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pro vyhledávání: '"Dmitry Kamashev"'
Autor:
Dmitry Kamashev, Nina Shaban, Galina Zakharova, Alexander Modestov, Мargarita Kamynina, Sergey Baranov, Anton Buzdin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Dual inhibitors of HER2 and EGFR, such as lapatinib, have shown significant efficacy for the therapy of HER2-positive breast cancer. Previous experiments showed that in cell cultures, the efficacy of lapatinib was significantly reduced by exposure to
Externí odkaz:
https://doaj.org/article/3e14a79eb1d44eacb3f92765d89704fa
Autor:
Maxim Sorokin, Alexander Gorelyshev, Victor Efimov, Evgenia Zotova, Marianna Zolotovskaia, Elizaveta Rabushko, Denis Kuzmin, Alexander Seryakov, Dmitry Kamashev, Xinmin Li, Elena Poddubskaya, Maria Suntsova, Anton Buzdin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor mutation burden (TMB) is a well-known efficacy predictor for checkpoint inhibitor immunotherapies. Currently, TMB assessment relies on DNA sequencing data. Gene expression profiling by RNA sequencing (RNAseq) is another type of analysis that ca
Externí odkaz:
https://doaj.org/article/3accc6fa25814229934dc84dbeba498f
Autor:
Dmitry Kamashev, Maksim Sorokin, Irina Kochergina, Aleksey Drobyshev, Uliana Vladimirova, Marianna Zolotovskaia, Igor Vorotnikov, Nina Shaban, Mikhail Raevskiy, Denis Kuzmin, Anton Buzdin
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06394- (2021)
Many patients fail to respond to EGFR-targeted therapeutics, and personalized diagnostics is needed to identify putative responders. We investigated 1630 colorectal and lung squamous carcinomas and 1357 normal lung and colon samples and observed huge
Externí odkaz:
https://doaj.org/article/9d100a741e0e405fad1b69f335f7585a
Autor:
Uliana Vladimirova, Anton Buzdin, Igor Vorotnikov, Maksim Sorokin, Mikhail Raevskiy, Denis Kuzmin, Aleksey Drobyshev, Dmitry Kamashev, Nina Shaban, Marianna Zolotovskaia, Irina Kochergina
Publikováno v:
Heliyon
Heliyon, Vol 7, Iss 3, Pp e06394-(2021)
Heliyon, Vol 7, Iss 3, Pp e06394-(2021)
Many patients fail to respond to EGFR-targeted therapeutics, and personalized diagnostics is needed to identify putative responders. We investigated 1630 colorectal and lung squamous carcinomas and 1357 normal lung and colon samples and observed huge
Autor:
Mikhail Raevskiy, Maxim Sorokin, Galina Zakharova, Victor Tkachev, Nicolas Borisov, Denis Kuzmin, Kristina Kremenchutckaya, Alexander Gudkov, Dmitry Kamashev, Anton Buzdin
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2611
Previously, we have shown that the aggregation of RNA-level gene expression profiles into quantitative molecular pathway activation metrics results in lesser batch effects and better agreement between different experimental platforms. Here, we invest
Autor:
M.A. Gorbacheva, A.V. Lipkin, K.M. Boyko, D.A. Korzhenevskiy, Dmitry Kamashev, Vladimir Popov, Anna Vanyushkina, Tatiana V. Rakitina
Publikováno v:
Acta crystallographica. Section F, Structural biology communications. 71(Pt 1)
HU proteins belong to the nucleoid-associated proteins (NAPs) that are involved in vital processes such as DNA compaction and reparation, gene transcriptionetc.No data are available on the structures of HU proteins from mycoplasmas. To this end, the