Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Dmitry V Kuprash"'
Autor:
Marina A Afanasyeva, Lidia V Putlyaeva, Denis E Demin, Ivan V Kulakovskiy, Ilya E Vorontsov, Marina V Fridman, Vsevolod J Makeev, Dmitry V Kuprash, Anton M Schwartz
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172681 (2017)
We studied functional effect of rs12722489 single nucleotide polymorphism located in the first intron of human IL2RA gene on transcriptional regulation. This polymorphism is associated with multiple autoimmune conditions (rheumatoid arthritis, multip
Externí odkaz:
https://doaj.org/article/1b53b0d793e748d19e0ebb55e673d7eb
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Chemokine receptor CXCR5 is highly expressed in B-cells and under normal conditions is involved in their migration to specific areas of secondary lymphoid organs. B-cells are known to play an important role in various autoimmune diseases including mu
Externí odkaz:
https://doaj.org/article/53d355fc9caa4cc0aac2ca21a4435deb
Autor:
Kirill V Korneev, Nikolay P Arbatsky, Antonio eMolinaro, Angelo ePalmigiano, Rima Z Shaikhutdinova, Mikhail M Shneider, Gerald B Pier, Anna N Kondakova, Ekaterina N Sviriaeva, Luisa eSturiale, Domenico eGarozzo, Andrey A Kruglov, Sergei A Nedospasov, Marina S Drutskaya, Yuriy A Knirel, Dmitry V Kuprash
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Toll-like receptor 4 (TLR4) is required for activation of innate immunity upon recognition of lipopolysaccharide (LPS) of Gram-negative bacteria. The ability of TLR4 to respond to a particular LPS species is important since insufficient activation ma
Externí odkaz:
https://doaj.org/article/410565aab6c147da99bf556f4daab2da
Autor:
Marina A Afanasyeva, Liudmila V Britanova, Kirill V Korneev, Nikita A Mitkin, Anna A Kuchmiy, Dmitry V Kuprash
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98349 (2014)
Clusterin is a multifunctional protein that participates in tissue remodeling, apoptosis, lipid transport, complement-mediated cell lysis and serves as an extracellular chaperone. The role of clusterin in cancer and neurodegeneration has been extensi
Externí odkaz:
https://doaj.org/article/70e6d2a414c248a6845bf69298348a81
Autor:
Elina A. Zheremyan, Alina S. Ustiugova, Aksinya N. Uvarova, Nina M. Karamushka, Ekaterina M. Stasevich, Violetta S. Gogoleva, Apollinariya V. Bogolyubova, Nikita A. Mitkin, Dmitry V. Kuprash, Kirill V. Korneev
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Regulatory B lymphocytes (Bregs) are B cells with well-pronounced immunosuppressive properties, allowing them to suppress the activity of effector cells. A broad repertoire of immunosuppressive mechanisms makes Bregs an attractive tool for adoptive c
Externí odkaz:
https://doaj.org/article/99464a452b5944f49b072e4a1c6acb6f
Autor:
Alisa M. Gorbacheva, Aksinya N. Uvarova, Alina S. Ustiugova, Arindam Bhattacharyya, Kirill V. Korneev, Dmitry V. Kuprash, Nikita A. Mitkin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Transforming growth factor beta (TGF-β) is the main cytokine responsible for the induction of the epithelial-mesenchymal transition of breast cancer cells, which is a hallmark of tumor transformation to the metastatic phenotype. Recently, r
Externí odkaz:
https://doaj.org/article/3f04f0958de149dda9d153af34e0a963
Autor:
Violetta S. Gogoleva, Dmitry V. Kuprash, Sergei I. Grivennikov, Alexei V. Tumanov, Andrey A. Kruglov, Sergei A. Nedospasov
Publikováno v:
Cells, Vol 11, Iss 12, p 1970 (2022)
TNF and LTα are structurally related cytokines of the TNF superfamily. Their genes are located in close proximity to each other and to the Ltb gene within the TNF/LT locus inside MHC. Unlike Ltb, transcription of Tnf and of Lta is tightly controlled
Externí odkaz:
https://doaj.org/article/b101651ea2a34b4fbae31d6c51a108f6
Autor:
Elina A. Zheremyan, Alina S. Ustiugova, Anastasia I. Radko, Ekaterina M. Stasevich, Aksinya N. Uvarova, Nikita A. Mitkin, Dmitry V. Kuprash, Kirill V. Korneev
Publikováno v:
Biochemistry (Moscow). 88:13-21
Autor:
Yury V. Shebzukhov, Silke Stanislawiak, Taisiya R. Bezhaeva, Sergei A. Nedospasov, Dmitry V. Kuprash
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The Src-family tyrosine kinase Lck is an enzyme associated with the CD4 and CD8 co-receptors and promoting signaling through the T cell receptor (TCR) complex. The levels of Lck expression and activity change during the development and diffe
Externí odkaz:
https://doaj.org/article/1ae3db244fd44027909211aba16d40a4
Autor:
Cécile Gouttefangeas, Hans-Georg Rammensee, Sergei A. Nedospasov, Barbara D. Schmid-Horch, David Eisel, Steffen Walter, Verona Vass, Stefan Stevanović, Pavel V. Belousov, Dmitry N. Penkov, Alexey Y. Sazykin, Ekaterina P. Koroleva, Svetlana V. Khlgatian, Dmitry V. Kuprash, Ludger Grosse-Hovest, Yuriy V. Shebzukhov, Karoline Laske
A mutation in the hydin gene has been recently described as one possible mechanism leading to lethal congenital hydrocephalus in mice, and a similar defect is proposed to be involved in an autosomal recessive form of hydrocephalus in human. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2c82116875e335fbb952f6831e71c9f
https://doi.org/10.1158/2326-6066.c.6548311.v1
https://doi.org/10.1158/2326-6066.c.6548311.v1