Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Doak BC"'
Autor:
Mohanty, B, Orts, J, Wang, Geqing, Nebl, S, Alwan, WS, Doak, BC, Williams, ML, Heras, Begona, Mobli, M, Scanlon, MJ
Publikováno v:
Scientific Reports. 12
Structures of protein–ligand complexes provide critical information for drug design. Most protein–ligand complex structures are determined using X-ray crystallography, but where crystallography is not able to generate a structure for a complex, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8af36583a9bcb30933bbdc0e8653d5
https://doi.org/10.1038/s41598-022-13561-y
https://doi.org/10.1038/s41598-022-13561-y
Autor:
Doak BC; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Whitehouse RL; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Rimmer K; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Williams M; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Heras B; Department of Biochemistry and Genetics, La Trobe, La Trobe University, Kingsbury Drive, Bundoora, Vic, 3083, Australia., Caria S; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Ilyichova O; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Vazirani M; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Mohanty B; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.; Sydney Analytical Core Research Facility, The University of Sydney, Sydney, New South Wales, 2006, Australia., Harper JB; School of Chemistry, University of New South Wales, Sydney, NSW, 2052, Australia., Scanlon MJ; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.; Sydney Analytical Core Research Facility, The University of Sydney, Sydney, New South Wales, 2006, Australia., Simpson JS; Medicinal Chemistry, ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.
Publikováno v:
ChemMedChem [ChemMedChem] 2024 Aug 19; Vol. 19 (16), pp. e202300684. Date of Electronic Publication: 2024 Jul 08.
Autor:
Phan MQ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Chandrashekaran IR; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Akhtar N; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Konstantinidou E; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Devine SM; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Doak BC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Nebl T; Biologics Research and Development Group, Biomedical Manufacturing Program, CSIRO, Clayton, Victoria 3168, Australia., Creek DJ; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Norton RS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Jun 17; Vol. 15 (7), pp. 1071-1079. Date of Electronic Publication: 2024 Jun 17 (Print Publication: 2024).
Autor:
Adams LA; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia., Wilkinson-White LE; Sydney Analytical Core Research Facility, University of Sydney, Camperdown, NSW 2006, Australia., Gunzburg MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia., Headey SJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia., Mohanty B; Sydney Analytical Core Research Facility, University of Sydney, Camperdown, NSW 2006, Australia., Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia., Capuano B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia., Mackay JP; School of Life and Environmental Sciences, University of Sydney, Camperdown 2006, NSW, Australia., Doak BC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Apr 27; Vol. 66 (8), pp. 5859-5872. Date of Electronic Publication: 2023 Apr 18.
Autor:
Whitehouse RL; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu., Alwan WS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu., Ilyichova OV; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu.; Australian Synchrotron, ANSTO Clayton VIC 3168 Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia., Taylor AJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu., Chandrashekaran IR; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia.; Monash Fragment Platform, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia., Mohanty B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu., Doak BC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia.; Monash Fragment Platform, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia., Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia martin.scanlon@monash.edu.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia.; Monash Fragment Platform, Monash Institute of Pharmaceutical Sciences, Monash University Parkville VIC 3052 Australia.
Publikováno v:
RSC medicinal chemistry [RSC Med Chem] 2022 Nov 29; Vol. 14 (1), pp. 135-143. Date of Electronic Publication: 2022 Nov 29 (Print Publication: 2023).
Autor:
Wang G; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, 3083, Melbourne, Victoria, Australia., Mohanty B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia.; Current Address: Sydney Analytical Core Research Facility, The University of Sydney, 2006, Sydney, New South Wales, Australia., Williams ML; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia., Doak BC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia., Dhouib R; Queensland University of Technology, Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Brisbane, Queensland, Australia., Totsika M; Queensland University of Technology, Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Brisbane, Queensland, Australia., McMahon RM; Griffith Institute for Drug Discovery, Griffith University, 4111, Nathan, Queensland, Australia., Sharma G; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia., Zheng D; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia., Bentley MR; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia., Ka-Yan Chin Y; Institute for Molecular Bioscience, The University of Queensland, 4072, St Lucia, Queensland, Australia.; Centre for Advanced Imaging, The University of Queensland, 4072, St Lucia, Queensland, Australia., Horne J; Central Science Laboratory, The University of Tasmania, 7005, Sandy Bay, Tasmania, Australia., Chalmers DK; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia., Heras B; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, 3083, Melbourne, Victoria, Australia., Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052, Parkville, Victoria, Australia.
