Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dmytro, Kovalskyy"'
Autor:
Patrick J. Conway, Bárbara De La Peña Avalos, Jonathan Dao, Sebastian Montagnino, Dmytro Kovalskyy, Eloise Dray, Daruka Mahadevan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 55, Iss , Pp 101014- (2024)
Chemotherapy induced polyploidy is a mechanism of inherited drug resistance resulting in an aggressive disease course in cancer patients. Alisertib, an Aurora Kinase A (AK-A) ATP site inhibitor, induces cell cycle disruption resulting in polyaneuploi
Externí odkaz:
https://doaj.org/article/fdf3550c509b4ad3a071ef8341bf288c
Autor:
Thiruselvam Viswanathan, Shailee Arya, Siu-Hong Chan, Shan Qi, Nan Dai, Anurag Misra, Jun-Gyu Park, Fatai Oladunni, Dmytro Kovalskyy, Robert A. Hromas, Luis Martinez-Sobrido, Yogesh K. Gupta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Specific non-structural proteins (nsp) of SARS coronaviruses are involved in methylation of virally encoded mRNAs to mimic cellular mRNAs for protection against host innate immune restriction. Here, the authors present a high resolution structure of
Externí odkaz:
https://doaj.org/article/1a2c5dcfc62842e8b013e549e88fbd22
Autor:
Daniel O. Pinto, Tristan A. Scott, Catherine DeMarino, Michelle L. Pleet, Thy T. Vo, Mohammed Saifuddin, Dmytro Kovalskyy, James Erickson, Maria Cowen, Robert A. Barclay, Chen Zeng, Marc S. Weinberg, Fatah Kashanchi
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-17 (2019)
Abstract Background HIV-1 patients receiving combination antiretroviral therapy (cART) survive infection but require life-long adherence at high expense. In chronic cART-treated patients with undetectable viral titers, cell-associated viral RNA is st
Externí odkaz:
https://doaj.org/article/a041f36c688d441cbb365e5ac91b9eeb
Autor:
Awadh Alanazi, Andrey Ivanov, Namita Kumari, Xionghao Lin, Songping Wang, Dmytro Kovalskyy, Sergei Nekhai
Publikováno v:
Viruses, Vol 13, Iss 10, p 2004 (2021)
The HIV-1 Tat protein interacts with TAR RNA and recruits CDK9/cyclin T1 and other host factors to induce HIV-1 transcription. Thus, Tat–TAR RNA interaction, which is unique for HIV-1, represents an attractive target for anti-HIV-1 therapeutics. To
Externí odkaz:
https://doaj.org/article/8306fee3070542aab3c600b29a022a81
Autor:
Xionghao Lin, Tatiana Ammosova, Meng S. Choy, Colette A. Pietzsch, Andrey Ivanov, Asrar Ahmad, Yasemin Saygideğer, Namita Kumari, Dmytro Kovalskyy, Aykut Üren, Wolfgang Peti, Alexander Bukreyev, Sergei Nekhai
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Ebola virus (EBOV) is a non-segmented negative-sense RNA virus that causes a severe human disease. The ongoing EBOV outbreak in the Eastern part of Democratic Republic of the Congo has resulted to date in over 2500 confirmed cases including over 1500
Externí odkaz:
https://doaj.org/article/cef38a91be7c4905b107b9da78868f86
Autor:
Manjeet K. Rao, Jack L. Arbiser, Alexander J. Bishop, Yidong Chen, Ratna K. Vadlamudi, Martha A. Hanes, Dmitri Ivanov, Dmytro Kovalskyy, Benjamin Onyeagucha, Santosh Timilsina, Aparna Gorthi, Subbarayalu Panneerdoss, Subapriya Rajamanickam
Supplementary Fig. 1. IB inhibits the growth of breast cancer cells in a dose and time dependent manner. Supplementary Fig. 2. IB inhibits migration and invasion of breast cancer cells. Supplementary Fig. 3. IB treatment inhibits in vivo growth and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2725a96b211db403a5ae9b651db57f2d
https://doi.org/10.1158/1078-0432.22457699
https://doi.org/10.1158/1078-0432.22457699
Autor:
Manjeet K. Rao, Jack L. Arbiser, Alexander J. Bishop, Yidong Chen, Ratna K. Vadlamudi, Martha A. Hanes, Dmitri Ivanov, Dmytro Kovalskyy, Benjamin Onyeagucha, Santosh Timilsina, Aparna Gorthi, Subbarayalu Panneerdoss, Subapriya Rajamanickam
Purpose: The approaches aimed at inhibiting the ability of cancer cells to repair DNA strand breaks have emerged as promising targets for treating cancers. Here, we assessed the potential of imipramine blue (IB), a novel analogue of antidepressant im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc097ffe0614326027de178d2c877f6
https://doi.org/10.1158/1078-0432.c.6523658.v1
https://doi.org/10.1158/1078-0432.c.6523658.v1
Autor:
Manjeet K. Rao, Jack L. Arbiser, Alexander J. Bishop, Yidong Chen, Ratna K. Vadlamudi, Martha A. Hanes, Dmitri Ivanov, Dmytro Kovalskyy, Benjamin Onyeagucha, Santosh Timilsina, Aparna Gorthi, Subbarayalu Panneerdoss, Subapriya Rajamanickam
Supplimentary Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d53df3e8ffe6ce9422590135a02c193
https://doi.org/10.1158/1078-0432.22457696.v1
https://doi.org/10.1158/1078-0432.22457696.v1
Autor:
Manjeet K. Rao, Jack L. Arbiser, Alexander J. Bishop, Yidong Chen, Ratna K. Vadlamudi, Martha A. Hanes, Dmitri Ivanov, Dmytro Kovalskyy, Benjamin Onyeagucha, Santosh Timilsina, Aparna Gorthi, Subbarayalu Panneerdoss, Subapriya Rajamanickam
Supplementary Table S1: Primers used in the present investigation. Supplementary Table S 2 : Gene Ontology Enrichment Analysis on differentially expressed genes in IB-treated compared to vehicle-treated breast cancer cells using Database for Annotati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886931050fa15c9b2ed5330452f8c201
https://doi.org/10.1158/1078-0432.22457702
https://doi.org/10.1158/1078-0432.22457702
Autor:
Svitlana Chernii, Mykhaylo Losytskyy, Iryna Tretyakova, Maksym Kharchuk, Serhii Vakarov, Dmytro Kovalskyy, Yuriy Gerasymchyk, Vasyl Pekhnyo, Viktor Chernii, Vladyslava Kovalska
Publikováno v:
Proteins: Structure, Function, and Bioinformatics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05628a01f2f3358749722b1719ff36df
https://doi.org/10.1002/prot.26475
https://doi.org/10.1002/prot.26475