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of 2
pro vyhledávání: '"Do Hee Oh"'
Autor:
Seo-Jung Han, Jae Eun Jung, Do Hee Oh, Minsup Kim, Jae-Min Kim, Kyung-Sook Chung, Hee-Soo Han, Jeong-Hun Lee, Kyung-Tae Lee, Hee Jin Jeong, In Ho Park, Eunkyeong Jeon, Jeon-Soo Shin, Dongkeun Hwang, Art E. Cho, Duck-Hyung Lee, Taebo Sim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1257-1277 (2022)
Identification of highly selective type II kinase inhibitors is described. Two different chiral peptidomimetic scaffolds were introduced on the tail region of non-selective type II kinase inhibitor GNF-7 to enhance the selectivity. Kinome-wide select
Externí odkaz:
https://doaj.org/article/c5691771b8354940857012412b9bca79
Autor:
Jae Eun Jung, Yunseong Jang, Hee Jin Jeong, Sung Joon Kim, Kichul Park, Do Hee Oh, Ahran Yu, Chan Sun Park, Seo-Jung Han
Publikováno v:
Bioorganicmedicinal chemistry letters. 75
Ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) negatively regulates the anti-cancer Stimulator of Interferon Genes (STING) pathway. We discovered that 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one and 3,4-dihydropyrido[2,3-d]pyrimidin-2(1