Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dmitry V. Rozanov"'
Autor:
Berhane Ghebrehiwet, Dmitry V. Rozanov, Alex Y. Strongin, Andreas Eichinger, Elena I. Deryugina, Tatiana I. Postnova
Publikováno v:
Journal of Biological Chemistry. 277:9318-9325
Matrix metalloproteinases (MMPs) including membrane type 1 MMP (MT1-MMP) can degrade extracellular matrix and cell surface receptor molecules and have an essential function in malignancy. Recently, we established a functional link between MT1-MMP and
Autor:
Boris I. Ratnikov, James P. Quigley, Dmitry V. Rozanov, George N. Marchenko, Edward Monosov, Elena I. Deryugina, Alex Y. Strongin
Publikováno v:
Journal of Biological Chemistry. 276:25705-25714
Membrane type-1 matrix metalloproteinase (MT1-MMP) is a key enzyme in the activation pathway of matrix prometalloproteinase-2 (pro-MMP-2). Both activation and autocatalytic maturation of pro-MMP-2 in trans suggest that MT1-MMP should exist as oligome
Autor:
George N. MARCHENKO, Boris I. RATNIKOV, Dmitry V. ROZANOV, Adam GODZIK, Elena I. DERYUGINA, Alex Y. STRONGIN
Publikováno v:
Biochemical Journal. 356:705-718
Identification of expanding roles for matrix metalloproteinases (MMPs) in complex regulatory processes of tissue remodelling has stimulated the search for genes encoding proteinases with unique functions, regulation and expression patterns. By using
Publikováno v:
Journal of Bacteriology. 180:6306-6315
Autor:
Ya Chen, Maurizio Pellecchia, and Alex Y. Strongin, Dawoon Jung, Martino Forino, Arnold C. Satterthwait, Dmitry V. Rozanov, Sherida L. Johnson
Publikováno v:
Journal of medicinal chemistry. 49(1)
We have recently identified a series of compounds which efficiently inhibit Anthrax lethal factor (LF) metallo-protease. Here we present further structure activity relationship and CoMFA (Comparative Molecular Field Analysis) studies on newly derived
Publikováno v:
Journal of bacteriology. 180(23)
Two Escherichia coli genes, expressed from multicopy plasmids, are shown to cause partial induction of prophage λ in recA mutant lysogens. One is rcsA , which specifies a positive transcriptional regulator of the cps genes, which are involved in cap
Autor:
Elena I. Deryugina, Berhane Ghebrehiwet, Dmitry V. Rozanov, Boris I. Ratnikov, Alex Y. Strongin, Edward Monosov
Publikováno v:
FEBS Letters. (1-3):51-57
Membrane type-1 matrix metalloproteinase (MT1-MMP), a key enzyme in cell locomotion, is known to be primarily recruited to the leading edge of migrating cells. This raises a possibility that the C-terminal cytoplasmic tail of MT1-MMP interacts with i