Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Dmitry I. Osolodkin"'
Autor:
Andrey Moiseenko, Yichen Zhang, Mikhail F. Vorovitch, Alla L. Ivanova, Zheng Liu, Dmitry I. Osolodkin, Alexey M. Egorov, Aydar A. Ishmukhametov, Olga S. Sokolova
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTThe main approach to preventing tick-borne encephalitis (TBE) is vaccination. Formaldehyde-inactivated TBE vaccines have a proven record of safety and efficiency but have never been characterized structurally with atomic resolution. We report
Externí odkaz:
https://doaj.org/article/8978a4d1662043f8b42d012a151aac91
Autor:
Evgeny B. Pichkur, Mikhail F. Vorovitch, Alla L. Ivanova, Elena V. Protopopova, Valery B. Loktev, Dmitry I. Osolodkin, Aydar A. Ishmukhametov, Valeriya R. Samygina
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTTick-borne encephalitis virus (TBEV) causes a severe disease, tick-borne encephalitis (TBE), that has a substantial epidemiological importance for Northern Eurasia. Between 10,000 and 15,000 TBE cases are registered annually despite the avail
Externí odkaz:
https://doaj.org/article/c8c766a04fd34eb5b0173f8e54e4a91d
Autor:
Kseniya N. Sedenkova, Artem S. Sazonov, Dmitry A. Vasilenko, Kristian S. Andriasov, Marina G. Eremenko, Yuri K. Grishin, Evgeny V. Khvatov, Alexander S. Goryashchenko, Victoria I. Uvarova, Dmitry I. Osolodkin, Aydar A. Ishmukhametov, Elena B. Averina
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10758 (2023)
Spirocyclic compounds containing heterocyclic moieties represent promising 3D scaffolds for modern drug design. In the search for novel anti-flaviviral agents, we have obtained a series of 3-[N,N-bis(sulfonyl)amino]isoxazolines containing spiro-annul
Externí odkaz:
https://doaj.org/article/1abd5c01074f4c61b5fa0d5b30ff0041
Autor:
Ekaterina A. Sosnina, Sergey Sosnin, Anastasia A. Nikitina, Ivan Nazarov, Dmitry I. Osolodkin, Maxim V. Fedorov
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15039-15051 (2020)
Externí odkaz:
https://doaj.org/article/d4a115e29ae040b1b69899c196f75e64
Autor:
Maria Yu. Zakharova, Alexandra A. Kuznetsova, Victoria I. Uvarova, Anastasiia D. Fomina, Liubov I. Kozlovskaya, Elena N. Kaliberda, Inna N. Kurbatskaia, Ivan V. Smirnov, Anatoly A. Bulygin, Vera D. Knorre, Olga S. Fedorova, Alexandre Varnek, Dmitry I. Osolodkin, Aydar A. Ishmukhametov, Alexey M. Egorov, Alexander G. Gabibov, Nikita A. Kuznetsov
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The design of effective target-specific drugs for COVID-19 treatment has become an intriguing challenge for modern science. The SARS-CoV-2 main protease, Mpro, responsible for the processing of SARS-CoV-2 polyproteins and production of individual com
Externí odkaz:
https://doaj.org/article/d34b9bc2a37f410db93fca2863eda72a
Autor:
Andrey V. Moiseenko, Dmitry V. Bagrov, Mikhail F. Vorovitch, Victoria I. Uvarova, Maxim M. Veselov, Anastasia V. Kashchenko, Alla L. Ivanova, Dmitry I. Osolodkin, Alexey M. Egorov, Aydar A. Ishmukhametov, Konstantin V. Shaitan, Olga S. Sokolova
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2478 (2022)
Tick-borne encephalitis virus (TBEV) is an enveloped RNA virus, a member of the genus Flavivirus (family Flaviviridae). Here, we provide a detailed analysis of the size and structure of the inactivated TBEV vaccine strain Sofjin-Chumakov. Four analyt
Externí odkaz:
https://doaj.org/article/d07a16983a5d4ef09befa67f91bdd275
Autor:
Valeriya R. Samygina, Evgeny B. Pichkur, Mikhail F. Vorovich, Petr V. Konarev, Georgy S. Peters, Dmitry I. Osolodkin, Aidar A. Ishmukhametov, Alexey M. Egorov
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S29-S30 (2019)
Background: Tick-borne encephalitis virus (TBEV) from flavivirus family is an important human pathogen causing a wide range of symptoms from uncomplicated fevers to encephalitis and meningoencephalitis. XFEL studies can provide new insight into TBEV
Externí odkaz:
https://doaj.org/article/365fb0e2be2d47b9920169e778bb51ba
Autor:
Anton Y. Fedotov, Mikhail F. Vorovitch, Kseniya K. Tuchinskaya, Konstantin V. Grishin, Olga I. Konyushko, Dmitry I. Osolodkin, Aidar A. Ishmukhametov, Alexey M. Egorov
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S29-S29 (2019)
Background: Tick-borne encephalitis virus (TBEV), a member of genus Flavivirus, is an important human pathogen: up to 10,000 cases of TBE disease are registered in Europe and Asia annually. Inactivated vaccines are widely used to prevent the disease.
Externí odkaz:
https://doaj.org/article/3fb61f19736b45f08d28bb687eb9f9e7
Autor:
Liubov L. Chernokhaeva, Yulia V. Rogova, Liubov I. Kozlovskaya, Lidiya I. Romanova, Dmitry I. Osolodkin, Mikhail F. Vorovitch, Galina G. Karganova
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Tick-borne encephalitis (TBE), caused by the TBE virus (TBEV), is a serious public health threat in northern Eurasia. Three subtypes of TBEV are distinguished. Inactivated vaccines are available for TBE prophylaxis, and their efficacy to prevent the
Externí odkaz:
https://doaj.org/article/7d0d2d1b71984087bb53b5b305a631e5
Autor:
Dmitry V. Arkhipov, Sergey N. Lomin, Yulia A. Myakushina, Ekaterina M. Savelieva, Dmitry I. Osolodkin, Georgy A. Romanov
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2096 (2019)
The signaling of cytokinins (CKs), classical plant hormones, is based on the interaction of proteins that constitute the multistep phosphorelay system (MSP): catalytic receptors—sensor histidine kinases (HKs), phosphotransmitters (HPts), and transc
Externí odkaz:
https://doaj.org/article/4196251ce28f4a0391db09a2928d3ed4