, C, Jarrold, I, Jarvis, H, Jastrub, R, Jayaraman, B, Jezzard, P, Jiwa, K, Johnson, C, Johnson, S, Johnston, D, Jolley, CJ, Jones, D, Jones, G, Jones, H, Jones, I, Jones, L, Jones, S, Jose, S, Kabir, T, Kaltsakas, G, Kamwa, V, Kanellakis, N, Kaprowska, S, Kausar, Z, Keenan, N, Kelly, S, Kemp, G, Kerslake, H, Key, AL, Khan, F, Khunti, K, Kilroy, S, King, B, King, C, Kingham, L, Kirk, J, Kitterick, P, Klenerman, P, Knibbs, L, Knight, S, Knighton, A, Kon, O, Kon, S, Kon, SS, Koprowska, S, Korszun, A, Koychev, I, Kurasz, C, Kurupati, P, Laing, C, Lamlum, H, Landers, G, Langenberg, C, Lasserson, D, Lavelle-Langham, L, Lawrie, A, Lawson, C, Layton, A, Lea, A, Lee, D, Lee, J-H, Lee, E, Leitch, K, Lenagh, R, Lewis, D, Lewis, J, Lewis, V, Lewis-Burke, N, Li, X, Light, T, Lightstone, L, Lilaonitkul, W, Lim, L, Linford, S, Lingford-Hughes, A, Lipman, M, Liyanage, K, Lloyd, A, Logan, S, Lomas, D, Loosley, R, Lota, H, Lovegrove, W, Lucey, A, Lukaschuk, E, Lye, A, Lynch, C, MacDonald, S, MacGowan, G, Macharia, I, Mackie, J, Macliver, L, Madathil, S, Madzamba, G, Magee, N, Magtoto, MM, Mairs, N, Majeed, N, Major, E, Malein, F, Malim, M, Mallison, G, Mandal, S, Mangion, K, Manisty, C, Manley, R, March, K, Marciniak, S, Marino, P, Mariveles, M, Marouzet, E, Marsh, S, Marshall, B, Marshall, M, Martin, J, Martineau, A, Martinez, LM, Maskell, N, Matila, D, Matimba-Mupaya, W, Matthews, L, Mbuyisa, A, McAdoo, S, McCall, JW, McAllister-Williams, H, McArdle, A, McArdle, P, McAulay, D, McCormick, J, McCormick, W, McCourt, P, McGarvey, L, McGee, C, Mcgee, K, McGinness, J, McGlynn, K, McGovern, A, McGuinness, H, McInnes, IB, McIntosh, J, McIvor, E, McIvor, K, McLeavey, L, McMahon, A, McMahon, MJ, McMorrow, L, Mcnally, T, McNarry, M, McNeill, J, McQueen, A, McShane, H, Mears, C, Megson, C, Megson, S, Mehta, P, Meiring, J, Melling, L, Mencias, M, Menzies, D, Morillas, MM, Michael, A, Milligan, L, Miller, C, Mills, C, Mills, NL, Milner, L, Misra, S, Mitchell, J, Mohamed, A, Mohamed, N, Mohammed, S, Molyneaux, PL, Monteiro, W, Moriera, S, Morley, A, Morrison, L, Morriss, R, Morrow, A, Moss, AJ, Moss, P, Motohashi, K, Msimanga, N, Mukaetova-Ladinska, E, Munawar, U, Murira, J, Nanda, U, Nassa, H, Nasseri, M, Neal, A, Needham, R, Neill, P, Newell, H, Newman, T, Newton-Cox, A, Nicholson, T, Nicoll, D, Nolan, CM, Noonan, MJ, Norman, C, Novotny, P, Nunag, J, Nwafor, L, Nwanguma, U, Nyaboko, J, O'Donnell, K, O'Brien, C, O'Brien, L, O'Regan, D, Odell, N, Ogg, G, Olaosebikan, O, Oliver, C, Omar, Z, Orriss-Dib, L, Osborne, L, Osbourne, R, Ostermann, M, Overton, C, Owen, J, Oxton, J, Pack, J, Pacpaco, E, Paddick, S, Painter, S, Pakzad, A, Palmer, S, Papineni, P, Paques, K, Paradowski, K, Pareek, M, Parfrey, H, Pariante, C, Parker, S, Parkes, M, Parmar, J, Patale, S, Patel, B, Patel, M, Patel, S, Pattenadk, D, Pavlides, M, Payne, S, Pearce, L, Pearl, JE, Peckham, D, Pendlebury, J, Peng, Y, Pennington, C, Peralta, I, Perkins, E, Peterkin, Z, Peto, T, Petousi, N, Petrie, J, Phipps, J, Pimm, J, Hanley, KP, Pius, R, Plant, H, Plein, S, Plekhanova, T, Plowright, M, Polgar, O, Poll, L, Porter, J, Portukhay, S, Powell, N, Prabhu, A, Pratt, J, Price, A, Price, C, Price, D, Price, L, Prickett, A, Propescu, J, Pugmire, S, Quaid, S, Quigley, J, Qureshi, H, Qureshi, IN, Radhakrishnan, K, Ralser, M, Ramos, A, Ramos, H, Rangeley, J, Rangelov, B, Ratcliffe, L, Ravencroft, P, Reddington, A, Reddy, R, Redfearn, H, Redwood, D, Reed, A, Rees, M, Rees, T, Regan, K, Reynolds, W, Ribeiro, C, Richards, A, Richardson, E, Rivera-Ortega, P, Roberts, K, Robertson, E, Robinson, E, Robinson, L, Roche, L, Roddis, C, Rodger, J, Ross, A, Ross, G, Rossdale, J, Rostron, A, Rowe, A, Rowland, A, Rowland, J, Roy, K, Roy, M, Rudan, I, Russell, R, Russell, E, Saalmink, G, Sabit, R, Sage, EK, Samakomva, T, Samani, N, Sampson, C, Samuel, K, Samuel, R, Sanderson, A, Sapey, E, Saralaya, D, Sargant, J, Sarginson, C, Sass, T, Sattar, N, Saunders, K, Saunders, P, Saunders, LC, Savill, H, Saxon, W, Sayer, A, Schronce, J, Schwaeble, W, Scott, K, Selby, N, Sewell, TA, Shah, K, Shah, P, Shankar-Hari, M, Sharma, M, Sharpe, C, Sharpe, M, Shashaa, S, Shaw, A, Shaw, K, Shaw, V, Shelton, S, Shenton, L, Shevket, K, Short, J, Siddique, S, Siddiqui, S, Sidebottom, J, Sigfrid, L, Simons, G, Simpson, J, Simpson, N, Singh, C, Singh, S, Sissons, D, Skeemer, J, Slack, K, Smith, A, Smith, D, Smith, S, Smith, J, Smith, L, Soares, M, Solano, TS, Solly, R, Solstice, AR, Soulsby, T, Southern, D, Sowter, D, Spears, M, Spencer, LG, Speranza, F, Stadon, L, Stanel, S, Steele, N, Steiner, M, Stensel, D, Stephens, G, Stephenson, L, Stern, M, Stewart, I, Stimpson, R, Stockdale, S, Stockley, J, Stoker, W, Stone, R, Storrar, W, Storrie, A, Storton, K, Stringer, E, Strong-Sheldrake, S, Stroud, N, Subbe, C, Sudlow, CL, Suleiman, Z, Summers, C, Summersgill, C, Sutherland, D, Sykes, DL, Sykes, R, Talbot, N, Tan, AL, Tarusan, L, Tavoukjian, V, Taylor, A, Taylor, C, Taylor, J, Te, A, Tedd, H, Tee, CJ, Teixeira, J, Tench, H, Terry, S, Thackray-Nocera, S, Thaivalappil, F, Thamu, B, Thickett, D, Thomas, C, Thomas, S, Thomas, AK, Thomas-Woods, T, Thompson, T, Thompson, AAR, Thornton, T, Tilley, J, Tinker, N, Tiongson, GF, Tobin, M, Tomlinson, J, Tong, C, Touyz, R, Tripp, KA, Tunnicliffe, E, Turnbull, A, Turner, E, Turner, S, Turner, V, Turner, K, Turney, S, Turtle, L, Turton, H, Ugoji, J, Ugwuoke, R, Upthegrove, R, Valabhji, J, Ventura, M, Vere, J, Vickers, C, Vinson, B, Wade, E, Wade, P, Wainwright, T, Wajero, LO, Walder, S, Walker, S, Wall, E, Wallis, T, Walmsley, S, Walsh, JA, Walsh, S, Warburton, L, Ward, TJC, Warwick, K, Wassall, H, Waterson, S, Watson, E, Watson, L, Watson, J, Welch, C, Welch, H, Welsh, B, Wessely, S, West, S, Weston, H, Wheeler, H, White, S, Whitehead, V, Whitney, J, Whittaker, S, Whittam, B, Whitworth, V, Wight, A, Wild, J, Wilkins, M, Wilkinson, D, Williams, N, Williams, J, Williams-Howard, SA, Willicombe, M, Willis, G, Willoughby, J, Wilson, A, Wilson, D, Wilson, I, Window, N, Witham, M, Wolf-Roberts, R, Wood, C, Woodhead, F, Woods, J, Wormleighton, J, Worsley, J, Wraith, D, Wright, C, Wright, L, Wright, S, Wyles, J, Wynter, I, Xu, M, Yasmin, N, Yasmin, S, Yates, T, Yip, KP, Young, B, Young, S, Young, A, Yousuf, AJ, Zawia, A, Zeidan, L, Zhao, B, Zongo, O

