Tezacaftor is a direct inhibitor of sphingolipid delta-4 desaturase enzyme (DEGS)

Autor: Ciobanu, Dinu Zinovie, Liessi, Nara, Tomati, Valeria, Capurro, Valeria, Bertozzi, Sine Mandrup, Summa, Maria, Bertorelli, Rosalia, Loberto, Nicoletta, Dobi, Dorina, Aureli, Massimo, Nobbio, Lucilla, Bandiera, Tiziano, Pedemonte, Nicoletta, Bassi, Rosaria, Armirotti, Andrea

Publikováno v: In Journal of Cystic Fibrosis November 2024 23(6):1167-1172

Gangliosides and Cell Surface Ganglioside Metabolic Enzymes in the Nervous System.

Autor: Aureli M; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy., Mauri L; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy., Carsana EV; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy., Dobi D; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy., Breviario S; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy., Lunghi G; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy., Sonnino S; Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Italy. sandro.sonnino@unimi.it.

Publikováno v: Advances in neurobiology [Adv Neurobiol] 2023; Vol. 29, pp. 305-332.