Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dmitry V. Sverchinsky"'
Autor:
Dmitry V. Sverchinsky, Bashar A. Alhasan, Marina A. Mikeladze, Vladimir F. Lazarev, Liubov S. Kuznetcova, Alisa V. Morshneva, Alina D. Nikotina, Amr Ziewanah, Lidia V. Koludarova, Tatiana Y. Starkova, Boris A. Margulis, Irina V. Guzhova
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Cancer recurrence is regulated by a variety of factors, among which is the material of dying tumor cells; it is suggested that remaining after anti-cancer therapy tumor cells receive a signal from proteins called damage-associated
Externí odkaz:
https://doaj.org/article/3ad6558362834740b4a23a796ea296c8
Autor:
Vladimir F. Lazarev, Pavel I. Semenyuk, Irina V. Guzhova, Dmitry V Sverchinsky, Boris A. Margulis, Vladimir A. Mitkevich
Publikováno v:
FEBS Letters. 591:4074-4082
Most Hsp70 chaperone inhibitors exert anti-cancer effects; however, their high cytotoxicity proposed the use of peptide fragments of the chaperone as safer modulators of its activity and as complements to customary drugs. One such peptide, ICit-2, wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6407acbf6168f1cbcf6ad68713780e7a
https://doi.org/10.1002/1873-3468.12913
https://doi.org/10.1002/1873-3468.12913
Autor:
Michael B. Evgen'ev, Boris A. Margulis, Vladimir A. Mitkevich, David G. Garbuz, Dmitry V Sverchinsky, Aleksei M Kulikov, Artem I. Davletshin
Publikováno v:
Cell Stress Chaperones
Previously, we demonstrated that species of the Stratiomyidae family exhibit higher tolerance to thermal stress in comparison with that of many representatives of Diptera, including Drosophila species. We hypothesized that species of this group inher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244208167db44e74c0b3a3eef8c59a65
https://pubmed.ncbi.nlm.nih.gov/31664698
https://pubmed.ncbi.nlm.nih.gov/31664698
Autor:
Dmitry V Sverchinsky, Boris A. Margulis, Vladimir Poroikov, Elena R. Mikhaylova, Irina V. Guzhova, Dmitry S. Druzhilovskiy, Vladimir F. Lazarev, Alina D. Nikotina, N. D. Aksenov, Vladimir A. Mitkevich, Elena Y. Komarova, Roman V. Suezov
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 9
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2519 (2018)
Volume 19
Issue 9
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2519 (2018)
The Hsp70 chaperone binds and inhibits proteins implicated in apoptotic signaling including Caspase-3. Induction of apoptosis is an important mechanism of anti-cancer drugs, therefore Hsp70 can act as a protective system in tumor cells against therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39814e2c2ca36ffda78dfa35560234b9
Autor:
Sergey A Niskanen, Vladimir F. Lazarev, A. V. Burakov, Irina V. Guzhova, Elena R. Mikhaylova, Elena Y. Komarova, Dmitry V Sverchinsky, Pavel I. Semenyuk, Viktor G Kartsev, Alina D. Nikotina, Boris A. Margulis
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-11 (2018)
Cell Death and Disease, Vol 9, Iss 2, Pp 1-11 (2018)
Hsp70 chaperone controls proteostasis and anti-stress responses in rapidly renewing cancer cells, making it an important target for therapeutic compounds. To date several Hsp70 inhibitors are presented with remarkable anticancer activity, however the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127a360275caf0a6d22976d3d2e9f719
https://pubmed.ncbi.nlm.nih.gov/29348557
https://pubmed.ncbi.nlm.nih.gov/29348557