Publikováno v: The PHOSP-COVID Collaborative Group, Evans, R A, Richardson, M, Brown, J S, Hart, N, Jones, M G, Rahman, N M, Shah, A M, Davies, M J, Geddes, J R, Heaney, L G, Jenkins, R G, McCann, G P, Porter, J C, Rowland, M J, Scott, J T, Semple, M G, Singh, S J, Kerr, S, Ahmad, S, Ali, M, Armour, C, Baillie, J K, Banerjee, A, Barker, R E, Begum, M, Bell, D, Bell, R, Bennett, K, Bingham, M, Bourne, M, Brown, A, Brown, J S, Brown, M, Brown, V, Burns, G, Burns, A, Busby, J, Butt, A, Byrne, S, Cairns, P, Carr, C, Carson, G, Casey, A, Chambers, R C, Chapman, K, Chen, J, Cheng, Y, Clarke, J, Cole, J, Connolly, B, Cooper, B, Cooper, J, Cooper, S, Craig, T, Cross, A, Daly, P, Davies, G, Davies, G, Dobson, S L, Drain, S, Edwards, S, Elliott, A, Elliott, K, Evans, D, Evans, J, Evans, R A, Evans, R A, Fletcher, S, Flynn, M, Ford, A, Francis, S, Fu, X, George, J, Glover, S, Goodwin, C, Greenwood, J, Grieve, D, Griffin, D, Gupta, A, Hall, L, Hanley, N A, Harrington, K, Harris, E, Harvey, A, Harvey, M, Hewitt, M, Holloway, L, Howard, K, Hughes, A D, Hughes, J, Hughes, R, Hutchinson, J, Johnson, C, Johnson, S, Johnston, D, Jones, D, Jones, H, Jones, L, Jones, S, Kelly, S, Khan, F, Kilroy, S, King, B, Kirk, J, Lee, J H, Lewis, J, Li, X, Lynch, C, Magee, N, Marshall, B, Marshall, M, Martin, J, Matthews, L, McArdle, A, McCormick, J, McCormick, W, McCourt, P, McGarvey, L, McInnes, I B, McIntosh, J, McIvor, K, McMahon, A, McMahon, M J, Mcnally, T, McNeill, J, Miller, C, Mills, C, Milner, L, Mitchell, J, Mohamed, A, Mohammed, S, Morrison, L, Newman, T, Nolan, C M, O'Donnell, K, O'Brien, C, O'Brien, L, Owen, J, Palmer, S, Pavlides, M, Peng, Y, Peto, T, Porter, J C, Powell, N, Pratt, J, Price, A, Price, D, Price, L, Reed, A, Robertson, E, Robinson, E, Robinson, L, Ross, A, Ross, G, Roy, M, Russell, E, Scott, K, Sewell, T A, Sharma, M, Shaw, A, Siddiqui, S, Simpson, J, Simpson, N, Singh, S J, Smith, A, Smith, D, Smith, S, Smith, J, Smith, L, Stewart, I, Taylor, A, Taylor, C, Taylor, J, Thomas, C, Thomas, S, Thompson, T, Thompson, A A R, Turner, S, Walker, S, Walsh, J A, Walsh, S, Ward, T J C, Watson, E, Watson, L, Watson, J, White, S, Wilkinson, D, Williams, J, Wilson, A, Wilson, D, Wilson, I, Woods, J, Wright, C, Wright, L, Wright, S, Xu, M, Young, S & Young, A 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study ', The Lancet Respiratory Medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Group, PHOSP-COVID C & Dark, P 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. ', The Lancet. Respiratory medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/s2213-2600(22)00127-8
Chalder, T 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK : a prospective observational study ', The lancet. Respiratory medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Docherty, A B, Kerr, S, Lone, N I, Sheikh, A, Zheng, B & Harrison, E M & Baillie, J K 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK : a prospective observational study ', The Lancet Respiratory Medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8

