Dynamic mechanochemical feedback between curved membranes and BAR protein self-organization

Autor: Anabel-Lise Le Roux, Caterina Tozzi, Nikhil Walani, Xarxa Quiroga, Dobryna Zalvidea, Xavier Trepat, Margarita Staykova, Marino Arroyo, Pere Roca-Cusachs

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Amphiphysin BAR proteins reshape membranes, but the dynamics of the process remained unexplored. Here, the authors show through experiment and modelling that reshaping depends on the initial template shape, occurs even at low initial curvature, and i

Externí odkaz: https://doaj.org/article/3b9d4c84264247a5a7e94d78fc4c48cf

The Combined Use of Gold Nanoparticles and Infrared Radiation Enables Cytosolic Protein Delivery

Autor: Dobryna Zalvidea, Josep Garcia, J. Marcos Fernández-Pradas, Marcelo J. Kogan, Pere Serra, Anna Lladó, Ernest Giralt, Macarena Sánchez-Navarro

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 27(14)

Cytosolic protein delivery remains elusive. The inability of most proteins to cross the cellular membrane is a huge hurdle. Here we explore the unique photothermal properties of gold nanorods (AuNRs) to trigger cytosolic delivery of proteins. Both pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d29d11d5c0b75d2bdab673dc4dec1c
https://pubmed.ncbi.nlm.nih.gov/33368712

Dynamic Mechanochemical feedback between curved membranes and BAR protein self-organization

Autor: Nikhil Walani, Anabel-Lise Le Roux, Marino Arroyo, Xarxa Quiroga, Caterina Tozzi, Dobryna Zalvidea, Margarita Staykova, Pere Roca-Cusachs, Xavier Trepat

Publikováno v: bioRxiv
Nature Communications
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, 2021, Vol.12, pp.6550 [Peer Reviewed Journal]
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Reproducció del document publicat a: https://doi.org/10.1038/s41467-021-26591-3
In many physiological situations, BAR proteins reshape membranes with pre-existing curvature (templates), contributing to essential cellular processes. However, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8c7b9f02e799a765401d8384666546

Time-Lapse Intravital Imaging of Biomaterials Integration in Tissues using a Multicolor Multiphoton Microscope

Autor: Sandra Baker, Natalia Castro, Xavier Trepat, Oscar Castaño, Dobryna Zalvidea, Elisabeth Engel

Publikováno v: 2019 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC).

Different mechanisms are triggered when tissue is exposed to a biomaterial. The success of the biomaterial targeted process, like the release of chemicals, promoted angiogenesis, tissue regeneration, etc. depends on its integration in the tissue [1].

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::646f8ef180e36bdd5397b583657333f0
https://doi.org/10.1109/cleoe-eqec.2019.8872718

Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells

Autor: Carolina Tarantino, Dobryna Zalvidea, Pere Roca-Cusachs, Juan Carlos Izpisua Belmonte, Nuria Montserrat, Josep M. Campistol, Lucia Fanlo, Elena Garreta, Elisa Martí, Luca Cozzuto, Aleix Gavaldà-Navarro, Roger Oria, Patrícia Rezende do Prado, Xavier Trepat, Carmen Hurtado del Pozo

Publikováno v: Nature Materials
Dipòsit Digital de la UB
Universidad de Barcelona
Nat Mater
Digital.CSIC. Repositorio Institucional del CSIC
instname

The generation of organoids is one of the biggest scientific advances in regenerative medicine. Here, by lengthening the time that human pluripotent stem cells (hPSCs) were exposed to a three-dimensional microenvironment, and by applying defined rena

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7ab1e49a93f65f57cfa2e8664b1b17