Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dmitry N. Pelageev"'
Publikováno v:
Marine Drugs, Vol 21, Iss 7, p 407 (2023)
This review provides information on the synthesis and revision of the structures of natural dimeric (poly)hydroxynaphthazarins, metabolites of echinoderms and lichens, and on the refinement of the direction and mechanism of reactions in the synthesis
Externí odkaz:
https://doaj.org/article/306ed612b148476a84aac9786bb8e19b
New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide
Autor:
Sergey A. Dyshlovoy, Olesya I. Zhuravleva, Jessica Hauschild, Tobias Busenbender, Dmitry N. Pelageev, Anton N. Yurchenko, Yuliya V. Khudyakova, Alexandr S. Antonov, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg
Publikováno v:
Marine Drugs, Vol 21, Iss 1, p 54 (2023)
Marine fungi serve as a valuable source for new bioactive molecules bearing various biological activities. In this study, we report on the isolation of a new indole diketopiperazine alkaloid deoxy-14,15-dehydroisoaustamide (1) from the marine-derived
Externí odkaz:
https://doaj.org/article/045b1ac7fd144b5f833a4e57488d6c26
Autor:
Olesya I. Zhuravleva, Galina K. Oleinikova, Alexandr S. Antonov, Natalia N. Kirichuk, Dmitry N. Pelageev, Anton B. Rasin, Alexander S. Menshov, Roman S. Popov, Natalya Yu. Kim, Ekaterina A. Chingizova, Artur R. Chingizov, Olga O. Volchkova, Gunhild von Amsberg, Sergey A. Dyshlovoy, Ekaterina A. Yurchenko, Irina V. Guzhova, Anton N. Yurchenko
Publikováno v:
Journal of Fungi, Vol 8, Iss 5, p 454 (2022)
Six new polyketides acrucipentyns A–F (1–6) were isolated from the alga-derived fungus Asteromyces cruciatus KMM 4696. Their structures were established based on spectroscopic methods. The absolute configurations of acrucipentyn A was assigned by
Externí odkaz:
https://doaj.org/article/4f21d8ab0d8640a7a0c37917f647552d
Autor:
Sergey A. Dyshlovoy, Dmitry N. Pelageev, Lea S. Jakob, Ksenia L. Borisova, Jessica Hauschild, Tobias Busenbender, Moritz Kaune, Ekaterina A. Khmelevskaya, Markus Graefen, Carsten Bokemeyer, Victor Ph. Anufriev, Gunhild von Amsberg
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 949 (2021)
Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here, we report the synthesis of new hybrid molecules consisting of 2-chloroethylthio and 1,4-nap
Externí odkaz:
https://doaj.org/article/72851b83bf614af68fb86216a3d6a4f8
Autor:
Sergey A. Dyshlovoy, Dmitry N. Pelageev, Jessica Hauschild, Yurii E. Sabutskii, Ekaterina A. Khmelevskaya, Christoph Krisp, Moritz Kaune, Simone Venz, Ksenia L. Borisova, Tobias Busenbender, Vladimir A. Denisenko, Hartmut Schlüter, Carsten Bokemeyer, Markus Graefen, Sergey G. Polonik, Victor Ph. Anufriev, Gunhild von Amsberg
Publikováno v:
Marine Drugs, Vol 18, Iss 5, p 251 (2020)
The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in aerobic conditions. Targeting the Warburg effect to specifically deliver
Externí odkaz:
https://doaj.org/article/171eebda0cf448cc81b3cc2c80b450ab
Autor:
Dmitry N. Pelageev, Ksenia L. Borisova, Svetlana M. Kovach, Vyacheslav V. Makhankov, Victor Ph. Anufriev
Publikováno v:
Mendeleev Communications. 33:231-233
Autor:
Dmitry N. Pelageev, Victor Ph. Anufriev, Sergey G. Polonik, Sergey A. Dyshlovoy, Vladimir A. Denisenko, Christoph Krisp, Jessica Hauschild, Hartmut Schlüter, Ekaterina A. Khmelevskaya, Markus Graefen, Ksenia L. Borisova, Gunhild von Amsberg, Carsten Bokemeyer, Simone Venz, Moritz Kaune, Tobias Busenbender, Yurii E Sabutskii
Publikováno v:
Marine Drugs
Volume 18
Issue 5
Marine Drugs, Vol 18, Iss 251, p 251 (2020)
Volume 18
Issue 5
Marine Drugs, Vol 18, Iss 251, p 251 (2020)
The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in aerobic conditions. Targeting the Warburg effect to specifically deliver
Publikováno v:
Synthesis. 50:3931-3935
A three-step procedure for the synthesis of 1H-benzo[b]xanthene-6,11,12-trione derivatives is described. The procedure involves the halogenation of 12-(3-hydroxy-1,4-naphthoquinon-2-yl)-6H-benzo[b]xanthene-6,11-(12H)-diones, followed by treatment wit
Publikováno v:
Tetrahedron Letters. 60:1022-1024
A total synthesis of dioncoquinone B and related compounds, including ancistroquinones B, C and malvon A, is presented. The strategy is based on available reagents and can be used as a preparative synthesis of a number of natural and synthetic biolog
Autor:
Dmitry N. Pelageev, Yuri Sabutski, Dmitry L. Aminin, Ekaterina S. Menchinskaya, Sergei G Polonik, Ekaterina A. Chingizova, Evgeny A. Pislyagin, Galina N. Likhatskaya
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9933, p 9933 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9933, p 9933 (2021)
Targeted screening using the MTT cell viability test with a mini-library of natural and synthetic 1,4-naphthoquinones and their derivatives was performed in order to increase the survival of Neuro-2a neuroblastoma cells in in vitro paraquat and 6-hyd