Background No effective pharmacological or non-pharmacological interventions exist for patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for COVID-19, identify factors associated with patient-perceived recovery,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f0a5a60fd58251c9e3d96642f84553
https://doi.org/10.1016/s2213-2600(22)00127-8

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study.

Autor: Neale I; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; NDM Centre For Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit , Bangkok, Thailand., Ali M; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; NDM Centre For Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit , Bangkok, Thailand., Kronsteiner B; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; NDM Centre For Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom., Longet S; Nuffield Department of Medicine, Pandemic Sciences Institute, University of Oxford , Oxford, United Kingdom.; Nuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford , Oxford, United Kingdom., Abraham P; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; NDM Centre For Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom., Deeks AS; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; Oxford University Hospitals NHS Foundation Trust , Oxford, United Kingdom., Brown A; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom., Moore SC; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, United Kingdom., Stafford L; Nuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford , Oxford, United Kingdom., Dobson SL; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, United Kingdom., Plowright M; Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield , Sheffield, United Kingdom., Newman TAH; Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield , Sheffield, United Kingdom., Wu MY; Covid Surveillance Unit, The Francis Crick Institute , London, United Kingdom., Carr EJ; The Francis Crick Institute , London, United Kingdom., Beale R; The Francis Crick Institute , London, United Kingdom.; UCL Department of Renal Medicine, Royal Free Hospital , London, United Kingdom., Otter AD; UK Health Security Agency , Porton Down, United Kingdom., Hopkins S; UK Health Security Agency , London, United Kingdom., Hall V; UK Health Security Agency , London, United Kingdom., Tomic A; National Emerging Infectious Diseases Laboratories, Boston University , Boston, Massachusetts, USA.; Department of Microbiology, Boston University School of Medicine , Boston, Massachusetts, USA.; Department of Biomedical Engineering, Boston University , Boston, Massachusetts, USA.; Department of Paediatrics, Oxford Vaccine Group, University of Oxford , Oxford, United Kingdom., Payne RP; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University , Newcastle, United Kingdom., Barnes E; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; Oxford University Hospitals NHS Foundation Trust , Oxford, United Kingdom.; Translational Gastroenterology Unit, University of Oxford , Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, University of Oxford , Oxford, United Kingdom., Richter A; Institute of Immunology and Immunotherapy, College of Medical and Dental Science, University of Birmingham , Birmingham, United Kingdom.; University Hospitals Birmingham NHS Foundation Trust , Birmingham, United Kingdom., Duncan CJA; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University , Newcastle, United Kingdom.; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust , Newcastle, United Kingdom., Turtle L; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, United Kingdom.; Liverpool University Hospitals NHS Foundation Trust , Liverpool, United Kingdom., de Silva TI; Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield , Sheffield, United Kingdom., Carroll M; Nuffield Department of Medicine, Pandemic Sciences Institute, University of Oxford , Oxford, United Kingdom.; Nuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford , Oxford, United Kingdom., Lambe T; Department of Paediatrics, Oxford Vaccine Group, University of Oxford , Oxford, United Kingdom.; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford , Oxford, United Kingdom., Klenerman P; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; Oxford University Hospitals NHS Foundation Trust , Oxford, United Kingdom.; Translational Gastroenterology Unit, University of Oxford , Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, University of Oxford , Oxford, United Kingdom., Dunachie S; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; NDM Centre For Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford , Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit , Bangkok, Thailand.; Oxford University Hospitals NHS Foundation Trust , Oxford, United Kingdom.

