Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dmytro Royzman"'
Autor:
Pia Sinner, Katrin Peckert-Maier, Hashem Mohammadian, Christine Kuhnt, Christina Draßner, Vasiliki Panagiotakopoulou, Simon Rauber, Mathias Linnerbauer, Zhana Haimon, Dmytro Royzman, Deborah Kronenberg-Versteeg, Andreas Ramming, Alexander Steinkasserer, Andreas B. Wild
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Microglial activation during neuroinflammation is crucial for coordinating the immune response against neuronal tissue, and the initial response of microglia determines the severity of neuro-inflammatory diseases. The CD83 molecule has been
Externí odkaz:
https://doaj.org/article/9a4547d3e8bc4990bcfb3139d1b9c766
Autor:
Julia Elrod, Annika Heuer, Jasmin Knopf, Janina Schoen, Lavinia Schönfeld, Magdalena Trochimiuk, Carolin Stiel, Birgit Appl, Laia Pagerols Raluy, Ceren Saygi, Leticija Zlatar, Sami Hosari, Dmytro Royzman, Thomas H. Winkler, Günter Lochnit, Moritz Leppkes, Robert Grützmann, Georg Schett, Christian Tomuschat, Konrad Reinshagen, Martin Herrmann, Tobias A. Fuchs, Michael Boettcher
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108289- (2023)
Summary: Peritoneal adhesions are poorly understood but highly prevalent conditions that can cause intestinal obstruction and pelvic pain requiring surgery. While there is consensus that stress-induced inflammation triggers peritoneal adhesions, the
Externí odkaz:
https://doaj.org/article/ad7108bd59b349819ad23b8152735d57
Autor:
Katrin Peckert-Maier, Andreas B. Wild, Laura Sprißler, Maximilian Fuchs, Philipp Beck, Jean-Philippe Auger, Pia Sinner, Astrid Strack, Petra Mühl-Zürbes, Ntilek Ramadan, Meik Kunz, Gerhard Krönke, Lena Stich, Alexander Steinkasserer, Dmytro Royzman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Alterations in macrophage (Mφ) polarization, function, and metabolic signature can foster development of chronic diseases, such as autoimmunity or fibrotic tissue remodeling. Thus, identification of novel therapeutic agents that modulate human Mφ b
Externí odkaz:
https://doaj.org/article/ebaecb1fe44b410fa7de1e8626ca690e
Autor:
Marina A. Korn, Marie Steffensen, Carolin Brandl, Dmytro Royzman, Christoph Daniel, Thomas H. Winkler, Lars Nitschke
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Systemic lupus erythematosus (SLE) is a severe autoimmune disease that displays considerable heterogeneity not only in its symptoms, but also in its environmental and genetic causes. Studies in SLE patients have revealed that many genetic variants co
Externí odkaz:
https://doaj.org/article/64c20df68051432f9f311146a4f6e232
Autor:
Katrin Peckert-Maier, Pia Langguth, Astrid Strack, Lena Stich, Petra Mühl-Zürbes, Christine Kuhnt, Christina Drassner, Elisabeth Zinser, Marius Wrage, Jochen Mattner, Alexander Steinkasserer, Dmytro Royzman, Andreas B. Wild
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Excessive macrophage (Mφ) activation results in chronic inflammatory responses or autoimmune diseases. Therefore, identification of novel immune checkpoints on Mφ, which contribute to resolution of inflammation, is crucial for the development of ne
Externí odkaz:
https://doaj.org/article/1a0d798c26b848068ab4b38b25d588a3
Autor:
Dmytro Royzman, Katrin Peckert-Maier, Lena Stich, Christina König, Andreas B. Wild, Miyuki Tauchi, Christian Ostalecki, Franklin Kiesewetter, Stefan Seyferth, Geoffrey Lee, Sabine A. Eming, Maximilian Fuchs, Meik Kunz, Ewa K. Stürmer, Eva M. J. Peters, Carola Berking, Elisabeth Zinser, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
To facilitate the recovery process of chronic and hard-to-heal wounds novel pro-resolving treatment options are urgently needed. We investigated the pro-regenerative properties of soluble CD83 (sCD83) on cutaneous wound healing, where sCD83 accelerat
Externí odkaz:
https://doaj.org/article/1c5189c1d0044a92a854191e8b60e1a3
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp
Externí odkaz:
https://doaj.org/article/576ad5b73c124cb0990703d4d392cc97
Autor:
Atefeh Sadeghi Shermeh, Dmytro Royzman, Christine Kuhnt, Christina Draßner, Lena Stich, Alexander Steinkasserer, Ilka Knippertz, Andreas B. Wild
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7801 (2023)
The aryl hydrocarbon receptor (AhR) is a decisive regulatory ligand-dependent transcription factor. It binds highly diverse ligands, which can be categorized as either endogenous or exogenous. Ligand binding activates AhR, which can adjust inflammato
Externí odkaz:
https://doaj.org/article/e1084f711d9943b8b8148b7b775394c3
Autor:
Linda Grosche, Ilka Knippertz, Christina König, Dmytro Royzman, Andreas B. Wild, Elisabeth Zinser, Heinrich Sticht, Yves A. Muller, Alexander Steinkasserer, Matthias Lechmann
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The CD83 molecule has been identified to be expressed on numerous activated immune cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils. Both isoforms of CD83, the membrane-bound as well as its soluble form are
Externí odkaz:
https://doaj.org/article/fb3c408893074d5eb6e59205ef14a175
Autor:
Katrin Peckert-Maier, Dmytro Royzman, Pia Langguth, Anita Marosan, Astrid Strack, Atefeh Sadeghi Shermeh, Alexander Steinkasserer, Elisabeth Zinser, Andreas B. Wild
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 732 (2022)
Chronic inflammatory diseases and transplant rejection represent major challenges for modern health care. Thus, identification of immune checkpoints that contribute to resolution of inflammation is key to developing novel therapeutic agents for those
Externí odkaz:
https://doaj.org/article/1904b414411546588e4f70ce77910035