Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Dmitry Samarsky"'
Autor:
Jessica T. Lam, Jennifer Lapierre, Anastasia Khvorova, Bernice Smith-Anzures, Tod M. Woolf, Dmitry Samarsky, Karen Bulock, Glenna Ford, Joanne Kamens, William Salomon, James Cardia, William Stanney
Publikováno v:
RNA. 17:1032-1037
RNA interference (RNAi) has been established as an important tool for functional genomics studies and has great promise as a therapeutic intervention for human diseases. In mammalian cells, RNAi is conventionally induced by 19–27-bp RNA duplexes ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0bd0f3b8b502e7197e8ba93f409843
https://doi.org/10.1261/rna.2399411
https://doi.org/10.1261/rna.2399411
Autor:
Merrilyn Datta, Dmitry Samarsky
Publikováno v:
Expert Review of Molecular Diagnostics. 4:11-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2db38c8fb4381f2a010801eaf88bfc2
https://doi.org/10.1586/14737159.4.1.11
https://doi.org/10.1586/14737159.4.1.11
Autor:
Lingfeng Zhao, Xiaoxia Liu, Wei Yang, Zhiyong Qiu, Ping Wu, Qiyi Zeng, Jingjing Zhang, Zhongyi Zhang, Biliang Zhang, Wei Wang, Aimin Ji, Wenqing Zhang, Dmitry Samarsky, Xiaohui Chen, Qian Xu, Xialin Zuo, Guangzu Zhu, Houliang Deng, Zhuomin Wu, Li Liu
Publikováno v:
Nucleic Acids Research
RNAi technology is taking strong position among the key therapeutic modalities, with dozens of siRNA-based programs entering and successfully progressing through clinical stages of drug development. To further explore potentials of RNAi technology as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a51abe9053a2ae76101bd57f80f6982
https://pubmed.ncbi.nlm.nih.gov/25223783
https://pubmed.ncbi.nlm.nih.gov/25223783
Autor:
Robert Cedergren, Edouard Bertrand, Maurille J. Fournier, Dmitry Samarsky, Robert H. Singer, Gerardo Ferbeyre
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6609-6614
A hammerhead ribozyme has been localized to the yeast nucleolus by using the U3 small nucleolar RNA as a carrier. The hybrid small nucleolar RNA:ribozyme, designated a “snorbozyme,” is metabolically stable and cleaves a target U3 RNA with nearly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4661a063a3c5a3666c8cdfba29db0e
https://doi.org/10.1073/pnas.96.12.6609
https://doi.org/10.1073/pnas.96.12.6609
Autor:
Dmitry Samarsky, Maurille J. Fournier
Publikováno v:
Nucleic Acids Research. 27:161-164
Small nucleolar RNAs (snoRNAs) are involved in cleavage of rRNA, modification of rRNA nucleotides and, perhaps, other aspects of ribosome biogenesis in eukaryotic cells. Scores of snoRNAs have been discovered in recent years from various eukaryotes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5859cd2487e2b6be8d51a0941d553e0d
https://doi.org/10.1093/nar/27.1.161
https://doi.org/10.1093/nar/27.1.161
Publikováno v:
Nucleic Acids Research. 24:2059-2066
U14 is a small nucleolar RNA (snoRNA) required for early cleavages of eukaryotic precursor rRNA. The U14 RNA from Saccharomyces cerevisiae is distinguished from its vertebrate homologues by the presence of a stem-loop domain that is essential for fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3862292e8a17d9ca31596be44d3e4ed
https://doi.org/10.1093/nar/24.11.2059
https://doi.org/10.1093/nar/24.11.2059
Autor:
Céline Verheggen, Jean-Marie Blanchard, John Mouaikel, Rémy Bordonné, Edouard Bertrand, Dmitry Samarsky, Denis L. J. Lafontaine
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2002, 21 (11), pp.2736--45. ⟨10.1093/emboj/21.11.2736⟩
EMBO Journal, 2002, 21 (11), pp.2736--45. ⟨10.1093/emboj/21.11.2736⟩
EMBO Journal, EMBO Press, 2002, 21 (11), pp.2736--45. ⟨10.1093/emboj/21.11.2736⟩
EMBO Journal, 2002, 21 (11), pp.2736--45. ⟨10.1093/emboj/21.11.2736⟩
Nucleolar localization of vertebrate box C/D snoRNA involves transit through Cajal bodies, but the significance of this event is unknown. To define better the function of this compartment, we analyzed here the maturation pathway of mammalian U3. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9982c29a4357fcad51242ccbb6d4578
https://europepmc.org/articles/PMC126019/
https://europepmc.org/articles/PMC126019/
The U3 small nucleolar ribonucleoprotein (snoRNP) is composed of a small nucleolar RNA (snoRNA) and at least 10 proteins. The U3 snoRNA base pairs with the pre-rRNA to carry out the A0, A1, and A2 processing reactions that lead to the release of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93eb7e8bf20c1f49030906f4de46a3da
https://europepmc.org/articles/PMC1370138/
https://europepmc.org/articles/PMC1370138/