Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Dmitry G. Shpakovski"'
1
Akademický článek
Molecular mechanisms of the juvenile form of Batten disease: important role of MAPK signaling pathways (ERK1/ERK2, JNK and p38) in pathogenesis of the malady
Autor: Elena K. Shematorova, Dmitry G. Shpakovski, Anna D. Chernysheva, George V. Shpakovski
Publikováno v: Biology Direct, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Background Mutations in the CLN3 gene lead to so far an incurable juvenile-onset neuronal ceroid lipofuscinosis (JNCL) or Batten disease that starts at the age of 4–6 years with a progressive retinopathy leading to blindness. Motor disturb
Externí odkaz: https://doaj.org/article/f78a10a255d44a4393fb15e8319a415d
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2
Akademický článek
A key enzyme of animal steroidogenesis can function in plants enhancing their immunity and accelerating the processes of growth and development
Autor: George V. Shpakovski, Svetlana G. Spivak, Irina N. Berdichevets, Olga G. Babak, Svetlana V. Kubrak, Alexander V. Kilchevsky, Andrey V. Aralov, Ivan Yu. Slovokhotov, Dmitry G. Shpakovski, Ekaterina N. Baranova, Marat R. Khaliluev, Elena K. Shematorova
Publikováno v: BMC Plant Biology, Vol 17, Iss S1, Pp 1-13 (2017)
Abstract Background The initial stage of the biosynthesis of steroid hormones in animals occurs in the mitochondria of steroidogenic tissues, where cytochrome P450SCC (CYP11A1) encoded by the CYP11A1 gene catalyzes the conversion of cholesterol into
Externí odkaz: https://doaj.org/article/eab927c9ce47453da599401a1a263815
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3
Akademický článek
Mitochondria as a Possible Place for Initial Stages of Steroid Biosynthesis in Plants
Autor: Elena K. Shematorova, Ivan Yu. Slovokhotov, Marat R. Khaliluev, Irina N. Berdichevets, Ekaterina N. Baranova, Olga G. Babak, Dmitry G. Shpakovski, Svetlana G. Spivak, George V. Shpakovski
Publikováno v: Journal of Stress Physiology & Biochemistry, Vol 10, Iss 4, Pp 85-97 (2014)
With the aim of thorough comparison of steroidogenic systems of plants and animals, transgenic plants of Solanaceae family expressing CYP11A1 cDNA encoding cytochrome P450SCC of mammalian mitochondria were further analysed. Positive effect of CYP11A1
Externí odkaz: https://doaj.org/article/9f96a0054f18478a8043259fb20b3520
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4
Novel Interactions of Adrenodoxin-Related [2Fe-2S] Plant Ferredoxins MFDX1 and MFDX2 Indicate Their Involvement in a Wide Spectrum of Functions in Plant Mitochondria
Autor: Elena K. Shematorova, Yuri M. Konstantinov, V. N. Shmakov, Ivan Yu. Slovokhotov, Marat R. Khaliluev, Dmitry G. Shpakovski, Svetlana G. Spivak, George V. Shpakovski, O. G. Babak, V.N. Klykov
Publikováno v: Proceedings of the Latvian Academy of Sciences. Section B, Natural Sciences, Vol 73, Iss 6, Pp 478-486 (2019)
Electron transfer chains of plant organelles (both chloroplasts and mitochondria) contain their own special set of ferredoxins. The relatively recently described adrenodoxin-like [2Fe-2S]-ferredoxins MFDX1 and MFDX2 of plant mitochondria are among th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f80c09ab58fa8bc480420ca36e8e1dd
https://doaj.org/article/349425c2a2304f318e9e00efee713ed5
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5
Specific cytochromes P450 and adrenodoxin-like mitochondrial ferredoxins as components of the progesterone hormone system of higher plants involved in comprehensive protection from biotic and abiotic stresse
Autor: T. A. Tereshonkova, George V. Shpakovski, O. G. Babak, V.N. Klykov, A. V. Kilchevsky, Marat R. Khaliluev, Elena K. Shematorova, S. G. Spivak, Yu. V. Doludin, E. N. Baranova, I.Yu. Slovokhotov, Dmitry G. Shpakovski
Publikováno v: Abstract book of the 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology" PLAMIC2020.
