Výsledky vyhledávání - "Dmitry Yu. Gvaldin"

Identification of new candidate genes and signalling pathways associated with the development of neuroendocrine pancreatic tumours based on next generation sequencing data

Autor: Denis S. Kutilin, Vladimir Trifanov, Nataliya N. Timoshkina, Nataliya A. Petrusenko, Dmitry Yu. Gvaldin, Oleg I. Kit

Publikováno v: Molecular Biology Reports. 47:4233-4243

Despite advances in classification, treatment, and imaging, neuroendocrine tumours remain a clinically complex subject. In this work, we studied the genetic profile of well-differentiated pancreatic neuroendocrine tumours (PanNETs) in a cohort of Cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe9ea21cc8f8dab8e1ee2a09f328178f
https://doi.org/10.1007/s11033-020-05534-z

Zobrazit plný text záznamu

A clinical case of multiple primary cancers in a carrier of rare SDK2 and NOTCH2 gene mutations

Autor: Ekaterina P. Omelchuk, Emma E. Kechedzhieva, Nataliya N. Timoshkina, Oleg I. Kit, Tatjana V. Ausheva, Larisa N. Vashhenko, Dmitry Yu. Gvaldin

Publikováno v: Egyptian Journal of Medical Human Genetics, Vol 22, Iss 1, Pp 1-5 (2021)

Background Genetic predisposition is one of the risk factors for the development of multiple primary cancers (MPCs), the frequency of which increases and ranges from 2 to 17%. This study describes a combination of rare mutations, rs746551843 in the N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed110eff9c0ec9fb270b61d41e0ebb7
https://doi.org/10.1186/s43042-021-00176-7

Zobrazit plný text záznamu

SNP-SNP interactions and a 4-locus model for prediction the risk of anthracycline-mediated cardiotoxicity in patients with breast cancer

Autor: Dmitry Yu. Gvaldin, Natalya N. Timoshkina, Larisa N. Vashchenko, Tatiana V. Ausheva, Irina R. Dashkova, Ludmila A. Ryadinskaya, Emma E. Kechedzhieva, Liubov Yu Vladimirova

Publikováno v: Journal of Clinical Oncology. 40:12076-12076

12076 Background: Numerous pharmacogenetic studies have identified genetic polymorphisms (SNPs) associated with an increased risk of anthracycline-mediated cardiotoxicity (AMC). The purpose was to search for SNP-SNP interactions associated with the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9e9a454c45c048fb5ba0706a6c39679
https://doi.org/10.1200/jco.2022.40.16_suppl.12076

Zobrazit plný text záznamu

Polymorphism rs4673 and plasma paraoxonase 1 level for prediction and early diagnosis of anthracycline-mediated cardiotoxicity in patients with breast cancer

Autor: Dmitry Yu. Gvaldin, Natalya N. Timoshkina, Larisa N. Vashchenko, Tatiana V. Ausheva, Aleksandr B. Sagakyants, Oksana G. Shulgina, Irina R. Dashkova, Emma E. Kechedzhieva, Liubov Yu Vladimirova

Publikováno v: Journal of Clinical Oncology. 40:12077-12077

12077 Background: Anthracyclines are highly effective chemotherapeutic agents, used for a wide variety of malignancies. Despite their antitumor efficacy there is a risk of cardiotoxic manifestations that reduce the time and quality of life of patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e87085e509046c3f039c93720b82410
https://doi.org/10.1200/jco.2022.40.16_suppl.12077

Zobrazit plný text záznamu

BRCA1/2 genes mutations frequency in patients with various histological types of ovarian cancer (data for South of Russia)

Autor: Natalya N. Timoshkina, Natalia A. Petrusenko, Dmitry Yu. Gvaldin, Madina A. Gappoeva, Sergey E. Kavitskiy, Maria A. Cherkes, Ekaterina V. Verenikina, Denis S. Kutilin

Publikováno v: Journal of Clinical Oncology. 40:e17548-e17548

e17548 Background: About 10-15% of malignant ovarian tumors (OC) are associated with hereditary diseases, and about 65-85% of hereditary OC have a mutation in BRCA1/2 genes. The aim of the study was to analyze BRCA1/2 genes hereditary mutation spectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::661911e32650b5fc6f56927d16b58cf7
https://doi.org/10.1200/jco.2022.40.16_suppl.e17548

Zobrazit plný text záznamu

Integrative analysis of mRNA and miRNA sequencing data for gliomas of various grades

Autor: Arbi M. Nalgiev, Oleg I. Kit, Eduard E. Rostorguev, Nataliya N. Timoshkina, Anton A. Pushkin, Dmitry Yu. Gvaldin

Publikováno v: Egyptian Journal of Medical Human Genetics, Vol 21, Iss 1, Pp 1-17 (2020)

Background The purpose of this study was to characterize subtype-specific patterns of mRNA and miRNA expression of gliomas using The Cancer Genome Atlas (TCGA) data to search for genetic determinants that predict prognosis in terms of overall surviva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276da957a3046898289e090a88278e62
https://doi.org/10.1186/s43042-020-00119-8

Zobrazit plný text záznamu

Study of microsatellite instability in neuroendocrine tumors of pancreas and colon

Autor: Maksim N. Duritskiy, Vladimir Trifanov, Natalya N. Timoshkina, Petr N. Gabrichidze, Dmitry Yu. Gvaldin, Sergey V. Sanamyants, Oleg I. Kit, Stanislav Stanislavovich Mezentsev, Evgeniy N. Kolesnikov, Umar Muhmadovich Gaziev, Milana Yu. Mesheryakova

Publikováno v: Journal of Clinical Oncology. 39:e16196-e16196

e16196 Background: Microsatellite instability (MSI), as an acquired feature of malignant tumors, is a predictive and prognostic marker. The less aggressive nature of MSI-positive tumors has been associated with high immunogenicity. In the present stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c54b048f6d6c7afcf6474946e7a4aa7
https://doi.org/10.1200/jco.2021.39.15_suppl.e16196

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání