Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dmitry I. Pozdnyakov"'
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 7, Pp 871-881 (2022)
Objective(s): The study aims to estimate the neuroprotective effect of chromone derivatives in the sporadic form of Alzheimer’s disease in the context of the relationship between changes in mitochondrial function and neuroinflammation.Materials and
Externí odkaz:
https://doaj.org/article/d0681b4240004040b562d764f4c8a0db
Autor:
Dmitry I. Pozdnyakov, Zhanna V. Dayronas, Denis S. Zolotych, Anastasya D. Geraschenko, Natalya B. Shabanova
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 2, Pp 59-68 (2022)
Introduction: Neuroprotection is a promising area of adjuvant therapy of ischemic brain lesions. At the same time, among potentially effective neuroprotectors, herbal remedies are distinguished due to their high efficiency and safety of use. In this
Externí odkaz:
https://doaj.org/article/815d2365a2ef435f92c40d46e2dd5189
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 1, Pp 13-22 (2022)
Introduction: The aim of the study was to investigate the dose-dependent actoprotective effect of ATACL on physical performance and psychoemotional status of animals under conditions of exhausting exercise. Materials and methods: Outbred male mice (2
Externí odkaz:
https://doaj.org/article/07d8aa81c1bb467b8ce9708449687dd6
Publikováno v:
Chimica Techno Acta, Vol 9, Iss 2 (2022)
Neurodegenerative processes of the central nervous system are an important socially significant problem of modern society. They cause many diseases, such as Alzheimer's disease and cerebral ischemia, which significantly reduce the quality of human li
Externí odkaz:
https://doaj.org/article/9ee3996eaf2c46e5888f1cac903ed32c
Publikováno v:
Chimica Techno Acta, Vol 9, Iss 2 (2022)
Alzheimer's disease is a chronic neurodegenerative disease, which is characterized mainly by a progressive decrease in intellectual abilities, memory impairment and a change in a person's personality. Unfortunately, there are practically no medicines
Externí odkaz:
https://doaj.org/article/b29f0316433240dfb1750ad76e3c82ee
Publikováno v:
Research Results in Pharmacology, Vol 6, Iss 4, Pp 29-42 (2020)
Introduction: In this study, the neuroprotective effect of L-carnitine administered per os in a dose of 25 mg/kg – 800 mg/kg was evaluated. The effects of L-carnitine on changes in mitochondrial function were also studied. Materials and Methods: Th
Externí odkaz:
https://doaj.org/article/051d0309c45f4bab9630f2194053323c
Publikováno v:
Medicina, Vol 55, Iss 7, p 386 (2019)
Background and objectives: To evaluate the effect of a new pyrimidine derivative on the change of mitochondrial function in experimental chronic traumatic encephalopathy. Materials and methods: The study was performed on male mice of the BALB/c line
Externí odkaz:
https://doaj.org/article/5909197f8f214597bc349f83f333fd0b
Autor:
Elizaveta K. Melnikova, Gleb S. Denisov, Stanislav S. Shatokhin, Alina A. Markova, Boris M. Bulychev, S.C. Gagieva, Vladislav A. Tuskaev, Eduard T. Oganesyan, Dmitry I. Pozdnyakov
Publikováno v:
New Journal of Chemistry. 46:621-631
The condensation of 3-formylchromones and 6-amino-5-((3,5-di-tert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino)-1,3-dimethyl-pyrimidine-2,4(1H,3H)-dione allowed us to synthesize chromone based hybrids containing additional pharmacophores - xanthine
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 34, Iss 1, Pp 42-48 (2021)
The aim of the study. To evaluate the effect of succinic acid derivatives on changes of mitochondrial function in rats under cerebral ischemia conditions. Materials and methods. In this work, the effect of succinic acid, ethylmethylhydroxypyridine su
Autor:
Dmitry I. Pozdnyakov, Eduard T. Oganesyan, Andrey V. Voronkov, Similla Adzhiahmetova, Nadezhda M. Chervonnaya
Publikováno v:
Journal of Medicinal Plants, Vol 20, Iss 77, Pp 60-78 (2021)
Background: Stress is an integral part of human life and leads to maladaptation of the organism and needs rational pharmacological correction. Objective: The purpose of this experiment was to evaluate the adaptogenic potential of European mistletoe e