Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dmitry Kazansky"'
Autor:
Anastasiia Kalinina, Nadezda Persiyantseva, Olga Britanova, Ksenia Lupyr, Irina Shagina, Ludmila Khromykh, Dmitry Kazansky
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3196-3209 (2023)
T cell engineering with T cell receptors (TCR) specific to tumor antigens has become a breakthrough towards personalized cancer adoptive cell immunotherapy. However, the search for therapeutic TCRs is often challenging, and effective strategies are s
Externí odkaz:
https://doaj.org/article/34896930424348b88c1bbd6fca7a0fae
Autor:
Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112480- (2022)
Adoptive cell therapy (ACT) based on TCR- or CAR-T cells has become an efficient immunotherapeutic approach for the treatment of various diseases, including cancer. Previously, we developed a novel strategy for generating therapeutic T cell products
Externí odkaz:
https://doaj.org/article/9a07af43c47d43499f688336181fc705
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100368- (2021)
Summary: Adoptive transfer therapy has great potential to treat diseases such as cancer as well as autoimmune and infectious diseases. Identification of chain-centric T cell receptors (TCRs) with the dominant-active antigen-specific α-chains (TCRα)
Externí odkaz:
https://doaj.org/article/444e9448435f424096cc13228dd270b5
Autor:
Khromykh, Anastasiia Kalinina, Maria Semenova, Alexandra Bruter, Ekaterina Varlamova, Marina Kubekina, Natalia Pavlenko, Yulia Silaeva, Alexey Deikin, Elena Antoshina, Tatyana Gorkova, Lubov Trukhanova, Alla Salmina, Svetlana Novikova, Dmitry Voronkov, Dmitry Kazansky, Ludmila
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11279
The precise balance of Th1, Th2, and Th17 cytokines is a key factor in successful pregnancy and normal embryonic development. However, to date, not all humoral factors that regulate and influence physiological pregnancy have been completely studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::b9e8c9d413573f85993fa319981fedac
Autor:
Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss, Pp 112480-(2022)
Adoptive cell therapy (ACT) based on TCR- or CAR-T cells has become an efficient immunotherapeutic approach for the treatment of various diseases, including cancer. Previously, we developed a novel strategy for generating therapeutic T cell products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9083cb146d2ef232e11a05270b8c8c
https://pubmed.ncbi.nlm.nih.gov/34915667
https://pubmed.ncbi.nlm.nih.gov/34915667
Autor:
Maria, Zamkova, Anastasiya, Kalinina, Yuliya, Silaeva, Nadezhda, Persiyantseva, Alexandra, Bruter, Alexey, Deikin, Ludmila, Khromykh, Dmitry, Kazansky
Publikováno v:
Oncotarget
Both TCRα and TCRβ types of T-cell receptors contribute to antigen recognition. However, some TCRs have chain centricity, which means that either the α-chain or the β-chain dictates the peptide–MHC complex specificity. Most earlier reports inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f581049c26b536792db9c5ef6c5cf08
https://pubmed.ncbi.nlm.nih.gov/31448049
https://pubmed.ncbi.nlm.nih.gov/31448049
Autor:
Dmitry Kazansky, Yulia Silaeva, Anastasia Kalinina, Murad Vagida, Ludmila Khromykh, Alexei Deikin, Tatiana Ermolkevich, Elena Sadchikova, Igor Goldman
Publikováno v:
The Journal of Immunology. 190:117.21-117.21
To investigate impact of TCR transgenic chains in formation of activation surface phenotype of T lymphocytes, we have generated mouse strain expressing transgenic beta-chain of TCR 1D1 (belonging to Vbeta6 family) on genetical background B10.D2(R101)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c8aac3b4c3ef148988481999fe635c
https://doi.org/10.4049/jimmunol.190.supp.117.21
https://doi.org/10.4049/jimmunol.190.supp.117.21
Publikováno v:
The Journal of Immunology. 186:46.11-46.11
It is known that central memory cells CD8+ are found in immunocompetent lymphoid organs, such as spleen and lymph nodes. Previously, we described the approach allowing to see and estimate selective proliferation of memory cells in MLR with heat-silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24a1b436391689e05baf0cc36e2714b2
https://doi.org/10.4049/jimmunol.186.supp.46.11
https://doi.org/10.4049/jimmunol.186.supp.46.11