Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dmitry Pichugin"'
Autor:
Libin Ye, Chris Neale, Adnan Sljoka, Brent Lyda, Dmitry Pichugin, Nobuyuki Tsuchimura, Sacha T. Larda, Régis Pomès, Angel E. García, Oliver P. Ernst, Roger K. Sunahara, R. Scott Prosser
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
G protein-coupled receptors (GPCRs) are membrane receptors and are important drug targets, whose regulation by cations is poorly understood. Here authors use NMR to elucidate effects of cations on functional states of the GPCR, adenosine A2Areceptor
Externí odkaz:
https://doaj.org/article/25e0679825f24b93877531f883a95c68
Autor:
Mitchell A. Winnik, Gregory Molev, Ian Manners, Paul A. Rupar, Menandro Cruz, Gerald Guerin, Dmitry Pichugin, Fei Qi
Publikováno v:
Macromolecules. 52:208-216
We report a study of the dissolution of core-crystalline polyferrocenyldimethylsilane-block-polyisoprene (PFS53-b-PI637, where the subscripts are the degrees of polymerization of the two blocks) micelle fragments in decane for different concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae1cba3e4021256332d4c0d0ec806fc0
https://doi.org/10.1021/acs.macromol.8b02126
https://doi.org/10.1021/acs.macromol.8b02126
Publikováno v:
The Journal of Biological Chemistry
Nickel is essential for the survival of the pathogenic bacteria Helicobacter pylori in the fluctuating pH of the human stomach. Due to its inherent toxicity and limited availability, nickel homeostasis is maintained through a network of pathways that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6564cd1b9f4682991067e1c1cd6026b
https://pubmed.ncbi.nlm.nih.gov/33199369
https://pubmed.ncbi.nlm.nih.gov/33199369
Publikováno v:
Yu, Q, Pichugin, D, Cruz, M, Guerin, G, Manners, I & Winnik, M A 2018, ' NMR Study of the Dissolution of Core-Crystalline Micelles ', Macromolecules, vol. 51, no. 9, pp. 3279-3289 . https://doi.org/10.1021/acs.macromol.8b00098
Short fragments of the core-crystalline micelles formed by a sample of poly(ferrocenyldimethylsilane)-block-poly(isoprene) (PFS-b-PI) block copolymer (BCP) underwent self-seeding in decane when heated above its dissolution temperature. Variable tempe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e772726ed7425b9517524e0bf2d6e834
https://doi.org/10.1021/acs.macromol.8b00098
https://doi.org/10.1021/acs.macromol.8b00098
Publikováno v:
J Biol Chem
A hallmark of G-protein–coupled receptors (GPCRs) is the conversion of external stimuli into specific cellular responses. In this tightly-regulated process, extracellular ligand binding by GPCRs promotes specific conformational changes within the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89076221ae75807b04e4b531d8071840
https://pubmed.ncbi.nlm.nih.gov/31362983
https://pubmed.ncbi.nlm.nih.gov/31362983
Publikováno v:
Bioconjugate Chemistry. 26:2376-2383
Indoles and indole-derivatives can be used to site-specifically label proteins on lysine and N-terminal amino groups under mild, nondenaturing reaction conditions. Hen egg white lysozyme (HEWL) and α-lactalbumin were labeled with indole, fluoroindol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7710f423d597062be872d8468f5095cb
https://doi.org/10.1021/acs.bioconjchem.5b00457
https://doi.org/10.1021/acs.bioconjchem.5b00457
Autor:
Adnan Sljoka, Régis Pomès, Chris Neale, Dmitry Pichugin, Scott Prosser, Libin Ye, Sacha Thierry Larda, Nobuyuki Tsuchimura, Oliver P. Ernst, Angel E. Garcia, Roger K. Sunahara, Brent R. Lyda
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature communications, vol 9, iss 1
Nature communications, vol 9, iss 1
Cations play key roles in regulating G-protein-coupled receptors (GPCRs), although their mechanisms are poorly understood. Here, 19F NMR is used to delineate the effects of cations on functional states of the adenosine A2A GPCR. While Na+ reinforces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04985a17d490fa15d18c9d111f2c57ee
https://doi.org/10.1038/s41467-018-03314-9
https://doi.org/10.1038/s41467-018-03314-9
Autor:
Libin, Ye, Chris, Neale, Adnan, Sljoka, Brent, Lyda, Dmitry, Pichugin, Nobuyuki, Tsuchimura, Sacha T, Larda, Régis, Pomès, Angel E, García, Oliver P, Ernst, Roger K, Sunahara, R Scott, Prosser
Publikováno v:
Nature Communications
Cations play key roles in regulating G-protein-coupled receptors (GPCRs), although their mechanisms are poorly understood. Here, 19F NMR is used to delineate the effects of cations on functional states of the adenosine A2A GPCR. While Na+ reinforces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9019286364f425d6a50c6c6a2cae69dc
https://pubmed.ncbi.nlm.nih.gov/29636462
https://pubmed.ncbi.nlm.nih.gov/29636462
Publikováno v:
Topics in Catalysis. 56:1199-1207
Using our transfer hydrogenation (TH) pre-catalyst trans-(R,R)-[Fe(NCMe)CO(PPh2C6H4CH=NCHPh-)2][BF4]2 (1) we investigated the reverse reaction, oxidative kinetic resolution, and were able to achieve turn-over frequencies up to 335 h−1 and s-values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8637a260d35125ce03411c80a571e75
https://doi.org/10.1007/s11244-013-0086-2
https://doi.org/10.1007/s11244-013-0086-2
Autor:
Yijie Lu, Dmitry Pichugin, Mitchell A. Winnik, Mohsen Soleimani, Sepehr Mastour Tehrani, Gerald Guerin
Publikováno v:
Biomacromolecules. 16(10)
Immobilization of enzymes on solid supports has been widely used to improve enzyme recycling, enzyme stability, and performance. We are interested in using aqueous microgels (colloidal hydrogels) as carriers for enzymes used in high-temperature react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5982227354ed6af7406fb089005f83f6
https://pubmed.ncbi.nlm.nih.gov/26335392
https://pubmed.ncbi.nlm.nih.gov/26335392