Publikováno v:
ChemMedChem [ChemMedChem] 2022 Mar 18; Vol. 17 (6), pp. e202100673. Date of Electronic Publication: 2022 Jan 27.
Autor:
Nebl S; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Alwan WS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Williams ML; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Sharma G; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Taylor A; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Doak BC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Wilde KL; National Deuteration Facility, Australian Nuclear Science and Technology Organization (ANSTO), Locked Bag 2001, Kirrawee DC, NSW, 2232, Australia., McMahon RM; Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia., Halili MA; Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia., Martin JL; Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia.; Vice-Chancellor's Unit, University of Wollongong, Northfields Avenue, Wollongong, NSW, 2522, Australia., Capuano B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Fenwick RB; Department of Integrative Structural and Computational Biology, Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA., Mohanty B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia. biswaranjan.mohanty@monash.edu.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia. biswaranjan.mohanty@monash.edu., Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia. martin.scanlon@monash.edu.; ARC Centre for Fragment-Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia. martin.scanlon@monash.edu.
Publikováno v:
Journal of biomolecular NMR [J Biomol NMR] 2020 Nov; Vol. 74 (10-11), pp. 595-611. Date of Electronic Publication: 2020 Aug 06.
Autor:
Bentley MR; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Ilyichova OV; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Wang G; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia., Williams ML; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Sharma G; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Alwan WS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Whitehouse RL; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Mohanty B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Scammells PJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Heras B; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia., Martin JL; Griffith Institute for Drug Discovery, Building N75, Brisbane Innovation Park, Don Young Road, Nathan, QLD 4111, Australia.; Vice-Chancellor's Unit, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia., Totsika M; School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD 4059, Australia., Capuano B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Doak BC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.; Monash Fragment Platform, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia., Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.; ARC Training Centre for Fragment Based Design, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.; Monash Fragment Platform, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2020 Jul 09; Vol. 63 (13), pp. 6863-6875. Date of Electronic Publication: 2020 Jun 24.
Autor:
Tyagi M; Department of Chemistry-BMC, Uppsala University, Box 576, 75123, Uppsala, Sweden., Begnini F; Department of Chemistry-BMC, Uppsala University, Box 576, 75123, Uppsala, Sweden., Poongavanam V; Department of Chemistry-BMC, Uppsala University, Box 576, 75123, Uppsala, Sweden., Doak BC; Department of Medicinal Chemistry, MIPS, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia., Kihlberg J; Department of Chemistry-BMC, Uppsala University, Box 576, 75123, Uppsala, Sweden.
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Jan 02; Vol. 26 (1), pp. 49-88. Date of Electronic Publication: 2019 Oct 11.
Autor:
Patil R; From Medicinal Chemistry., Mohanty B; From Medicinal Chemistry., Liu B; Drug Delivery, Disposition and Dynamics, and., Chandrashekaran IR; From Medicinal Chemistry., Headey SJ; From Medicinal Chemistry., Williams ML; From Medicinal Chemistry., Clements CS; From Medicinal Chemistry., Ilyichova O; From Medicinal Chemistry., Doak BC; From Medicinal Chemistry., Genissel P; the Institut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France., Weaver RJ; the Institut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France., Vuillard L; the Institut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France., Halls ML; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia and michelle.halls@monash.edu., Porter CJH; Drug Delivery, Disposition and Dynamics, and chris.porter@monash.edu., Scanlon MJ; From Medicinal Chemistry, martin.scanlon@monash.edu.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2019 Mar 08; Vol. 294 (10), pp. 3720-3734. Date of Electronic Publication: 2018 Dec 31.