[Immunization witha synthetic fragment 155-164 of neurotrophin receptor p75 prevents memory loss and decreases beta-amyloid level in mice with experimentally induced Alzheimer's disease]

Autor: Om, Vol Pina, Ni, Medvinskaia, Anna Kamynina, Zaporozhskaia IaV, Aleksandrova IIu, Do, Koroev, An, Samokhin, Td, Volkova, As, Arsen Ev, Nv, Bobkova

Publikováno v: Europe PubMed Central

Neurotoxic beta-amyloid peptide plays an important role in the pathology of Alzheimer's disease. In aggregated form it binds to several proteins on the surface of the brain cells leading to their death. p75 receptor in- volved in supporting of cell b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bb5b23aa11ba7aa0e63961ecfeb156dd
http://europepmc.org/abstract/med/25898755

Proteolytic degradation patterns of the receptor for advanced glycation end products peptide fragments correlate with their neuroprotective activity in Alzheimer's disease models.

Autor: Volpina OM; Department of Molecular Neurobiology, Laboratory of Synthetic Vaccines, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (RAS), Moscow, Russia., Koroev DO; Department of Molecular Neurobiology, Laboratory of Synthetic Vaccines, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (RAS), Moscow, Russia., Serebryakova MV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia., Volkova TD; Department of Molecular Neurobiology, Laboratory of Synthetic Vaccines, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (RAS), Moscow, Russia., Kamynina AV; Department of Molecular Neurobiology, Laboratory of Synthetic Vaccines, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (RAS), Moscow, Russia.; Research Center for Molecular Mechanisms of Aging and Age Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia., Bobkova NV; Laboratory of Cellular Mechanisms of Memory Pathology, Institute of Cell Biophysics (RAS), Pushchino, Russia.

Publikováno v: Drug development research [Drug Dev Res] 2021 Dec; Vol. 82 (8), pp. 1217-1226. Date of Electronic Publication: 2021 May 31.

New generation CPPs show distinct selectivity for cancer and noncancer cells.

Autor: Tansi FL; Department of Experimental Radiology, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany., Filatova MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Koroev DO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Volpina OM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Lange S; Jena Bioscience GmbH, Jena, Germany., Schumann C; Ernst-Abbe-University of Applied Sciences, Jena, Germany., Teichgräber UK; Department of Experimental Radiology, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany., Reissmann S; Jena Bioscience GmbH, Jena, Germany.; Centrum of Molecular Biomedicine, Institute of Biochemistry and Biophysics, Friedrich-Schiller-University, Jena, Germany., Hilger I; Department of Experimental Radiology, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany.

Publikováno v: Journal of cellular biochemistry [J Cell Biochem] 2019 Apr; Vol. 120 (4), pp. 6528-6541. Date of Electronic Publication: 2018 Oct 25.

Synthetic Fragment of Receptor for Advanced Glycation End Products Prevents Memory Loss and Protects Brain Neurons in Olfactory Bulbectomized Mice.

Autor: Volpina OM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Samokhin AN; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia., Koroev DO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Nesterova IV; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia., Volkova TD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Medvinskaya NI; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia., Nekrasov PV; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia., Tatarnikova OG; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia., Kamynina AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Balasanyants SM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Voronina TA; London Neurology and Pain Clinic, London, UK., Kulikov AM; Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia., Bobkova NV; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia.

Publikováno v: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2018; Vol. 61 (3), pp. 1061-1076.

[Fragment of Receptor for Advanced Glycation End Products Improves Memory State in a Model of Alzheimer's Disease].

Autor: Volpina OM, Koroev DO, Volkova TD, Kamynina AV, Filatova MP, Zaporozhskayva YV, Samokhin AN, Aleksandrova IJ, Bobkova NV

Publikováno v: Bioorganicheskaia khimiia [Bioorg Khim] 2015 Nov-Dec; Vol. 41 (6), pp. 709-16.