Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Dmitry Kobak"'
Autor:
Shan Shen, Xiaolong Jiang, Federico Scala, Jiakun Fu, Paul Fahey, Dmitry Kobak, Zhenghuan Tan, Na Zhou, Jacob Reimer, Fabian Sinz, Andreas S. Tolias
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Cortical activity is modulated by an intricate network of feedforward and feedback connectivity. Here the authors demonstrate distinct organizational rules govern feedback projections from lateral medial area to V1 versus projections from vibrissal M
Externí odkaz:
https://doaj.org/article/dc19ad500a054988abdc41142138b075
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background Standard preprocessing of single-cell RNA-seq UMI data includes normalization by sequencing depth to remove this technical variability, and nonlinear transformation to stabilize the variance across genes with different expression
Externí odkaz:
https://doaj.org/article/b0c1779c0b134cc88809ae17e2c25707
Autor:
Ariel Karlinsky, Dmitry Kobak
Publikováno v:
eLife, Vol 10 (2021)
Comparing the impact of the COVID-19 pandemic between countries or across time is difficult because the reported numbers of cases and deaths can be strongly affected by testing capacity and reporting policy. Excess mortality, defined as the increase
Externí odkaz:
https://doaj.org/article/177b64d8d19043a7b3be2c6872b32748
Autor:
Dmitry Kobak, Philipp Berens
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of
Externí odkaz:
https://doaj.org/article/b26f011209eb4d4294d5ab8dd1fde844
Autor:
Federico Scala, Dmitry Kobak, Shen Shan, Yves Bernaerts, Sophie Laturnus, Cathryn Rene Cadwell, Leonard Hartmanis, Emmanouil Froudarakis, Jesus Ramon Castro, Zheng Huan Tan, Stelios Papadopoulos, Saumil Surendra Patel, Rickard Sandberg, Philipp Berens, Xiaolong Jiang, Andreas Savas Tolias
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Layer 4 of the mammalian neocortex is important for cortical information processing but its cellular composition and local circuits remains elusive. The authors compared two primary sensory cortical areas of mice and found differences in cell composi
Externí odkaz:
https://doaj.org/article/612a91e14d9e463bb0023b10e7cbb11e
Autor:
Cathryn R Cadwell, Federico Scala, Paul G Fahey, Dmitry Kobak, Shalaka Mulherkar, Fabian H Sinz, Stelios Papadopoulos, Zheng H Tan, Per Johnsson, Leonard Hartmanis, Shuang Li, Ronald J Cotton, Kimberley F Tolias, Rickard Sandberg, Philipp Berens, Xiaolong Jiang, Andreas Savas Tolias
Publikováno v:
eLife, Vol 9 (2020)
Clones of excitatory neurons derived from a common progenitor have been proposed to serve as elementary information processing modules in the neocortex. To characterize the cell types and circuit diagram of clonally related excitatory neurons, we per
Externí odkaz:
https://doaj.org/article/b450fceab0a24c2a90e791d387e2e096
Publikováno v:
eLife, Vol 8 (2019)
The accuracy of the neural code depends on the relative embedding of signal and noise in the activity of neural populations. Despite a wealth of theoretical work on population codes, there are few empirical characterizations of the high-dimensional s
Externí odkaz:
https://doaj.org/article/d4513e583d6148e0a300f22cc8b2c788
Autor:
Federico Scala, Dmitry Kobak, Shen Shan, Yves Bernaerts, Sophie Laturnus, Cathryn Rene Cadwell, Leonard Hartmanis, Emmanouil Froudarakis, Jesus Ramon Castro, Zheng Huan Tan, Stelios Papadopoulos, Saumil Surendra Patel, Rickard Sandberg, Philipp Berens, Xiaolong Jiang, Andreas Savas Tolias
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/0882466ba535491b8d5077470619a5fe
Autor:
Dmitry Kobak, Wieland Brendel, Christos Constantinidis, Claudia E Feierstein, Adam Kepecs, Zachary F Mainen, Xue-Lian Qi, Ranulfo Romo, Naoshige Uchida, Christian K Machens
Publikováno v:
eLife, Vol 5 (2016)
Neurons in higher cortical areas, such as the prefrontal cortex, are often tuned to a variety of sensory and motor variables, and are therefore said to display mixed selectivity. This complexity of single neuron responses can obscure what information
Externí odkaz:
https://doaj.org/article/da5c664057064fb29530937ac13fe0a9
The number of publications in biomedicine and life sciences has rapidly grown over the last decades, with over 1.5 million papers now being published every year. This makes it difficult to keep track of new scientific works and to have an overview of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e266dd6e124168a9f9cfc2087d277217
https://doi.org/10.1101/2023.04.10.536208
https://doi.org/10.1101/2023.04.10.536208