Publikováno v: MBio [mBio] 2023 Oct 31; Vol. 14 (5), pp. e0121223. Date of Electronic Publication: 2023 Sep 01.

Evolution of long-term vaccine-induced and hybrid immunity in healthcare workers after different COVID-19 vaccine regimens.

Autor: Moore SC; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Kronsteiner B; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Longet S; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Adele S; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Deeks AS; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Liu C; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Dejnirattisai W; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Division of Emerging Infectious Disease, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Reyes LS; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Meardon N; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Faustini S; Institute for Immunology and Immunotherapy, College of Medical and Dental Science, University of Birmingham, Birmingham, UK., Al-Taei S; Institute for Immunology and Immunotherapy, College of Medical and Dental Science, University of Birmingham, Birmingham, UK., Tipton T; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Hering LM; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Angyal A; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Brown R; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Nicols AR; Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Dobson SL; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Supasa P; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tuekprakhon A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Cross A; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Tyerman JK; Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Hornsby H; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Grouneva I; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Plowright M; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Zhang P; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Newman TAH; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Nell JM; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Abraham P; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Ali M; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Malone T; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Neale I; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Phillips E; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Wilson JD; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK; Oxford University Medical School, Medical Sciences Division, University of Oxford, Oxford, UK., Murray SM; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Zewdie M; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Shields A; Institute for Immunology and Immunotherapy, College of Medical and Dental Science, University of Birmingham, Birmingham, UK; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Horner EC; MRC Toxicology Unit, University of Cambridge, Cambridge, UK., Booth LH; MRC Toxicology Unit, University of Cambridge, Cambridge, UK., Stafford L; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bibi S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Wootton DG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Mentzer AJ; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Conlon CP; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jeffery K; Oxford University Hospitals NHS Foundation Trust, Oxford, UK; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Matthews PC; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; The Francis Crick Institute, London, UK; Division of Infection and Immunity, University College London, London, UK; Department of Infectious Diseases, University College London Hospital NHS Foundation Trust, London, UK., Pollard AJ; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Brown A; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Rowland-Jones SL; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Mongkolsapaya J; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Payne RP; Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Lambe T; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Thaventhiran JED; MRC Toxicology Unit, University of Cambridge, Cambridge, UK., Screaton G; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Barnes E; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Hopkins S; UK Health Security Agency, London, UK; Faculty of Medicine, Department of Infectious Disease, Imperial College London, London, UK; NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, University of Oxford, Oxford, UK., Hall V; UK Health Security Agency, London, UK; NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, University of Oxford, Oxford, UK., Duncan CJA; Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, Newcastle, UK; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Richter A; Institute for Immunology and Immunotherapy, College of Medical and Dental Science, University of Birmingham, Birmingham, UK; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Carroll M; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., de Silva TI; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Klenerman P; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; Translational Gastroenterology Unit, University of Oxford, Oxford, UK. Electronic address: paul.klenerman@ndm.ox.ac.uk., Dunachie S; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford Centre for Global Health Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand., Turtle L; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK. Electronic address: lance.turtle@liverpool.ac.uk.

