Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dmitry S. Sheikin"'
Autor:
Dmitry S. Sheikin, Evgeniya S. Titova, Evsey А. Ruchko, Maxim B. Nawrozkij, Anastasiya Kotlyarova, Ivan А. Novakov, Leila L. Brunilina, Tatyana G. Tolstikova, Alla Pavlova, Ivan А. Kirillov, Mariya D. Robinovich
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:769-775
New structural analogs of 3-phenacyluridine were obtained as a result of N(3)-alkylation of 1-(2-acetoxyethyl)- and 1-(2-acetoxyethoxymethyl) uracil. Biological studies of the title compounds in an acute in vivo experiment did not reveal their hypnot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e5ee45cdbddeec9fd54fcb5b6ca7cb
https://doi.org/10.1007/s10593-020-02729-x
https://doi.org/10.1007/s10593-020-02729-x
Autor:
Dmitry S. Sheikin, A. Yu. Maryshev, A. S. Babushkin, Dominique Schols, V. V. Chapurkin, Ivan A. Novakov, M. B. Navrotskii, Evsey A. Ruchko
Publikováno v:
Russian Journal of General Chemistry. 90:352-356
The Tscherniac–Einhorn reaction of 6-methyl and 6-(trifluoromethyl) derivatives of 2-thiouracil with N-(bromomethyl)phthalimide in under basic catalysis leads to the formation of S-amidomethylation products. When using 6-amino-2-thiouracil, decompo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fc8faa527b35aafc0cca4c05f1ae52
https://doi.org/10.1134/s1070363220030056
https://doi.org/10.1134/s1070363220030056
Autor:
Anton Yu. Maryshev, Viktor V. Chapurkin, Dmitry S. Sheikin, Dominique Schols, Yaroslav P. Kuznetsov, Maksim B. Nawrozkij, Ivan A. Novakov, Alexande S. Babushkin, Evsey A. Ruchko, Vadim V. Kachala
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:67-72
The interaction of N-(2-bromoethyl)- and N-(3-bromopropyl)phthalimides with 2-thiouracils substituted at position 6 was studied in alkaline medium, providing S-monoamidoalkylation products and, depending on the substituents, the products of S,O(4)- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70680cd0ce8d00bc8339a6c025bce50
https://doi.org/10.1007/s10593-020-02624-5
https://doi.org/10.1007/s10593-020-02624-5
Autor:
Rossella Fioravanti, Eleonora Proia, Ivan N. Tyurenkov, Denis V. Kurkin, Dmitry A. Bakulin, Nikolay S. Kovalev, Dmitry S. Sheikin, Ivan A. Kirillov, Maxim B. Nawrozkij, Andrey A. Vernigora, Leila L. Brunilina, Francesco Fiorentino, Milan Mladenović, Dante Rotili, Rino Ragno
Publikováno v:
European Journal of Medicinal Chemistry. 245:114902
A series of new pyrimidine thioethers, recognized as the key intermediates in the synthesis of S-DABO antivirals, were prepared and evaluated both in vivo and in silico. The purpose of this evaluation was to find novel structural analogues of the kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cf41bc627bd26476096747ecdf5d0e
https://doi.org/10.1016/j.ejmech.2022.114902
https://doi.org/10.1016/j.ejmech.2022.114902
Autor:
L. L. Brunilina, V. V. Chapurkin, Evsey A. Ruchko, Dmitry S. Sheikin, Dominique Schols, Y. P. Kuznetsov, I. A. Novakov, M. B. Nawrozkij
Publikováno v:
AIP Conference Proceedings.
Synthesis of the novel Isothiobarbamine analogues with lowered basicity has been prepared. The peculiarities of their synthesis and preliminary data on their biological activity are presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3525f32b22ee9567f6113e93580b6b7b
https://doi.org/10.1063/5.0018050
https://doi.org/10.1063/5.0018050