Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dmytro Grygoryev"'
Autor:
Dmytro Grygoryev, Taelor Ekstrom, Elise Manalo, Jason M. Link, Amani Alshaikh, Dove Keith, Brittany L. Allen-Petersen, Brett Sheppard, Terry Morgan, Abdenour Soufi, Rosalie C. Sears, Jungsun Kim
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27221- (2024)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly intratumorally heterogeneous disease that includes several subtypes and is highly plastic. Effective gene delivery to all PDAC cells is essential for modulating gene expression and ident
Externí odkaz:
https://doaj.org/article/c2d0ac08375d4ae4ba0faf1e9613a512
Autor:
Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Mice expressing human amyloid precursor protein (APP) containing the dominant Swedish and Iberian mutations (AppNL–F) or also Arctic mutation (AppNL–G–F) show neuropathology and hippocampus-dependent cognitive impairments pertinent to Alzheimer
Externí odkaz:
https://doaj.org/article/720235d09cb84b38bf37d97d7ba676f3
Autor:
Jacob Raber, Andrea Fuentes Anaya, Eileen Ruth S. Torres, Joanne Lee, Sydney Boutros, Dmytro Grygoryev, Austin Hammer, Kristin D. Kasschau, Thomas J. Sharpton, Mitchell S. Turker, Amy Kronenberg
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The radiation environment astronauts are exposed to in deep space includes galactic cosmic radiation (GCR) with different proportions of all naturally occurring ions. To assist NASA with assessment of risk to the brain following exposure to a mixture
Externí odkaz:
https://doaj.org/article/c282b1f38a8544a29acca40403dea8cd
Autor:
Mitchell S Turker, Dmytro Grygoryev, Michael Lasarev, Anna Ohlrich, Furaha A Rwatambuga, Sorrel Johnson, Cristian Dan, Bradley Eckelmann, Gwen Hryciw, Jian-Hua Mao, Antoine M Snijders, Stacey Gauny, Amy Kronenberg
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180412 (2017)
Exposure to a small number of high-energy heavy charged particles (HZE ions), as found in the deep space environment, could significantly affect astronaut health following prolonged periods of space travel if these ions induce mutations and related c
Externí odkaz:
https://doaj.org/article/7896c04f12a2425ab32989f85400fb2b
Publikováno v:
Dose-Response, Vol 6 (2008)
Ionizing radiation-induced formation of genomic DNA damage can be modulated by nearby chemical species such as heavy metal ions, which can lead to non-linear dose response. To investigate this phenomenon, we studied cell survival and formation of 8-h
Externí odkaz:
https://doaj.org/article/b769f3af9e74426faa3b40137f6dab0a
Autor:
Dmytro Grygoryev, Taelor Ekstrom, Elise C. Manalo, Jason Link, Dove Keith, Brittany L. Allen-Petersen, Brett C. Sheppard, Terry Morgan, Rosalie Sears, Jungsun Kim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c2f76d88c4920c6318e9be6cccaf6b
https://doi.org/10.2139/ssrn.4424988
https://doi.org/10.2139/ssrn.4424988
Autor:
Thuy T.M. Ngo, Greg Donahue, Wenli Yang, Terry K. Morgan, Taelor Ekstrom, John Muschler, Dmytro Grygoryev, Kenneth S. Zaret, Jungsun Kim
Publikováno v:
Molecular Cancer Research. 19:1854-1867
Previous transcriptome studies of human pancreatic ductal adenocarcinoma (PDAC) compare non-cancerous pancreatic intraepithelial neoplasias (PanIN) with late-stage PDAC obtained from different patients, thus have limited ability to discern network dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddcb203bde265b71b8be24fdb60d18d4
https://doi.org/10.1158/1541-7786.mcr-21-0483
https://doi.org/10.1158/1541-7786.mcr-21-0483
Publikováno v:
Cancer Research. 82:B046-B046
Cancer cells undergo plasticity against stress for the survival of the fittest. Pancreatic ductal adenocarcinoma (PDAC) also shows intratumoral transcriptional heterogeneity with cell plasticity, which correlates with phenotypical aggressiveness and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4789061f4f130affdce84a1d34204908
https://doi.org/10.1158/1538-7445.panca22-b046
https://doi.org/10.1158/1538-7445.panca22-b046
Autor:
Ayaka Kukino, Dmytro Grygoryev, Michael R. Rountree, Matthew P. Butler, Charles N. Allen, Anna Ohlrich, Mitchell S. Turker, Furaha A. Rwatambuga
Publikováno v:
J Biol Rhythms
Mammalian tissues display circadian rhythms in transcription, translation, and histone modifications. Here we asked how an advance of the light-dark cycle alters daily rhythms in the liver epigenome at the H3K4me3 (trimethylation of lysine 4 on histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4d410fe2d99f56ad0c84f6e62b57f7
https://doi.org/10.1177/0748730418779958
https://doi.org/10.1177/0748730418779958
Publikováno v:
Cancer Research. 81:PO-082
Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed at advanced stages rendering the already limited therapeutic options ineffective for many patients. Earlier diagnosis permits for “curative” surgery; however, 95% of these patients experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea4caaedb9c5cbdc6551b239cdefd22
https://doi.org/10.1158/1538-7445.panca21-po-082
https://doi.org/10.1158/1538-7445.panca21-po-082