Publikováno v: Med (New York, N.Y.) [Med] 2023 Mar 10; Vol. 4 (3), pp. 191-215.e9. Date of Electronic Publication: 2023 Feb 16.

Reply to: Assessing the efficiency of Verily's automated process for production and release of male Wolbachia-infected mosquitoes.

Autor: Crawford JE; Verily Life Sciences, South San Francisco, CA, USA. jacobcrawford@verily.com., Hopkins KC; Verily Life Sciences, South San Francisco, CA, USA., Buchman A; Verily Life Sciences, South San Francisco, CA, USA., Zha T; Verily Life Sciences, South San Francisco, CA, USA., Howell P; Verily Life Sciences, South San Francisco, CA, USA., Kakani E; Verily Life Sciences, South San Francisco, CA, USA., Ohm JR; Verily Life Sciences, South San Francisco, CA, USA., Snoad N; Verily Life Sciences, South San Francisco, CA, USA., Upson L; Verily Life Sciences, South San Francisco, CA, USA., Holeman J; Consolidated Mosquito Abatement District, Parlier, CA, USA., Massaro P; Verily Life Sciences, South San Francisco, CA, USA., Dobson SL; MosquitoMate Inc., Lexington, KY, USA.; Department of Entomology, University of Kentucky, Lexington, KY, USA., Mulligan FS; Consolidated Mosquito Abatement District, Parlier, CA, USA., White BJ; Verily Life Sciences, South San Francisco, CA, USA. bradwhite@verily.com.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2022 Oct; Vol. 40 (10), pp. 1443-1446. Date of Electronic Publication: 2022 May 26.

T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study.

Autor: Angyal A; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Longet S; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Moore SC; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Payne RP; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Harding A; Sir William Dunn School of Pathology, Division of Medical Sciences, University of Oxford, Oxford, UK., Tipton T; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Rongkard P; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Centre For Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand., Ali M; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Centre For Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Hering LM; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Meardon N; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Austin J; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Brown R; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Skelly D; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Gillson N; Public Health England, Colindale, London, UK., Dobson SL; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Cross A; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK., Sandhar G; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Kilby JA; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Tyerman JK; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Nicols AR; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Spegarova JS; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University, Newcastle, UK., Mehta H; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Hornsby H; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Whitham R; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Conlon CP; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Jeffery K; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Goulder P; Peter Medawar Building for Pathogen Research, Department of Paediatrics, University of Oxford, Oxford, UK., Frater J; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Pace M; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Ogbe A; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Brown H; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Ansari MA; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Adland E; Peter Medawar Building for Pathogen Research, Department of Paediatrics, University of Oxford, Oxford, UK., Brown A; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Chand M; Public Health England, Colindale, London, UK., Shields A; Institute of Cancer and Genomic Science, College of Medical and Dental Science, University of Birmingham, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Matthews PC; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Hopkins S; NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, University of Oxford, Oxford, UK.; Public Health England, Colindale, London, UK.; Faculty of Medicine, Department of Infectious Disease, Imperial College London, London, UK., Hall V; NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, University of Oxford, Oxford, UK.; Public Health England, Colindale, London, UK., James W; Sir William Dunn School of Pathology, Division of Medical Sciences, University of Oxford, Oxford, UK., Rowland-Jones SL; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Klenerman P; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Dunachie S; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Centre For Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Richter A; Institute of Cancer and Genomic Science, College of Medical and Dental Science, University of Birmingham, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Duncan CJA; Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University, Newcastle, UK.; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK., Barnes E; Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Carroll M; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Turtle L; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; Tropical and Infectious Disease Unit, Liverpool University Hospitals NHS Foundation Trust, member of Liverpool Health Partners, Liverpool, UK., de Silva TI; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Publikováno v: The Lancet. Microbe [Lancet Microbe] 2022 Jan; Vol. 3 (1), pp. e21-e31. Date of Electronic Publication: 2021 Nov 09.