Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Dmitry S. Karpov"'
Autor:
Dmitry S. Karpov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5292 (2024)
Harnessing of CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated genes) systems for detection, chemical modification, and sequence editing of nucleic acids dramatically changed many fields of fundamental science,
Externí odkaz:
https://doaj.org/article/bc6cd21ab2db4ea697895730e27ddfe3
Autor:
Kirill A. Kulagin, Elizaveta S. Starodubova, Pamila J. Osipova, Anastasia V. Lipatova, Igor A. Cherdantsev, Svetlana V. Poddubko, Vadim L. Karpov, Dmitry S. Karpov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3977 (2024)
Proteasome inhibitors are used in the therapy of several cancers, and clinical trials are underway for their use in the treatment of glioblastoma (GBM). However, GBM becomes resistant to chemotherapy relatively rapidly. Recently, the overexpression o
Externí odkaz:
https://doaj.org/article/3660cfcaf8dd44ea97beab5c1ee9a7da
Autor:
Natalya S. Gladysh, Alina S. Bogdanova, Maxim A. Kovalev, George S. Krasnov, Vsevolod V. Volodin, Anastasia I. Shuvalova, Nikita V. Ivanov, Mikhail I. Popchenko, Aleksandra D. Samoilova, Aleksandra N. Polyakova, Alexey A. Dmitriev, Nataliya V. Melnikova, Dmitry S. Karpov, Nadezhda L. Bolsheva, Maria S. Fedorova, Anna V. Kudryavtseva
Publikováno v:
Biology, Vol 12, Iss 12, p 1519 (2023)
The white poplar (Populus alba L.) has good potential for a green economy and phytoremediation. Bioaugmentation using endophytic bacteria can be considered as a safe strategy to increase poplar productivity and its resistance to toxic urban condition
Externí odkaz:
https://doaj.org/article/ceb49c568fa44a8d8b938a98fc0edfd9
Autor:
Dmitry S. Karpov, Anastasiia O. Sosnovtseva, Svetlana V. Pylina, Asya N. Bastrich, Darya A. Petrova, Maxim A. Kovalev, Anastasija I. Shuvalova, Anna K. Eremkina, Natalia G. Mokrysheva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17320 (2023)
Type 1 diabetes mellitus (T1D) is an autoimmune disease caused by the destruction of insulin-producing β-cells in the pancreas by cytotoxic T-cells. To date, there are no drugs that can prevent the development of T1D. Insulin replacement therapy is
Externí odkaz:
https://doaj.org/article/7bf15955c004472190592c4a47af3b70
Autor:
Artem I. Davletshin, Anna A. Matveeva, Stanislav S. Bachurin, Dmitry S. Karpov, David G. Garbuz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 444 (2023)
CRISPR/Cas systems are used for genome editing, both in basic science and in biotechnology. However, CRISPR/Cas editors have several limitations, including insufficient specificity leading to “off-targets” and the dependence of activity on chroma
Externí odkaz:
https://doaj.org/article/3c71e679c4614d50a55d0e74cccea1e4
Autor:
Dmitrii A. Abashkin, Dmitry S. Karpov, Artemii O. Kurishev, Ekaterina V. Marilovtseva, Vera E. Golimbet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15746 (2023)
Schizophrenia (SZ) is a common psychiatric neurodevelopmental disorder with a complex genetic architecture. Genome-wide association studies indicate the involvement of several transcription factors, including ASCL1, in the pathogenesis of SZ. We aime
Externí odkaz:
https://doaj.org/article/9eeb74e3a3c04ca19106b76553f59e8f
Autor:
Daria S. Spasskaya, Kirill A. Kulagin, Evgenia N. Grineva, Pamila J. Osipova, Svetlana V. Poddubko, Julia A. Bubis, Elizaveta M. Kazakova, Tomiris T. Kusainova, Vladimir A. Gorshkov, Frank Kjeldsen, Vadim L. Karpov, Irina A. Tarasova, Dmitry S. Karpov
Publikováno v:
Journal of Fungi, Vol 9, Iss 3, p 351 (2023)
Various external and internal factors damaging DNA constantly disrupt the stability of the genome. Cells use numerous dedicated DNA repair systems to detect damage and restore genomic integrity in a timely manner. Ribonucleotide reductase (RNR) is a
Externí odkaz:
https://doaj.org/article/1f72b77b8ce941f2bf18f6e03c2c68ae
Autor:
Artemiy O. Kurishev, Dmitry S. Karpov, Nonna I. Nadolinskaia, Anna V. Goncharenko, Vera E. Golimbet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 241 (2022)
The study of diseases of the central nervous system (CNS) at the molecular level is challenging because of the complexity of neural circuits and the huge number of specialized cell types. Moreover, genomic association studies have revealed the comple
Externí odkaz:
https://doaj.org/article/3f0908fd492d439a8c6f5d42de6acd52
Autor:
Dmitry S. Karpov, Natalia A. Demidova, Kirill A. Kulagin, Anastasija I. Shuvalova, Maxim A. Kovalev, Ruslan A. Simonov, Vadim L. Karpov, Anastasiya V. Snezhkina, Anna V. Kudryavtseva, Regina R. Klimova, Alla A. Kushch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14847 (2022)
Almost all people become infected with herpes viruses, including herpes simplex virus type 1 (HSV-1), during their lifetime. Typically, these viruses persist in a latent form that is resistant to all available antiviral medications. Under certain con
Externí odkaz:
https://doaj.org/article/093c17736d1a4ab59cd69eb592de2ca1
Autor:
Mervi T. Hyvönen, Olga A. Smirnova, Vladimir A. Mitkevich, Vera L. Tunitskaya, Maxim Khomutov, Dmitry S. Karpov, Sergey P. Korolev, Merja R. Häkkinen, Marko Pietilä, Marina B. Gottikh, Jouko Vepsäläinen, Leena Alhonen, Alexander A. Makarov, Sergey N. Kochetkov, Heather M. Wallace, Tuomo A. Keinänen, Alex R. Khomutov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4614 (2022)
The polyamines, spermine (Spm) and spermidine (Spd), are important for cell growth and function. Their homeostasis is strictly controlled, and a key downregulator of the polyamine pool is the polyamine-inducible protein, antizyme 1 (OAZ1). OAZ1 inhib
Externí odkaz:
https://doaj.org/article/0c564f8e408144a997efe0c60a190534