Výsledky vyhledávání - "Doaa S. El-Sayed"

Akademický článek

Experimental and theoretical quantum chemical studies of 2-(2-acetamidophenyl)-2-oxo-N-(pyridin-2-ylmethyl)acetamide and its copper(II) complex: molecular docking simulation of the designed coordinated ligand with insulin-like growth factor-1 receptor (IGF-1R)

Autor: Doaa S. El-Sayed, Leena Sinha, Amina A. Soayed

Publikováno v: BMC Chemistry, Vol 18, Iss 1, Pp 1-23 (2024)

Abstract Newly synthesized ligand 2-(2- acetamidophenyl)-2-oxo-N-(pyridin-2-ylmethyl)acetamide and its copper(II) complex were characterized by elemental analyses, FT-IR, UV–Vis., ESR, 1H-NMR, and thermal analysis along with the theoretical quantum

Externí odkaz: https://doaj.org/article/cc603fb1aec344e5bd7297586810ab75

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

A perception into binary and ternary copper (II) complexes: synthesis, characterization, DFT modeling, antimicrobial activity, protein binding screen, and amino acid interaction

Autor: Doaa S. El-Sayed, Eman M. Tawfik, Amel F. Elhusseiny, Ali El-Dissouky

Publikováno v: BMC Chemistry, Vol 17, Iss 1, Pp 1-20 (2023)

Abstract Ensuring healthy lives and promoting well-being for all at all ages is the third goal of the sustainable development plan, so it was necessary to identify the most important problems that threaten health in our world. The World Health Organi

Externí odkaz: https://doaj.org/article/2c0ed717f0ac424597b88fba89a3f646

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2

Autor: Doaa S. El Sayed, El-Sayed M. Abdelrehim

Publikováno v: BMC Chemistry, Vol 16, Iss 1, Pp 1-18 (2022)

Abstract Computational tools in investigating of spectral heterocyclic compounds ranges based on pyrimidine‑2‑thiones, take some importance in identifying their molecular and electronic behavior. Some charcoal heterocyclic compounds were previous

Externí odkaz: https://doaj.org/article/1eeac6436b70412ba85806d149680e69

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Synthesis, screening as potential antitumor of new poly heterocyclic compounds based on pyrimidine-2-thiones

Autor: El-Sayed M. Abdelrehim, Doaa S. El-Sayed

Publikováno v: BMC Chemistry, Vol 16, Iss 1, Pp 1-15 (2022)

Abstract Background Continuing our interest in preparing of new heterocyclic compounds and examining their various biological activities, this work was designed to prepare new condensed and non-condensed heterocyclic compounds 9a-c, 10a-c, 11a-c, 13a

Externí odkaz: https://doaj.org/article/1b08f0f46dff413c83ba045b3271ce4c

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The Synergistic Influence of Polyflavonoids from Citrus aurantifolia on Diabetes Treatment and Their Modulation of the PI3K/AKT/FOXO1 Signaling Pathways: Molecular Docking Analyses and In Vivo Investigations

Autor: Mohamed A. Hassan, Ghada M. Abd Elmageed, Ibtehal G. El-Qazaz, Doaa S. El-Sayed, Lamia M. El-Samad, Heba M. Abdou

Publikováno v: Pharmaceutics, Vol 15, Iss 9, p 2306 (2023)

This study was aimed at probing the modulatory influence of polyflavonoids extracted from Citrus aurantifolia, lemon peel extract (LPE-polyflavonoids), on attenuating diabetes mellitus (DM) and its complications. HPLC investigations of the LPE exhibi

Externí odkaz: https://doaj.org/article/ca931e1868644c7cbcd6902c783aa8eb

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Entomotherapeutic Role of Periplaneta americana Extract in Alleviating Aluminum Oxide Nanoparticles-Induced Testicular Oxidative Impairment in Migratory Locusts (Locusta migratoria) as an Ecotoxicological Model

Autor: Esraa A. Arafat, Doaa S. El-Sayed, Hussein K. Hussein, Justin Flaven-Pouchon, Bernard Moussian, Lamia M. El-Samad, Abeer El Wakil, Mohamed A. Hassan

Publikováno v: Antioxidants, Vol 12, Iss 3, p 653 (2023)

In this study, we shed light for the first time on the usage of migratory locusts (Locusta migratoria) as an insect model to investigate the nanotoxicological influence of aluminum oxide (Al2O3) nanoparticles at low doses on testes, and evaluate the

Externí odkaz: https://doaj.org/article/97875d98335b4ec1bf8c5084665e7898

Zobrazit plný text záznamu

Geometric Isomerism and DFT Theoretical Explanation of the Unexpected Formation of N, N-disubstituted Formamidines from 2-amino-3-cyano-4.6- diarylpyridines

Autor: El-sayed M. Abdelrehim, Doaa S. El-Sayed

Publikováno v: Current Chinese Chemistry. 1:21-29

Introduction:Unexpected series of N,N-disubstituted formamidines were obtained upon the reaction of 2-amino-3-cyano-4.6-diarylpyridines with triflouroroacetic anhydride (TFAA) in dimethyl formamide (DMF).Methods:The syn/anti ratio of N,N-disubstitute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::462dcb6886413d8cb4810175259a96ce
https://doi.org/10.2174/2666001601666200123150220

Zobrazit plný text záznamu

A New Synthesis of Poly Heterocyclic Compounds Containing [1,2,4]triazolo and [1,2,3,4]tetrazolo Moieties and their DFT Study as Expected Anti-cancer Reagents

Autor: Doaa S. El-Sayed, El-sayed M. Abdelrehim

Publikováno v: Current Organic Synthesis. 17:211-223

Background:2-amino-3-cyanopyridines are good starting reagents that have been used in synthesis of many heterocyclic compounds such as pyridopyrimidines, [1,2,4]triazolo and [1,2,3,4] tetrazolo derivatives which have biological activities as anti-mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7265eff0fd22068bbac617a965abc716
https://doi.org/10.2174/1570179417666200226092516

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání