Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Doaa M. Ali"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Autophagy is a highly conserved multistep process and functions as passage for degrading and recycling protein aggregates and defective organelles in eukaryotic cells. Based on the nature of these materials, their size and degradation rate, four type
Externí odkaz:
https://doaj.org/article/e39a27b5fe30433aa06d76f95f21fd22
Autor:
Mohamed R. Mahdi, Rania B. Georges, Doaa M. Ali, Raouf F. Bedeer, Huda M. Eltahry, Abd-El Hakiem Z. Gabr, Martin R. Berger
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Targeting of endothelin system genes is a promising strategy in cancer therapy. The modulation of these genes was explored in a model of colorectal cancer (CRC) liver metastasis and in a panel of CRC tumor cell lines that were exposed to the demethyl
Externí odkaz:
https://doaj.org/article/ae5ae01b0b0643ebbeb4a6047ab9b0a4
Objective The current study aims to evaluate the utility of impression cytology in the diagnosis of ocular surface alterations in multiple sclerosis patients as well as to connect impression cytology results with symptoms and clinical evaluation data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41752ee4bcc829c822686d6a95e1d522
https://doi.org/10.21203/rs.3.rs-2111300/v1
https://doi.org/10.21203/rs.3.rs-2111300/v1
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-15 (2019)
Cell Death Discovery
Cell Death Discovery
Pancreatic ductal adenocarcinoma (PDAC) shows a high level of basal autophagy. Here we investigated the role of optineurin (OPTN) in PDAC cell lines, which is a prominent member of the autophagy system. To that purpose, mining of publically available
Publikováno v:
Cellular Oncology. 42:93-106
Bone metastasis is observed in up to 70% of breast cancer patients. The currently available treatment options are palliative in nature. Chemokine receptor 5 (CCR5) has gained attention as therapeutic target in various malignancies. Here, we investiga
Autor:
Doaa M. Ali, Raouf Fekry Bedeer, Abd-El Hakiem Zohry Gabr, Mohamed R. Mahdi, Huda Eltahry, Martin R. Berger, Rania Georges
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
Targeting of endothelin system genes is a promising strategy in cancer therapy. The modulation of these genes was explored in a model of colorectal cancer (CRC) liver metastasis and in a panel of CRC tumor cell lines that were exposed to the demethyl
Autor:
Doaa M. Ali, Himanshu Soni, Hansjörg Eibl, Björn Tews, Martin R. Berger, Ashwini Kumar Sharma, Rainer König, Shariq S. Ansari
Publikováno v:
Cell Death and Disease, Vol 9, Iss 3, Pp 1-15 (2018)
Cell Death & Disease
Cell Death & Disease
Endoplasmic reticulum (ER) plays an essential role in cell function and survival. Accumulation of unfolded or misfolded proteins in the lumen of the ER activates the unfolded protein response (UPR), resulting in ER stress and subsequent apoptosis. Th
Autor:
Doaa M. Ali, Michael Zepp, Martin R. Berger, Maria Nikolova, Matthias Bozza, Richard Harbottle
Publikováno v:
Cancer Research. 80:4717-4717
Ly6/neurotoxin1 (Lynx1) functions as a brake for nicotinic receptors and was defined as a tumor suppressor in lung cancer. As pancreatic cancer development may be slowed down by cholinergic signaling, we investigated the role of Lynx1 in pancreatic d
Publikováno v:
Cancer Research. 79:4836-4836
Ly6/neurotoxin1 (Lynx1) is a cholinergic transmission modulator, which was described as a tumor suppressor in lung cancer. In addition, the expression of Lynx1 was downregulated in rat PDAC cells colonizing rat liver. As cholinergic signaling via the