Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dmitry S. Granat"'
Autor:
Andrey V. Bogolubsky, Pavel K. Mykhailiuk, Sergey E. Pipko, Roman Doroschuk, Dmitry S. Granat, Yurii S. Moroz, Anzhelika I. Konovets, Andrey A. Tolmachev
Publikováno v:
ACS Combinatorial Science. 16:303-308
One-pot parallel synthesis of unsymmetrical aliphatic ureas was achieved with bis(2,2,2-trifluoroethyl) carbonate. The procedure worked well for both the monosubstituted and functionalized alkyl amines and required no special conditions (temperature
Autor:
Alexander Shivanyuk, Dmitriy M. Volochnyuk, Dmitry S. Granat, Sergey V. Ryabukhin, Andrey S. Plaskon
Publikováno v:
Synlett. 24:2675-2678
Twenty-five diverse pyrazolo[3,4- d ]-4,5-dihydropyrimidines were synthesized in 73–91% yield through TMS-promoted [5+1] heterocyclization of aldehydes with pyrazolylamidines.
Autor:
Alexander Shivanyuk, Dmitry S. Granat, Andrey S. Plaskon, Sergey V. Ryabukhin, Andrey A. Tolmachev, Yulian M. Volovenko
Publikováno v:
ACS Combinatorial Science. 14:465-470
Thirteen 5-hetarylaminopyrazoles were synthesized in 62-93% yield through the arylation of 1-isopropyl- and 1-phenyl-5-aminopyrazoles with electrophilic hetarylhalides under optimized conditions. Condensation of 5-hetarylaminopyrazoles with carbonyl
Autor:
Andrey A. Tolmachev, Pavel V. Khodakovskiy, Sergey V. Ryabukhin, Alexander N. Shivanyuk, Dmitry S. Granat
Publikováno v:
Tetrahedron Letters. 49:3997-4002
New efficient one-pot methodology for the preparative synthesis of β-imidazolylpropionamides was elaborated. It is based on the addition of imidazole to the activated double bond of the intermediate acrylimidazolide in the reaction between diverse a
Publikováno v:
ChemInform. 45
A small library of hitherto unprepared pyrazolo[3,4-d]-4,5-dihydropyrimidin-6-ones was synthesized on a preparative scale. The synthesis starts with a substituted 5-aminopyrazole that reacts with an isocyanate to give the corresponding urea. The latt
Autor:
Dmitry S. Granat, Sergey V. Ryabukhin, Dmitriy M. Volochnyuk, Andrey S. Plaskon, Alexander Shivanyuk
Publikováno v:
ChemInform. 45
More than twenty pyrazolodihydropyrimidine derivatives are prepared through condensation of secondary amidines with aromatic aldehydes in the presence of TmsCl as activator for the CO-group and water scavenger.
Autor:
Oleksandr O. Grygorenko, Eugeniy N. Ostapchuk, Dmitry S. Granat, Dmitriy M. Panov, Sergey V. Ryabukhin, Dmitriy V. Kryvoruchko
Publikováno v:
ACS combinatorial science. 16(3)
One-pot variation of Castagnoli condensation, that is, reaction of cyclic anhydrides, amines, and aldehydes, has been developed as a combinatorial approach to 1,2-disubstituted 5-oxopyrrolidine- and 6-oxopiperidine-3-carboxylic acids, as well as thei
Publikováno v:
Tetrahedron Letters. 55:1846-1847
A small library of hitherto unprepared pyrazolo[3,4-d]-4,5-dihydropyrimidin-6-ones was synthesized on a preparative scale. The synthesis starts with a substituted 5-aminopyrazole that reacts with an isocyanate to give the corresponding urea. The latt
Autor:
Andrey A. Tolmachev, Sergey V. Ryabukhin, Pavel V. Khodakovskiy, Dmitry S. Granat, Alexander N. Shivanyuk
Publikováno v:
ChemInform. 39
New efficient one-pot methodology for the preparative synthesis of β-imidazolylpropionamides was elaborated. It is based on the addition of imidazole to the activated double bond of the intermediate acrylimidazolide in the reaction between diverse a
Autor:
Halyna Kuznietsova, Taras Diachuk, Iryna Pishel, Rustam T. Iminov, Pavel K. Mykhailiuk, Dmitry S. Granat, Andrei A. Tolmachev, Petro Borysko, Kostiantyn Shvydenko, Vladyslav Vilchynskyi, Kateryna Fominova, Anastasiia S. Kuznetsova, Eduard Litskan, Taras Savchuk, Yurii V. Dmytriv, Andrii V. Bolbut, Daniil Vysochyn, Ruslan I. Vaskevych, Valentyn R. Badlo, Alla I. Vaskevych, Vasyl Ripenko, Oleksiy Svitlychnyi, Olexandra Pavlova, Vadym V. Levterov, Volodymyr V. Semeno, Vladyslav Meliantsev, Igor Kovalchuk
Publikováno v:
Chemical Science
A general approach to a new generation of spirocyclic molecules – oxa-spirocycles – was developed. The key synthetic step was iodocyclization. More than 150 oxa-spirocyclic compounds were prepared. Incorporation of an oxygen atom into the spirocy