Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dmitry Karachentsev"'
Autor:
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser, Maria Luisa Franco, Burcu Özcan, Diana Gomes Moreira, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Oksana Berezovska, William Mobley, Lucía Chávez-Gutiérrez
Publikováno v:
eLife, Vol 12 (2024)
Amyloid β (Aβ) peptides accumulating in the brain are proposed to trigger Alzheimer’s disease (AD). However, molecular cascades underlying their toxicity are poorly defined. Here, we explored a novel hypothesis for Aβ42 toxicity that arises from
Externí odkaz:
https://doaj.org/article/2631ca395939430b962c9f2eb0249faf
Autor:
Xu‐Qiao Chen, Mariko Sawa, Ann Becker, Dmitry Karachentsev, Xinxin Zuo, Kevin D. Rynearson, Rudolph E. Tanzi, William C. Mobley
Publikováno v:
Annals of Neurology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab8e60150a14035aa44f91526cda89af
https://doi.org/10.1002/ana.26659
https://doi.org/10.1002/ana.26659
Autor:
Amalia, Capilla, Dmitry, Karachentsev, Rachel A, Patterson, Anita, Hermann, Michelle T, Juarez, William, McGinnis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(13)
After breaks in animal epidermal barriers, repair genes are activated in the cells adjacent to wound sites that help regenerate the barrier. The fruit fly Drosophila melanogaster is a favorable genetic system to find molecular detection systems that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86a6e6644462a217aea4e8f0f60d4ae9
https://pubmed.ncbi.nlm.nih.gov/28289197
https://pubmed.ncbi.nlm.nih.gov/28289197
Publikováno v:
Genetics. 179:317-322
Di- and trimethylation of histone H4 lysine20 (H4K20) are thought to play an important role in controlling gene expression in vertebrates and in Drosophila. By inducing a null mutation in Drosophila Suv4-20, we show that it encodes the histone H4 lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed326405e025e35084cd03172d852596
https://doi.org/10.1534/genetics.108.087650
https://doi.org/10.1534/genetics.108.087650
Methylation of specific amino acids in histone tails is responsible for packaging DNA into condensed, repressed chromatin, and into open chromatin that is accessible to the transcription machinery. Monomethylation and trimethylation of histone H4-lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d525c891258cec2c00df385b7e872bea
https://europepmc.org/articles/PMC1945120/
https://europepmc.org/articles/PMC1945120/
Publikováno v:
Genesdevelopment. 19(4)
The histone methyl transferase PR-Set7 mediates histone H4 Lys 20 methylation, a mark of constitutive and facultative heterochromatin. We isolated a null mutation in Drosophila PR-Set7 that suppresses position effect variegation, indicating that PR-S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e544661fe21083d1fad7afbe4efe2d93
https://pubmed.ncbi.nlm.nih.gov/15681608
https://pubmed.ncbi.nlm.nih.gov/15681608