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Autor:
Le-Quang Bao, Daniel Baecker, Do Thi Mai Dung, Nguyen Phuong Nhung, Nguyen Thi Thuan, Phuong Linh Nguyen, Phan Thi Phuong Dung, Tran Thi Lan Huong, Bakhtiyor Rasulev, Gerardo M. Casanola-Martin, Nguyen-Hai Nam, Hai Pham-The
Publikováno v:
Molecules, Vol 28, Iss 8, p 3588 (2023)
Multi-target drug development has become an attractive strategy in the discovery of drugs to treat of Alzheimer’s disease (AzD). In this study, for the first time, a rule-based machine learning (ML) approach with classification trees (CT) was appli
Externí odkaz:
https://doaj.org/article/8cfc16ca2eb94431aa56e4e89c8c4ffd
Autor:
Le Cong Huan, Duong Tien Anh, Pham-The Hai, Lai Duc Anh, Eun Jae Park, A Young Ji, Jong Soon Kang, Do Thi Mai Dung, Dao Thi Kim Oanh, Truong Thanh Tung, Dinh Thi Thanh Hai, Sang-Bae Han, Nguyen-Hai Nam
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1854-1865 (2020)
In continuity of our search for novel anticancer agents acting as procaspase activators, we have designed and synthesised two series of (E)-N′-benzylidene-carbohydrazides (4a–m) and (Z)-N'-(2-oxoindolin-3-ylidene)carbohydrazides (5a–g) incorpor
Externí odkaz:
https://doaj.org/article/3162c7d7619043d19071ab32e4c93f8b
Publikováno v:
Pharmacy, Vol 10, Iss 6, p 146 (2022)
During the global COVID pandemic, the importance of professionals in the health care sector has been put in a new light, including pharmacists. In this context, the focus is also on how pharmacists are trained in different countries. Through an excha
Externí odkaz:
https://doaj.org/article/9d09b7d5d7b847d58a7bad40b068407e
Autor:
Do Thi Mai Dung, Phan Thi Phuong Dung, Dao Thi Kim Oanh, Tran Khac Vu, Hyunggu Hahn, Byung Woo Han, Minji Pyo, Young Guk Kim, Sang-Bae Han, Nguyen-Hai Nam
Publikováno v:
Arabian Journal of Chemistry, Vol 10, Iss 4, Pp 465-472 (2017)
A series of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides were designed, synthesized and evaluated for histone deacetylase (HDAC) inhibition and cytotoxicity. It was found that the compounds in t
Externí odkaz:
https://doaj.org/article/e0efe2b3750d47eeb1373e91ec7b10c9