In plants, along with the brassinosteroid, the older progesterone hormone system also functions. We have characterized some components of this system and shown its importance for enhancing plant immunity.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fafcf0b594fa731f10cc44269837bb9a
https://doi.org/10.28983/plamic2020.225
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6
Targeted Protection of Mitochondria of Mesophyll Cells in Transgenic CYP11A1 CDNA Expressing Tobacco Plant Leaves After NaCl-Induced Stress Damage
Autor: George V. Shpakovski, O. G. Babak, Dmitry G. Shpakovski, V.N. Klykov, Lilia R. Bogoutdinova, Svetlana G. Spivak, Elena K. Shematorova, A. V. Kilchevsky, Marat R. Khaliluev, E. N. Baranova
Publikováno v: Proceedings of the Latvian Academy of Sciences. Section B, Natural Sciences, Vol 72, Iss 6, Pp 334-340 (2018)
Recently we have showed that the expression of the mammalian CYP11A1 cDNA in plants confers their resistance to abiotic and biotic stresses. To determine the role of heterologous expression of cytochrome P450scc cDNA in resistance to ROS (radical oxy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c25204cf0e2a077cb03a26f4561430
https://doi.org/10.2478/prolas-2018-0048
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7
Molecular mechanisms of the juvenile form of Batten disease: important role of MAPK signaling pathways (ERK1/ERK2, JNK and p38) in pathogenesis of the malady
Autor: George V. Shpakovski, Elena K. Shematorova, Anna D. Chernysheva, Dmitry G. Shpakovski
Publikováno v: Biology Direct
Biology Direct, Vol 13, Iss 1, Pp 1-9 (2018)
Background Mutations in the CLN3 gene lead to so far an incurable juvenile-onset neuronal ceroid lipofuscinosis (JNCL) or Batten disease that starts at the age of 4–6 years with a progressive retinopathy leading to blindness. Motor disturbances, ep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83be869b3f271ac22af32dd2c85c5948
https://doi.org/10.1186/s13062-018-0212-y
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9
A key enzyme of animal steroidogenesis can function in plants enhancing their immunity and accelerating the processes of growth and development
Autor: Elena K. Shematorova, Andrey V. Aralov, Irina N. Berdichevets, Marat R. Khaliluev, Ivan Yu. Slovokhotov, Svetlana V. Kubrak, Svetlana G. Spivak, A. V. Kilchevsky, Dmitry G. Shpakovski, E. N. Baranova, George V. Shpakovski, O. G. Babak
Publikováno v: BMC Plant Biology
BMC Plant Biology, Vol 17, Iss S1, Pp 1-13 (2017)
Background The initial stage of the biosynthesis of steroid hormones in animals occurs in the mitochondria of steroidogenic tissues, where cytochrome P450SCC (CYP11A1) encoded by the CYP11A1 gene catalyzes the conversion of cholesterol into pregnenol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1e13e105a76af1f5bf17abb3878ec2
http://europepmc.org/articles/PMC5688476
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10
Novel complexes of gene expression and their role in the appearance and evolution of the genus Homo
Autor: Elena K. Shematorova, George V. Shpakovski, Dmitry G. Shpakovski
Publikováno v: Cell and Tissue Biology. 7:314-319
Using genetic (yeast two-hybrid system) and biochemical (coprecipitation of proteins from cellular lysates) approaches, we have performed a whole-genome wide search for interacting partners of variants of the hRPB11 subunit of human RNA polymerase II
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e783ecfab50fff664b00c8e3240a6625
https://doi.org/10.1134/s1990519x13040135
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